Blocking the receptor for interleukin 10 protects mice from lethal listeriosis

Detalhes bibliográficos
Autor(a) principal: Silva, RA
Data de Publicação: 2001
Outros Autores: Appelberg, R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/76102
Resumo: High doses of Listeria monocytogenes overcome the ability of a normal mouse to control the infection, due to massive bacterial replication. Treatment with an anti-interleukin 10 (IL-10) receptor monoclonal antibody prevented the fatal course of infection with high doses of bacteria. This work shows that blocking the receptor for IL-10 may have useful therapeutic applications.
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spelling Blocking the receptor for interleukin 10 protects mice from lethal listeriosisInfecções, Medicina básicaInfections, Basic medicineHigh doses of Listeria monocytogenes overcome the ability of a normal mouse to control the infection, due to massive bacterial replication. Treatment with an anti-interleukin 10 (IL-10) receptor monoclonal antibody prevented the fatal course of infection with high doses of bacteria. This work shows that blocking the receptor for IL-10 may have useful therapeutic applications.20012001-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/octet-streamhttps://hdl.handle.net/10216/76102eng0066-480410.1128/aac.45.4.1312-1314.2001Silva, RAAppelberg, Rinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:55:32Zoai:repositorio-aberto.up.pt:10216/76102Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:11:41.987877Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
title Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
spellingShingle Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
Silva, RA
Infecções, Medicina básica
Infections, Basic medicine
title_short Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
title_full Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
title_fullStr Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
title_full_unstemmed Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
title_sort Blocking the receptor for interleukin 10 protects mice from lethal listeriosis
author Silva, RA
author_facet Silva, RA
Appelberg, R
author_role author
author2 Appelberg, R
author2_role author
dc.contributor.author.fl_str_mv Silva, RA
Appelberg, R
dc.subject.por.fl_str_mv Infecções, Medicina básica
Infections, Basic medicine
topic Infecções, Medicina básica
Infections, Basic medicine
description High doses of Listeria monocytogenes overcome the ability of a normal mouse to control the infection, due to massive bacterial replication. Treatment with an anti-interleukin 10 (IL-10) receptor monoclonal antibody prevented the fatal course of infection with high doses of bacteria. This work shows that blocking the receptor for IL-10 may have useful therapeutic applications.
publishDate 2001
dc.date.none.fl_str_mv 2001
2001-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/76102
url https://hdl.handle.net/10216/76102
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0066-4804
10.1128/aac.45.4.1312-1314.2001
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eu_rights_str_mv openAccess
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