A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/145143 |
Resumo: | Funding Information: The full list of members of the COVIP study group can be found in the accompanying Supplementary Table 1. Funding Open Access funding enabled and organized by Projekt DEAL. No (industry) sponsorship has been received for this investigator-initiated study. |
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A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systemsGeneralFunding Information: The full list of members of the COVIP study group can be found in the accompanying Supplementary Table 1. Funding Open Access funding enabled and organized by Projekt DEAL. No (industry) sponsorship has been received for this investigator-initiated study.In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in intensive care units in a THS or SHI. Retrospective cohort study. 2406 (THS n = 886; SHI n = 1520) critically ill ≥ 70 years patients in 129 ICUs. Generalized estimation equations with robust standard errors were chosen to create population average adjusted odds ratios (aOR). Data were adjusted for patient-specific variables, organ support and health economic data. The primary outcome was 30-day-mortality. Numerical differences between SHI and THS in SOFA scores (6 ± 3 vs. 5 ± 3; p = 0.002) were observed, but clinical frailty scores were similar (> 4; 17% vs. 14%; p = 0.09). Higher rates of renal replacement therapy (18% vs. 11%; p < 0.001) were found in SHI (aOR 0.61 95%CI 0.40–0.92; p = 0.02). No differences regarding intubation rates (68% vs. 70%; p = 0.33), vasopressor use (67% vs. 67%; p = 0.90) and 30-day-mortality rates (47% vs. 50%; p = 0.16) were found. Mortality remained similar between both systems after multivariable adjustment and sensitivity analyses. The retrospective character of this study. Baseline risk and mortality rates were similar between SHI and THS. The type of health care system does not appear to have played a role in the intensive care treatment of critically ill patients ≥ 70 years with COVID-19 in Europe.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNWernly, BernhardFlaatten, HansBeil, MichaelFjølner, JesperBruno, Raphael RomanoArtigas, AntonioPinto, Bernardo BollenSchefold, Joerg C.Kelm, MalteSigal, Svirivan Heerden, Peter VernonSzczeklik, WojciechElhadi, MuhammedJoannidis, MichaelRezar, RichardOeyen, SandraWolff, GeorgMarsh, BrianAndersen, Finn H.Moreno, RuiWernly, SarahLeaver, SusannahBoumendil, ArianeDe Lange, Dylan W.Guidet, BertrandPerings, StefanJung, Christian2022-10-31T23:41:53Z2022-10-122022-10-12T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/145143eng2045-2322PURE: 47463604https://doi.org/10.1038/s41598-022-21580-yinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-22T18:06:19Zoai:run.unl.pt:10362/145143Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-22T18:06:19Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| title |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| spellingShingle |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems Wernly, Bernhard General |
| title_short |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| title_full |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| title_fullStr |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| title_full_unstemmed |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| title_sort |
A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems |
| author |
Wernly, Bernhard |
| author_facet |
Wernly, Bernhard Flaatten, Hans Beil, Michael Fjølner, Jesper Bruno, Raphael Romano Artigas, Antonio Pinto, Bernardo Bollen Schefold, Joerg C. Kelm, Malte Sigal, Sviri van Heerden, Peter Vernon Szczeklik, Wojciech Elhadi, Muhammed Joannidis, Michael Rezar, Richard Oeyen, Sandra Wolff, Georg Marsh, Brian Andersen, Finn H. Moreno, Rui Wernly, Sarah Leaver, Susannah Boumendil, Ariane De Lange, Dylan W. Guidet, Bertrand Perings, Stefan Jung, Christian |
| author_role |
author |
| author2 |
Flaatten, Hans Beil, Michael Fjølner, Jesper Bruno, Raphael Romano Artigas, Antonio Pinto, Bernardo Bollen Schefold, Joerg C. Kelm, Malte Sigal, Sviri van Heerden, Peter Vernon Szczeklik, Wojciech Elhadi, Muhammed Joannidis, Michael Rezar, Richard Oeyen, Sandra Wolff, Georg Marsh, Brian Andersen, Finn H. Moreno, Rui Wernly, Sarah Leaver, Susannah Boumendil, Ariane De Lange, Dylan W. Guidet, Bertrand Perings, Stefan Jung, Christian |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
| dc.contributor.author.fl_str_mv |
Wernly, Bernhard Flaatten, Hans Beil, Michael Fjølner, Jesper Bruno, Raphael Romano Artigas, Antonio Pinto, Bernardo Bollen Schefold, Joerg C. Kelm, Malte Sigal, Sviri van Heerden, Peter Vernon Szczeklik, Wojciech Elhadi, Muhammed Joannidis, Michael Rezar, Richard Oeyen, Sandra Wolff, Georg Marsh, Brian Andersen, Finn H. Moreno, Rui Wernly, Sarah Leaver, Susannah Boumendil, Ariane De Lange, Dylan W. Guidet, Bertrand Perings, Stefan Jung, Christian |
| dc.subject.por.fl_str_mv |
General |
| topic |
General |
| description |
Funding Information: The full list of members of the COVIP study group can be found in the accompanying Supplementary Table 1. Funding Open Access funding enabled and organized by Projekt DEAL. No (industry) sponsorship has been received for this investigator-initiated study. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-10-31T23:41:53Z 2022-10-12 2022-10-12T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/145143 |
| url |
http://hdl.handle.net/10362/145143 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
2045-2322 PURE: 47463604 https://doi.org/10.1038/s41598-022-21580-y |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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mluisa.alvim@gmail.com |
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1817545895979253760 |