Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/14957 |
Resumo: | The dissemination of the dengue virus (DENV) in endemic regions with HIV is a public health concern with greater importance when there is evidence of vertical transmission of DENV during pregnancy. Herein, we investigated DENV among HIV-infected pregnant women in Luanda, the capital city of Angola. This was part of a cross-sectional study carried out on 42 pregnant women newly diagnosed with HIV. A total of 36 plasma samples from the 42 HIV-positive pregnant women were screened for DENV using RT‐PCR and ELISA. None of the specimens tested positive for DENV by RT-PCR. Regarding seroprevalence, 94.4% of the samples were positive for IgG and 11.1% for IgM. Recent infection (IgG-/IgM+ or IgG+/IgM+) was detected in 11.1% of the samples and past infection (IgG+/IgM-) in 83.3%. The risk of recent infection was higher in pregnant women over 25 years of age [OR: 13.0 (95% CI: 1.14-148), p=0.039]. Our study showed laboratory evidence of a recent DENV infection among HIV-infected pregnant women attending antenatal care in Luanda. Our findings provide critical data regarding DENV infection among HIV-infected pregnant women in Luanda. Future studies involving a larger sample size of HIV-infected pregnant women are necessary to support ongoing public health programs to combat arboviruses in Angola. |
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Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concernDengue virusHIV infectionSeroprevalencePregnant womenAngolaLuandaThe dissemination of the dengue virus (DENV) in endemic regions with HIV is a public health concern with greater importance when there is evidence of vertical transmission of DENV during pregnancy. Herein, we investigated DENV among HIV-infected pregnant women in Luanda, the capital city of Angola. This was part of a cross-sectional study carried out on 42 pregnant women newly diagnosed with HIV. A total of 36 plasma samples from the 42 HIV-positive pregnant women were screened for DENV using RT‐PCR and ELISA. None of the specimens tested positive for DENV by RT-PCR. Regarding seroprevalence, 94.4% of the samples were positive for IgG and 11.1% for IgM. Recent infection (IgG-/IgM+ or IgG+/IgM+) was detected in 11.1% of the samples and past infection (IgG+/IgM-) in 83.3%. The risk of recent infection was higher in pregnant women over 25 years of age [OR: 13.0 (95% CI: 1.14-148), p=0.039]. Our study showed laboratory evidence of a recent DENV infection among HIV-infected pregnant women attending antenatal care in Luanda. Our findings provide critical data regarding DENV infection among HIV-infected pregnant women in Luanda. Future studies involving a larger sample size of HIV-infected pregnant women are necessary to support ongoing public health programs to combat arboviruses in Angola.RCIPLSebastião, Cruz S.Neto, ZoraimaJandondo, DomingosMirandela, MarinelaMorais, JoanaBrito, Miguel2022-09-08T14:44:47Z2022-082022-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/14957engSebastião CS, Neto Z, Jandondo D, Mirandela M, Morais J, Brito M. Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern. Sci Afr. 2022;17:e01356.10.1016/j.sciaf.2022.e01356info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:11:48Zoai:repositorio.ipl.pt:10400.21/14957Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:22:42.823922Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
title |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
spellingShingle |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern Sebastião, Cruz S. Dengue virus HIV infection Seroprevalence Pregnant women Angola Luanda |
title_short |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
title_full |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
title_fullStr |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
title_full_unstemmed |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
title_sort |
Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern |
author |
Sebastião, Cruz S. |
author_facet |
Sebastião, Cruz S. Neto, Zoraima Jandondo, Domingos Mirandela, Marinela Morais, Joana Brito, Miguel |
author_role |
author |
author2 |
Neto, Zoraima Jandondo, Domingos Mirandela, Marinela Morais, Joana Brito, Miguel |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Sebastião, Cruz S. Neto, Zoraima Jandondo, Domingos Mirandela, Marinela Morais, Joana Brito, Miguel |
dc.subject.por.fl_str_mv |
Dengue virus HIV infection Seroprevalence Pregnant women Angola Luanda |
topic |
Dengue virus HIV infection Seroprevalence Pregnant women Angola Luanda |
description |
The dissemination of the dengue virus (DENV) in endemic regions with HIV is a public health concern with greater importance when there is evidence of vertical transmission of DENV during pregnancy. Herein, we investigated DENV among HIV-infected pregnant women in Luanda, the capital city of Angola. This was part of a cross-sectional study carried out on 42 pregnant women newly diagnosed with HIV. A total of 36 plasma samples from the 42 HIV-positive pregnant women were screened for DENV using RT‐PCR and ELISA. None of the specimens tested positive for DENV by RT-PCR. Regarding seroprevalence, 94.4% of the samples were positive for IgG and 11.1% for IgM. Recent infection (IgG-/IgM+ or IgG+/IgM+) was detected in 11.1% of the samples and past infection (IgG+/IgM-) in 83.3%. The risk of recent infection was higher in pregnant women over 25 years of age [OR: 13.0 (95% CI: 1.14-148), p=0.039]. Our study showed laboratory evidence of a recent DENV infection among HIV-infected pregnant women attending antenatal care in Luanda. Our findings provide critical data regarding DENV infection among HIV-infected pregnant women in Luanda. Future studies involving a larger sample size of HIV-infected pregnant women are necessary to support ongoing public health programs to combat arboviruses in Angola. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-08T14:44:47Z 2022-08 2022-08-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/14957 |
url |
http://hdl.handle.net/10400.21/14957 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Sebastião CS, Neto Z, Jandondo D, Mirandela M, Morais J, Brito M. Dengue virus among HIV-infected pregnant women attending antenatal care in Luanda, Angola: an emerging public health concern. Sci Afr. 2022;17:e01356. 10.1016/j.sciaf.2022.e01356 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133499448360960 |