Neonatal Mastitis: 12 Years of Experience

Detalhes bibliográficos
Autor(a) principal: Brett, Ana
Data de Publicação: 2012
Outros Autores: Gonçalves, Sara, Luz, Alexandra, Martins, Dora, Oliveira, Henrique, Januário, Luís, Rodrigues, Fernanda
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/64
Resumo: Introduction and Aims: Mastitis is an inflammation of the breast that may be accompanied by an infectious process. The most frequently isolated bacteria is Staphylococcus aureus. The vast majority of cases are unilateral and have good prognosis. The aim of this study was to characterize neonatal infectious mastitis diagnosed and treated in a tertiary hospital. Methods: Retrospective analysis of all clinical records of infants < 2 months of age diagnosed with neonatal mastitis between January 2000 and June 2011. Clinical, laboratory and microbiological data, as well as treatment and outcome, were analyzed. Results: Twenty-one children met inclusion criteria, fourteen were female. The median age at diagnosis was 21 days. Mastitis was unilateral in 19 cases. The most frequent signs were swelling and erythema. Fever was documented in three children. The bacteria identified in the breast exudate was methicillin susceptible Staphylococcus aureus in six cases and methicillin-resistant Staphylococcus aureus in three cases. The most frequently used antibiotic was flucloxacillin, with a median duration of ten days. There were 11 cases of breast abscess, ten drained surgically and one with spontaneous drainage. In two cases with isolation of methicillin-resistant Staphylococcus aureus there was a good outcome with surgical drainage, despite treatment with a β-lactam. There were no other complications. Conclusions: As described in literature, in this series neonatal mastitis was more frequent in girls and unilateral. The development of breast abscess occurred in half of the cases. The only bacteria isolated was Staphylococcus aureus (9 cases), methicillin resistant in three cases, two of which with good outcome with surgical drainage, despite treatment with a β-lactam.
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spelling Neonatal Mastitis: 12 Years of ExperienceMastite neonatal: experiência de 12 anosIntroduction and Aims: Mastitis is an inflammation of the breast that may be accompanied by an infectious process. The most frequently isolated bacteria is Staphylococcus aureus. The vast majority of cases are unilateral and have good prognosis. The aim of this study was to characterize neonatal infectious mastitis diagnosed and treated in a tertiary hospital. Methods: Retrospective analysis of all clinical records of infants < 2 months of age diagnosed with neonatal mastitis between January 2000 and June 2011. Clinical, laboratory and microbiological data, as well as treatment and outcome, were analyzed. Results: Twenty-one children met inclusion criteria, fourteen were female. The median age at diagnosis was 21 days. Mastitis was unilateral in 19 cases. The most frequent signs were swelling and erythema. Fever was documented in three children. The bacteria identified in the breast exudate was methicillin susceptible Staphylococcus aureus in six cases and methicillin-resistant Staphylococcus aureus in three cases. The most frequently used antibiotic was flucloxacillin, with a median duration of ten days. There were 11 cases of breast abscess, ten drained surgically and one with spontaneous drainage. In two cases with isolation of methicillin-resistant Staphylococcus aureus there was a good outcome with surgical drainage, despite treatment with a β-lactam. There were no other complications. Conclusions: As described in literature, in this series neonatal mastitis was more frequent in girls and unilateral. The development of breast abscess occurred in half of the cases. The only bacteria isolated was Staphylococcus aureus (9 cases), methicillin resistant in three cases, two of which with good outcome with surgical drainage, despite treatment with a β-lactam.Introdução e Objectivos: A mastite é uma inflamação da mama, que pode ou não ser acompanhada de processo infeccioso, sendo o Staphylococcus aureus o gérmen mais frequentemente isolado. A grande maioria dos casos é unilateral e tem bom prognóstico. O objectivo deste estudo foi caracterizar as mastites neonatais infecciosas diagnosticadas e tratadas num hospital de nível 3. Métodos: Análise retrospectiva dos processos clínicos de lactentes com menos de dois meses com diagnóstico de mastite neonatal, observados entre Janeiro de 2000 e Dezembro de 2011. Foram avaliados aspectos clínicos, laboratoriais e microbiológicos bem como o tratamento instituído e evolução. Resultados: Foram incluídos 21 lactentes, 14 do sexo feminino. A mediana da idade de diagnóstico foi de 