Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient

Detalhes bibliográficos
Autor(a) principal: Couto,Maria Eduarda
Data de Publicação: 2021
Outros Autores: Oliva,Tereza, Alberto,Pedro, Lebre,Ana, Pinto,Armando, Ferreira,Ana Maia
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542021000400241
Resumo: Abstract Aim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.
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spelling Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patientantifungalencephalitismucormycosisosteomyelitisRhizopus spAbstract Aim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.Centro Hospitalar do Porto2021-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542021000400241Nascer e Crescer v.30 n.4 2021reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-07542021000400241Couto,Maria EduardaOliva,TerezaAlberto,PedroLebre,AnaPinto,ArmandoFerreira,Ana Maiainfo:eu-repo/semantics/openAccess2024-02-06T17:06:31Zoai:scielo:S0872-07542021000400241Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:19:50.873071Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
title Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
spellingShingle Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
Couto,Maria Eduarda
antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
title_short Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
title_full Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
title_fullStr Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
title_full_unstemmed Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
title_sort Rhino-Orbital-Cerebral Mucormycosis in a pediatric cancer patient
author Couto,Maria Eduarda
author_facet Couto,Maria Eduarda
Oliva,Tereza
Alberto,Pedro
Lebre,Ana
Pinto,Armando
Ferreira,Ana Maia
author_role author
author2 Oliva,Tereza
Alberto,Pedro
Lebre,Ana
Pinto,Armando
Ferreira,Ana Maia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Couto,Maria Eduarda
Oliva,Tereza
Alberto,Pedro
Lebre,Ana
Pinto,Armando
Ferreira,Ana Maia
dc.subject.por.fl_str_mv antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
topic antifungal
encephalitis
mucormycosis
osteomyelitis
Rhizopus sp
description Abstract Aim: Mucormycosis infections are highly lethal in immunosuppressed patients. The authors present a rare case of successful treatment of the condition. Case description: A 14-year-old male with acute lymphoblastic lymphoma in remission was diagnosed with pansinusitis, cerebral osteomyelitis, and encephalitis with an abscess caused by Rhizopus sp. Neurosurgical drainage, endoscopic sinus surgery, and left eye enucleation were performed, and the patient was simultaneously treated with lipossomal-amphotericin B and posaconazol (later replaced by isavuconazol). However, complications (left frontal lobe herniation and cerebrospinal fluid fistula) ensued, requiring surgical reoperation. Chemotherapy was restarted four months later. Comments: This is a rare case report, in which early and aggressive surgery, antifungal treatment, and multidisciplinary team work were crucial for the successful outcome.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-01
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dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Centro Hospitalar do Porto
publisher.none.fl_str_mv Centro Hospitalar do Porto
dc.source.none.fl_str_mv Nascer e Crescer v.30 n.4 2021
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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