Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications
Main Author: | |
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Publication Date: | 2003 |
Other Authors: | , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Download full: | https://hdl.handle.net/1822/3932 |
Summary: | This work reports on the development and characterization of novel meltable polymers and composites based on casein and soybean proteins. The effects of inert (Al(2)O(3)) and bioactive (tricalcium phosphate) ceramic reinforcements over the mechanical performance, water absorption, and ioactivity behavior of the injection-molded thermoplastics were examined. It was possible to obtain materials and composites with a range of mechanical properties, which might allow for their application in the biomedical field. The incorporation of tricalcium phosphate into the soybean thermoplastic decreased its mechanical properties but lead to the nucleation of a bioactive calcium-phosphate film on their surface when immersed in a simulated body fluid solution. When compounded with 1% of a zirconate coupling agent, the nucleation and growth of the bioactive films on the surface of the referred to composites was accelerated. The materials degradation was studied for ageing periods up to 60 days in an isotonic saline solution. Both water uptake and weight loss were monitored as a function of the immersion time. After 1 month of immersion, the materials showed signal of chemical degradation, presenting weight losses up to 30%. However, further improvement on the mechanical performance and the enhancement of the hydrolytic stability of those materials will be highly necessary for applications in the biomedical field |
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Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applicationsSoybeanCaseinThermoplastic proteinsBiomaterialsBiodegradable polymersDegradationBioactivityScience & TechnologyThis work reports on the development and characterization of novel meltable polymers and composites based on casein and soybean proteins. The effects of inert (Al(2)O(3)) and bioactive (tricalcium phosphate) ceramic reinforcements over the mechanical performance, water absorption, and ioactivity behavior of the injection-molded thermoplastics were examined. It was possible to obtain materials and composites with a range of mechanical properties, which might allow for their application in the biomedical field. The incorporation of tricalcium phosphate into the soybean thermoplastic decreased its mechanical properties but lead to the nucleation of a bioactive calcium-phosphate film on their surface when immersed in a simulated body fluid solution. When compounded with 1% of a zirconate coupling agent, the nucleation and growth of the bioactive films on the surface of the referred to composites was accelerated. The materials degradation was studied for ageing periods up to 60 days in an isotonic saline solution. Both water uptake and weight loss were monitored as a function of the immersion time. After 1 month of immersion, the materials showed signal of chemical degradation, presenting weight losses up to 30%. However, further improvement on the mechanical performance and the enhancement of the hydrolytic stability of those materials will be highly necessary for applications in the biomedical fieldPortuguese Foundation for Science and Tecnology (FCT), Ministry of Science and Tehnology, PortugalWileyUniversidade do MinhoVaz, C. M.Fossen, M.Tuil, R. F. vanGraaf, L. A. deCunha, A. M.Reis, R. L.2003-042003-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/3932eng"Journal Biomedical Materials Research: Part A". ISSN 1549-3296. 65:1 (Apr.2003) 60-70.1549-329610.1002/jbm.a.1041612635155info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:27:29Zoai:repositorium.sdum.uminho.pt:1822/3932Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:22:05.679609Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
title |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
spellingShingle |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications Vaz, C. M. Soybean Casein Thermoplastic proteins Biomaterials Biodegradable polymers Degradation Bioactivity Science & Technology |
title_short |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
title_full |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
title_fullStr |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
title_full_unstemmed |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
title_sort |
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications |
author |
Vaz, C. M. |
author_facet |
Vaz, C. M. Fossen, M. Tuil, R. F. van Graaf, L. A. de Cunha, A. M. Reis, R. L. |
author_role |
author |
author2 |
Fossen, M. Tuil, R. F. van Graaf, L. A. de Cunha, A. M. Reis, R. L. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Vaz, C. M. Fossen, M. Tuil, R. F. van Graaf, L. A. de Cunha, A. M. Reis, R. L. |
dc.subject.por.fl_str_mv |
Soybean Casein Thermoplastic proteins Biomaterials Biodegradable polymers Degradation Bioactivity Science & Technology |
topic |
Soybean Casein Thermoplastic proteins Biomaterials Biodegradable polymers Degradation Bioactivity Science & Technology |
description |
This work reports on the development and characterization of novel meltable polymers and composites based on casein and soybean proteins. The effects of inert (Al(2)O(3)) and bioactive (tricalcium phosphate) ceramic reinforcements over the mechanical performance, water absorption, and ioactivity behavior of the injection-molded thermoplastics were examined. It was possible to obtain materials and composites with a range of mechanical properties, which might allow for their application in the biomedical field. The incorporation of tricalcium phosphate into the soybean thermoplastic decreased its mechanical properties but lead to the nucleation of a bioactive calcium-phosphate film on their surface when immersed in a simulated body fluid solution. When compounded with 1% of a zirconate coupling agent, the nucleation and growth of the bioactive films on the surface of the referred to composites was accelerated. The materials degradation was studied for ageing periods up to 60 days in an isotonic saline solution. Both water uptake and weight loss were monitored as a function of the immersion time. After 1 month of immersion, the materials showed signal of chemical degradation, presenting weight losses up to 30%. However, further improvement on the mechanical performance and the enhancement of the hydrolytic stability of those materials will be highly necessary for applications in the biomedical field |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-04 2003-04-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/3932 |
url |
https://hdl.handle.net/1822/3932 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
"Journal Biomedical Materials Research: Part A". ISSN 1549-3296. 65:1 (Apr.2003) 60-70. 1549-3296 10.1002/jbm.a.10416 12635155 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132690000117760 |