Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal

Detalhes bibliográficos
Autor(a) principal: Pastorinho, M. Ramiro
Data de Publicação: 2018
Outros Autores: Gonçalves, D., Barros, R., Silva, T., Henriques, I., Amaro, R., Teixeira, J.P., Miranda, S., Marques, A., Valente, C., Taborda-Barata, L., Ishizuka, M., Sousa, Ana Catarina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/27600
https://doi.org/10.14869/TOXPT.45.1.0_p-105
Resumo: Estarreja is a highly industrialized municipality in NW Portugal, well known for its historical mercury contamination. Some reports have linked hypertension and mercury exposure. In this work, we collected house dust samples and hair from the residents of this area, together with systolic (SBP) and diastolic (DBP) blood pressure. Hair mercury levels varied between 624 and 4535 ng/g, and mercury in dust varied from 93 to 9100 ng/g. No statistically significant association between dust and hair could be established (Spearman Rank Order Correlation, p=0.199). SBP varied between 175 and 116 whereas DBP ranged from 70 to 121 mm Hg, meaning that 28% of the participants were hypertensive. However, no statistically significant differences in mercury concentration between the hypertensive and normal group were found (One-tailed P-value = 0.444). Furthermore, no significant associations between SBP (p=0.826) or DBP (p=0.695) and hair mercury levels were obtained. However, 44% of individuals exhibited hair mercury levels higher than the acceptable dose set by the WHO (2000 ng/g), 72% exhibited levels higher than the acceptable dose set by the USEPA (1000 ng/g), and all participants exhibited mercury concentrations above the safe limit for Europe (580 ng/g).
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spelling Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern PortugalEstarreja is a highly industrialized municipality in NW Portugal, well known for its historical mercury contamination. Some reports have linked hypertension and mercury exposure. In this work, we collected house dust samples and hair from the residents of this area, together with systolic (SBP) and diastolic (DBP) blood pressure. Hair mercury levels varied between 624 and 4535 ng/g, and mercury in dust varied from 93 to 9100 ng/g. No statistically significant association between dust and hair could be established (Spearman Rank Order Correlation, p=0.199). SBP varied between 175 and 116 whereas DBP ranged from 70 to 121 mm Hg, meaning that 28% of the participants were hypertensive. However, no statistically significant differences in mercury concentration between the hypertensive and normal group were found (One-tailed P-value = 0.444). Furthermore, no significant associations between SBP (p=0.826) or DBP (p=0.695) and hair mercury levels were obtained. However, 44% of individuals exhibited hair mercury levels higher than the acceptable dose set by the WHO (2000 ng/g), 72% exhibited levels higher than the acceptable dose set by the USEPA (1000 ng/g), and all participants exhibited mercury concentrations above the safe limit for Europe (580 ng/g).The Journal of Toxicological Sciences2020-03-02T15:21:23Z2020-03-022018-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/27600http://hdl.handle.net/10174/27600https://doi.org/10.14869/TOXPT.45.1.0_p-105engPastorinho MR, Gonçalves D, Barros R, Silva T, Henriques I, Amaro R, Teixeira JP, Miranda S, Marques A, Valente C, Taborda-Barata L, Ishizuka M, Sousa ACA (2018) Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal. The Journal of Toxicological Sciences, 43, S261https://www.jstage.jst.go.jp/article/toxpt/45.1/0/45.1_P-105/_article/-char/enrpastorinho@uevora.ptndndndndndndndndndndndanasousa@ua.pt239Pastorinho, M. RamiroGonçalves, D.Barros, R.Silva, T.Henriques, I.Amaro, R.Teixeira, J.P.Miranda, S.Marques, A.Valente, C.Taborda-Barata, L.Ishizuka, M.Sousa, Ana Catarinainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:23:07Zoai:dspace.uevora.pt:10174/27600Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:17:36.731233Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
title Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
spellingShingle Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
Pastorinho, M. Ramiro
title_short Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
title_full Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
title_fullStr Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
title_full_unstemmed Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
title_sort Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal
author Pastorinho, M. Ramiro
author_facet Pastorinho, M. Ramiro
Gonçalves, D.
Barros, R.
Silva, T.
Henriques, I.
Amaro, R.
Teixeira, J.P.
Miranda, S.
Marques, A.
Valente, C.
Taborda-Barata, L.
Ishizuka, M.
Sousa, Ana Catarina
author_role author
author2 Gonçalves, D.
Barros, R.
Silva, T.
Henriques, I.
Amaro, R.
Teixeira, J.P.
Miranda, S.
Marques, A.
Valente, C.
Taborda-Barata, L.
Ishizuka, M.
Sousa, Ana Catarina
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pastorinho, M. Ramiro
Gonçalves, D.
Barros, R.
Silva, T.
Henriques, I.
Amaro, R.
Teixeira, J.P.
Miranda, S.
Marques, A.
Valente, C.
Taborda-Barata, L.
Ishizuka, M.
Sousa, Ana Catarina
description Estarreja is a highly industrialized municipality in NW Portugal, well known for its historical mercury contamination. Some reports have linked hypertension and mercury exposure. In this work, we collected house dust samples and hair from the residents of this area, together with systolic (SBP) and diastolic (DBP) blood pressure. Hair mercury levels varied between 624 and 4535 ng/g, and mercury in dust varied from 93 to 9100 ng/g. No statistically significant association between dust and hair could be established (Spearman Rank Order Correlation, p=0.199). SBP varied between 175 and 116 whereas DBP ranged from 70 to 121 mm Hg, meaning that 28% of the participants were hypertensive. However, no statistically significant differences in mercury concentration between the hypertensive and normal group were found (One-tailed P-value = 0.444). Furthermore, no significant associations between SBP (p=0.826) or DBP (p=0.695) and hair mercury levels were obtained. However, 44% of individuals exhibited hair mercury levels higher than the acceptable dose set by the WHO (2000 ng/g), 72% exhibited levels higher than the acceptable dose set by the USEPA (1000 ng/g), and all participants exhibited mercury concentrations above the safe limit for Europe (580 ng/g).
publishDate 2018
dc.date.none.fl_str_mv 2018-09-01T00:00:00Z
2020-03-02T15:21:23Z
2020-03-02
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/27600
http://hdl.handle.net/10174/27600
https://doi.org/10.14869/TOXPT.45.1.0_p-105
url http://hdl.handle.net/10174/27600
https://doi.org/10.14869/TOXPT.45.1.0_p-105
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pastorinho MR, Gonçalves D, Barros R, Silva T, Henriques I, Amaro R, Teixeira JP, Miranda S, Marques A, Valente C, Taborda-Barata L, Ishizuka M, Sousa ACA (2018) Mercury and Blood Pressure Levels in Inhabitants from a Highly Industrialized Region in Northern Portugal. The Journal of Toxicological Sciences, 43, S261
https://www.jstage.jst.go.jp/article/toxpt/45.1/0/45.1_P-105/_article/-char/en
rpastorinho@uevora.pt
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nd
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anasousa@ua.pt
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv The Journal of Toxicological Sciences
publisher.none.fl_str_mv The Journal of Toxicological Sciences
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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