21 dias. A mastite foi unilateral em 19 casos. Os sinais clínicos mais frequentes foram tumefacção e eritema. Em três crianças foi documentada febre. O agente isolado no exsudato mamário foi Staphylococcus aureus, meticilina susceptível em seis casos e meticilina resistente em três. A terapêutica antibiótica mais utilizada foi a flucloxacilina, com duração mediana de dez dias. Registaram-se 11 casos de abcesso mamário, dez drenados cirurgicamente e um com drenagem espontânea. Em dois casos com identificação de Staphylococcus aureus meticilina resistente houve evolução favorável com drenagem cirúrgica, apesar de antibioticoterapia com β-lactâmico. Não ocorreu outro tipo de complicações. Conclusões: Tal como descrito na literatura, nesta série a mastite neonatal foi mais frequente no sexo feminino e unilateral. Em metade dos casos ocorreu formação de abcesso mamário. O único gérmen isolado foi Staphylococcus aureus (nove casos), sendo meticilina resistente em três, dois destes com evolução favorável com drenagem cirúrgica apesar de antibioticoterapia com β-lactâmico.Ordem dos Médicos2012-08-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/64oai:ojs.www.actamedicaportuguesa.com:article/64Acta Médica Portuguesa; Vol. 25 No. 4 (2012): July-August; 207-212Acta Médica Portuguesa; Vol. 25 N.º 4 (2012): Julho-Agosto; 207-2121646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/64https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/64/50Brett, AnaGonçalves, SaraLuz, AlexandraMartins, DoraOliveira, HenriqueJanuário, LuísRodrigues, Fernandainfo:eu-repo/semantics/openAccess2022-12-20T10:55:46Zoai:ojs.www.actamedicaportuguesa.com:article/64Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:21.870558Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Neonatal Mastitis: 12 Years of Experience
Mastite neonatal: experiência de 12 anos
title Neonatal Mastitis: 12 Years of Experience
spellingShingle Neonatal Mastitis: 12 Years of Experience
Brett, Ana
title_short Neonatal Mastitis: 12 Years of Experience
title_full Neonatal Mastitis: 12 Years of Experience
title_fullStr Neonatal Mastitis: 12 Years of Experience
title_full_unstemmed Neonatal Mastitis: 12 Years of Experience
title_sort Neonatal Mastitis: 12 Years of Experience
author Brett, Ana
author_facet Brett, Ana
Gonçalves, Sara
Luz, Alexandra
Martins, Dora
Oliveira, Henrique
Januário, Luís
Rodrigues, Fernanda
author_role author
author2 Gonçalves, Sara
Luz, Alexandra
Martins, Dora
Oliveira, Henrique
Januário, Luís
Rodrigues, Fernanda
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Brett, Ana
Gonçalves, Sara
Luz, Alexandra
Martins, Dora
Oliveira, Henrique
Januário, Luís
Rodrigues, Fernanda
description Introduction and Aims: Mastitis is an inflammation of the breast that may be accompanied by an infectious process. The most frequently isolated bacteria is Staphylococcus aureus. The vast majority of cases are unilateral and have good prognosis. The aim of this study was to characterize neonatal infectious mastitis diagnosed and treated in a tertiary hospital. Methods: Retrospective analysis of all clinical records of infants < 2 months of age diagnosed with neonatal mastitis between January 2000 and June 2011. Clinical, laboratory and microbiological data, as well as treatment and outcome, were analyzed. Results: Twenty-one children met inclusion criteria, fourteen were female. The median age at diagnosis was 21 days. Mastitis was unilateral in 19 cases. The most frequent signs were swelling and erythema. Fever was documented in three children. The bacteria identified in the breast exudate was methicillin susceptible Staphylococcus aureus in six cases and methicillin-resistant Staphylococcus aureus in three cases. The most frequently used antibiotic was flucloxacillin, with a median duration of ten days. There were 11 cases of breast abscess, ten drained surgically and one with spontaneous drainage. In two cases with isolation of methicillin-resistant Staphylococcus aureus there was a good outcome with surgical drainage, despite treatment with a β-lactam. There were no other complications. Conclusions: As described in literature, in this series neonatal mastitis was more frequent in girls and unilateral. The development of breast abscess occurred in half of the cases. The only bacteria isolated was Staphylococcus aureus (9 cases), methicillin resistant in three cases, two of which with good outcome with surgical drainage, despite treatment with a β-lactam.
publishDate 2012
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publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 25 No. 4 (2012): July-August; 207-212
Acta Médica Portuguesa; Vol. 25 N.º 4 (2012): Julho-Agosto; 207-212
1646-0758
0870-399X
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