School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study

Detalhes bibliográficos
Autor(a) principal: Paciencia, I
Data de Publicação: 2019
Outros Autores: Rufo, JC, Silva, D, Martins, C, Mendes, F, Rama, T, Rodolfo, A, Madureira, J, Delgado, L, Fernandes, ED, Padrão, Patrícia, Moreira, Pedro, Severo, M, Pina, MF, Teixeira, JP, Barros, H, Ruokolainen, L, Haahtela, T, Moreira, André
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/124954
Resumo: Children are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of the environment and the walkability surrounding schools on lung function, airway inflammation and autonomic nervous system activity. Data on 701 children from 20 primary schools were analysed. Lung function, airway inflammation and pH from exhaled breath condensate were measured. Pupillometry was performed to evaluate autonomic activity. Land use composition and walkability index were quantified within a 500 m buffer zone around schools. The proportion of effects explained by the school environment was measured by mixed-effect models. We found that green school areas tended to be associated with higher lung volumes (FVC, FEV1 and FEF25-75%) compared with built areas. FVC was significantly lower in-built than in green areas. After adjustment, the school environment explained 23%, 34% and 99.9% of the school effect on FVC, FEV1, and FEF25-75%, respectively. The walkability of school neighbourhoods was negatively associated with both pupil constriction amplitude and redilatation time, explaining -16% to 18% of parasympathetic and 8% to 29% of sympathetic activity. Our findings suggest that the environment surrounding schools has an effect on the lung function of its students. This effect may be partially mediated by the autonomic nervous system.
id RCAP_9a886d5ba78e10e891a1ae786738c2f3
oai_identifier_str oai:repositorio-aberto.up.pt:10216/124954
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional studyCiências da Saúde, Ciências médicas e da saúdeHealth sciences, Medical and Health sciencesChildren are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of the environment and the walkability surrounding schools on lung function, airway inflammation and autonomic nervous system activity. Data on 701 children from 20 primary schools were analysed. Lung function, airway inflammation and pH from exhaled breath condensate were measured. Pupillometry was performed to evaluate autonomic activity. Land use composition and walkability index were quantified within a 500 m buffer zone around schools. The proportion of effects explained by the school environment was measured by mixed-effect models. We found that green school areas tended to be associated with higher lung volumes (FVC, FEV1 and FEF25-75%) compared with built areas. FVC was significantly lower in-built than in green areas. After adjustment, the school environment explained 23%, 34% and 99.9% of the school effect on FVC, FEV1, and FEF25-75%, respectively. The walkability of school neighbourhoods was negatively associated with both pupil constriction amplitude and redilatation time, explaining -16% to 18% of parasympathetic and 8% to 29% of sympathetic activity. Our findings suggest that the environment surrounding schools has an effect on the lung function of its students. This effect may be partially mediated by the autonomic nervous system.20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/124954eng2045-232210.1038/s41598-019-51659-yPaciencia, IRufo, JCSilva, DMartins, CMendes, FRama, TRodolfo, AMadureira, JDelgado, LFernandes, EDPadrão, PatríciaMoreira, PedroSevero, MPina, MFTeixeira, JPBarros, HRuokolainen, LHaahtela, TMoreira, Andréinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:58:48Zoai:repositorio-aberto.up.pt:10216/124954Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:12:53.840324Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
title School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
spellingShingle School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
Paciencia, I
Ciências da Saúde, Ciências médicas e da saúde
Health sciences, Medical and Health sciences
title_short School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
title_full School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
title_fullStr School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
title_full_unstemmed School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
title_sort School environment associates with lung function and autonomic nervous system activity in children: a cross-sectional study
author Paciencia, I
author_facet Paciencia, I
Rufo, JC
Silva, D
Martins, C
Mendes, F
Rama, T
Rodolfo, A
Madureira, J
Delgado, L
Fernandes, ED
Padrão, Patrícia
Moreira, Pedro
Severo, M
Pina, MF
Teixeira, JP
Barros, H
Ruokolainen, L
Haahtela, T
Moreira, André
author_role author
author2 Rufo, JC
Silva, D
Martins, C
Mendes, F
Rama, T
Rodolfo, A
Madureira, J
Delgado, L
Fernandes, ED
Padrão, Patrícia
Moreira, Pedro
Severo, M
Pina, MF
Teixeira, JP
Barros, H
Ruokolainen, L
Haahtela, T
Moreira, André
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paciencia, I
Rufo, JC
Silva, D
Martins, C
Mendes, F
Rama, T
Rodolfo, A
Madureira, J
Delgado, L
Fernandes, ED
Padrão, Patrícia
Moreira, Pedro
Severo, M
Pina, MF
Teixeira, JP
Barros, H
Ruokolainen, L
Haahtela, T
Moreira, André
dc.subject.por.fl_str_mv Ciências da Saúde, Ciências médicas e da saúde
Health sciences, Medical and Health sciences
topic Ciências da Saúde, Ciências médicas e da saúde
Health sciences, Medical and Health sciences
description Children are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of the environment and the walkability surrounding schools on lung function, airway inflammation and autonomic nervous system activity. Data on 701 children from 20 primary schools were analysed. Lung function, airway inflammation and pH from exhaled breath condensate were measured. Pupillometry was performed to evaluate autonomic activity. Land use composition and walkability index were quantified within a 500 m buffer zone around schools. The proportion of effects explained by the school environment was measured by mixed-effect models. We found that green school areas tended to be associated with higher lung volumes (FVC, FEV1 and FEF25-75%) compared with built areas. FVC was significantly lower in-built than in green areas. After adjustment, the school environment explained 23%, 34% and 99.9% of the school effect on FVC, FEV1, and FEF25-75%, respectively. The walkability of school neighbourhoods was negatively associated with both pupil constriction amplitude and redilatation time, explaining -16% to 18% of parasympathetic and 8% to 29% of sympathetic activity. Our findings suggest that the environment surrounding schools has an effect on the lung function of its students. This effect may be partially mediated by the autonomic nervous system.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/124954
url https://hdl.handle.net/10216/124954
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2045-2322
10.1038/s41598-019-51659-y
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136051655081984