A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe
| Autor(a) principal: | |
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| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/56556 |
Resumo: | © 2019 European Association for the Study of the Liver. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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A cross-sectional study of the public health response to non-alcoholic fatty liver disease in EuropeEuropeGuidelines as topicHealth PolicyNon-alcoholic fatty liver disease (NAFLD)Non-alcoholic steatohepatitis (NASH)Review© 2019 European Association for the Study of the Liver. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Background & aims: Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem worldwide and has become an important field of biomedical inquiry. We aimed to determine whether European countries have mounted an adequate public health response to NAFLD and non-alcoholic steatohepatitis (NASH). Methods: In 2018 and 2019, NAFLD experts in 29 European countries completed an English-language survey on policies, guidelines, awareness, monitoring, diagnosis and clinical assessment in their country. The data were compiled, quality checked against existing official documents and reported descriptively. Results: None of the 29 participating countries had written strategies or action plans for NAFLD. Two countries (7%) had mentions of NAFLD or NASH in related existing strategies (obesity and alcohol). Ten (34%) reported having national clinical guidelines specifically addressing NAFLD and, upon diagnosis, all included recommendations for the assessment of diabetes and liver cirrhosis. Eleven countries (38%) recommended screening for NAFLD in all patients with either diabetes, obesity and/or metabolic syndrome. Five countries (17%) had referral algorithms for follow-up and specialist referral in primary care, and 7 (24%) reported structured lifestyle programmes aimed at NAFLD. Seven (24%) had funded awareness campaigns that specifically included prevention of liver disease. Four countries (14%) reported having civil society groups which address NAFLD and 3 countries (10%) had national registries that include NAFLD. Conclusions: We found that a comprehensive public health response to NAFLD is lacking in the surveyed European countries. This includes policy in the form of a strategy, clinical guidelines, awareness campaigns, civil society involvement, and health systems organisation, including registries. Lay summary: We conducted a survey on non-alcoholic fatty liver disease with experts in European countries, coupled with data extracted from official documents on policies, clinical guidelines, awareness, and monitoring. We found a general lack of national policies, awareness campaigns and civil society involvement, and few epidemiological registries.Financial support for this research was provided by the EASL International Liver Foundation through grants from Gilead Sciences Europe Ltd., Allergan Pharmaceutical International Ltd., Bristol-Myers-Squibb Company, Pfizer Inc., and Resoundant Inc. JVL is a Miguel Servet-funded researcher at ISGlobal, Hospital Clínic, University of Barcelona. QMA and VR are members of the EPoS (Elucidating Pathways of Steatohepatitis) consortium funded by the Horizon 2020 Framework Program of the European Union under Grant Agreement 634413. QMA, VR, HCP, ME, MRG, HCP are members of the LITMUS (Liver Investigation: Testing Marker Utility in Steatohepatitis) consortium funded by the IMI2 Program of the European Union under Grant Agreement 777377. QMA is a Newcastle NIHR Biomedical Research Centre investigator.ElsevierRepositório da Universidade de LisboaLazarus, Jeffrey V.Ekstedt, MattiasMarchesini, GiulioMullen, JillianNovak, KatjaPericàs, Juan M.Roel, ElenaRomero-Gómez, ManuelRatziu, VladTacke, FrankCortez-Pinto, HelenaAnstee, Quentin M.2023-03-07T11:40:36Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/56556engJ Hepatol. 2020 Jan;72(1):14-240168-827810.1016/j.jhep.2019.08.0271600-0641info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:04:12Zoai:repositorio.ul.pt:10451/56556Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:07:05.171702Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| title |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| spellingShingle |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe Lazarus, Jeffrey V. Europe Guidelines as topic Health Policy Non-alcoholic fatty liver disease (NAFLD) Non-alcoholic steatohepatitis (NASH) Review |
| title_short |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| title_full |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| title_fullStr |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| title_full_unstemmed |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| title_sort |
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe |
| author |
Lazarus, Jeffrey V. |
| author_facet |
Lazarus, Jeffrey V. Ekstedt, Mattias Marchesini, Giulio Mullen, Jillian Novak, Katja Pericàs, Juan M. Roel, Elena Romero-Gómez, Manuel Ratziu, Vlad Tacke, Frank Cortez-Pinto, Helena Anstee, Quentin M. |
| author_role |
author |
| author2 |
Ekstedt, Mattias Marchesini, Giulio Mullen, Jillian Novak, Katja Pericàs, Juan M. Roel, Elena Romero-Gómez, Manuel Ratziu, Vlad Tacke, Frank Cortez-Pinto, Helena Anstee, Quentin M. |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Lazarus, Jeffrey V. Ekstedt, Mattias Marchesini, Giulio Mullen, Jillian Novak, Katja Pericàs, Juan M. Roel, Elena Romero-Gómez, Manuel Ratziu, Vlad Tacke, Frank Cortez-Pinto, Helena Anstee, Quentin M. |
| dc.subject.por.fl_str_mv |
Europe Guidelines as topic Health Policy Non-alcoholic fatty liver disease (NAFLD) Non-alcoholic steatohepatitis (NASH) Review |
| topic |
Europe Guidelines as topic Health Policy Non-alcoholic fatty liver disease (NAFLD) Non-alcoholic steatohepatitis (NASH) Review |
| description |
© 2019 European Association for the Study of the Liver. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2023-03-07T11:40:36Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/56556 |
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http://hdl.handle.net/10451/56556 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
J Hepatol. 2020 Jan;72(1):14-24 0168-8278 10.1016/j.jhep.2019.08.027 1600-0641 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Elsevier |
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Elsevier |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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