Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases

Detalhes bibliográficos
Autor(a) principal: Gabriel, André F.
Data de Publicação: 2020
Outros Autores: Costa, Marina C., Enguita, Francisco J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/54354
Resumo: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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spelling Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseasesRNA regulatory networksCardiovascular diseasescircRNAsmiRNAsnon-coding RNA© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Non-coding regulatory RNAs are generated as a core output of the eukaryotic genomes, being essential players in cell biology. At the organism level, they are key functional actors in those tissues and organs with limited proliferation capabilities such as the heart. The role of regulatory networks mediated by non-coding RNAs in the pathophysiology of cardiovascular conditions is starting to be unveiled. However, a deeper knowledge of the functional interactions among the diverse non-coding RNA families and their phenotypic consequences is required. This review presents the current knowledge about the functional crosstalk between circRNAs and other biomolecules in the framework of the cardiovascular diseases.This work is supported by COST (European Cooperation in Science and Technology) Action EU-CardioRNA CA17129 and Portuguese Foundation for Science and Technology (FCT) under the framework of the research grant PTDC-MED-GEN-29389-2017.MDPIRepositório da Universidade de LisboaGabriel, André F.Costa, Marina C.Enguita, Francisco J.2022-09-07T13:54:20Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/54354engInt J Mol Sci. 2020 Jan 10;21(2):4561661-659610.3390/ijms210204561422-0067info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:00:05Zoai:repositorio.ul.pt:10451/54354Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:04:50.821807Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
title Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
spellingShingle Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
Gabriel, André F.
RNA regulatory networks
Cardiovascular diseases
circRNAs
miRNAs
non-coding RNA
title_short Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
title_full Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
title_fullStr Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
title_full_unstemmed Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
title_sort Circular RNA-centered regulatory networks in the physiopathology of cardiovascular diseases
author Gabriel, André F.
author_facet Gabriel, André F.
Costa, Marina C.
Enguita, Francisco J.
author_role author
author2 Costa, Marina C.
Enguita, Francisco J.
author2_role author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Gabriel, André F.
Costa, Marina C.
Enguita, Francisco J.
dc.subject.por.fl_str_mv RNA regulatory networks
Cardiovascular diseases
circRNAs
miRNAs
non-coding RNA
topic RNA regulatory networks
Cardiovascular diseases
circRNAs
miRNAs
non-coding RNA
description © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2022-09-07T13:54:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/54354
url http://hdl.handle.net/10451/54354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Mol Sci. 2020 Jan 10;21(2):456
1661-6596
10.3390/ijms21020456
1422-0067
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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