Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/12937 |
Resumo: | Polymer meshes have recently attracted great attention due to their great variety of aplications in fields such as tissue engineering and drug delivery. Poly( -caprolactone) nanofibers were prepared by electrospinning giving rise to porous meshes. However, for some applications in tissue engineering where, for instance, cell migration into the inner regions of the mesh is aimed, the pore size obtained by conventional techniques is too narrow. To improve the pore size, laser irradiation with femtosecond pulses (i.e., negligible heat diffusion into the polymer material and confined excitation energy) is performed. A detailed study of the influence of the pulse energy, pulse length, and number of pulses on the topography of electrospun fiber meshes has been carried out, and the irradiated areas have been studied by scanning electron microscopy, contact angle measurements and spectroscopic techniques. The results show that using the optimal laser parameters, micropores are formed and the nature of the fibers is preserved. |
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Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiationPore sizeFemtosecond laserFiber meshElectrospinningLaser ablationScience & TechnologyPolymer meshes have recently attracted great attention due to their great variety of aplications in fields such as tissue engineering and drug delivery. Poly( -caprolactone) nanofibers were prepared by electrospinning giving rise to porous meshes. However, for some applications in tissue engineering where, for instance, cell migration into the inner regions of the mesh is aimed, the pore size obtained by conventional techniques is too narrow. To improve the pore size, laser irradiation with femtosecond pulses (i.e., negligible heat diffusion into the polymer material and confined excitation energy) is performed. A detailed study of the influence of the pulse energy, pulse length, and number of pulses on the topography of electrospun fiber meshes has been carried out, and the irradiated areas have been studied by scanning electron microscopy, contact angle measurements and spectroscopic techniques. The results show that using the optimal laser parameters, micropores are formed and the nature of the fibers is preserved.European Integrated Project GENOSTEM (LSH-STREP-CT-2003-503161); European Network of Excellence EXPERTISSUES (NMP3-CT-2004-500283); Interreg III Project Proteus (SP1P151/03); Xunta de Galicia (Consolidación 2006/12); Axudas para adquisición de instrumentación científica 2004, PGIDIT04PXI32201IF; Ángeles Alvariño Program; Universidad de Vigo; Portuguese Foundation for Science and Technology for the PhD grant SFRH/BD/24382/2005.ElsevierUniversidade do MinhoRebollar, EstherCordero, DiegoMartins, AlbinoChiussi, StefanoReis, R. L.Neves, N. M.Leon, Bétty2011-02-152011-02-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/12937eng0169-433210.1016/j.apsusc.2010.12.002http://www.sciencedirect.com/science/article/pii/S016943321001723Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-11T05:08:54Zoai:repositorium.sdum.uminho.pt:1822/12937Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-11T05:08:54Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
title |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
spellingShingle |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation Rebollar, Esther Pore size Femtosecond laser Fiber mesh Electrospinning Laser ablation Science & Technology |
title_short |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
title_full |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
title_fullStr |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
title_full_unstemmed |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
title_sort |
Improvement of electrospun polymer fiber meshes pore size by femtosecond laser irradiation |
author |
Rebollar, Esther |
author_facet |
Rebollar, Esther Cordero, Diego Martins, Albino Chiussi, Stefano Reis, R. L. Neves, N. M. Leon, Bétty |
author_role |
author |
author2 |
Cordero, Diego Martins, Albino Chiussi, Stefano Reis, R. L. Neves, N. M. Leon, Bétty |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Rebollar, Esther Cordero, Diego Martins, Albino Chiussi, Stefano Reis, R. L. Neves, N. M. Leon, Bétty |
dc.subject.por.fl_str_mv |
Pore size Femtosecond laser Fiber mesh Electrospinning Laser ablation Science & Technology |
topic |
Pore size Femtosecond laser Fiber mesh Electrospinning Laser ablation Science & Technology |
description |
Polymer meshes have recently attracted great attention due to their great variety of aplications in fields such as tissue engineering and drug delivery. Poly( -caprolactone) nanofibers were prepared by electrospinning giving rise to porous meshes. However, for some applications in tissue engineering where, for instance, cell migration into the inner regions of the mesh is aimed, the pore size obtained by conventional techniques is too narrow. To improve the pore size, laser irradiation with femtosecond pulses (i.e., negligible heat diffusion into the polymer material and confined excitation energy) is performed. A detailed study of the influence of the pulse energy, pulse length, and number of pulses on the topography of electrospun fiber meshes has been carried out, and the irradiated areas have been studied by scanning electron microscopy, contact angle measurements and spectroscopic techniques. The results show that using the optimal laser parameters, micropores are formed and the nature of the fibers is preserved. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-02-15 2011-02-15T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/12937 |
url |
http://hdl.handle.net/1822/12937 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0169-4332 10.1016/j.apsusc.2010.12.002 http://www.sciencedirect.com/science/article/pii/S016943321001723X |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
_version_ |
1817544531036340224 |