Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation

Detalhes bibliográficos
Autor(a) principal: Rebelo Gomes, Inês
Data de Publicação: 2018
Outros Autores: Cardoso, José Carlos, Tellechea, Óscar
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.76.1.857
Resumo: Introduction: Dermoscopy is an in vivo, non-invasive technique that is widely used as a complementary method for the study of pigmented skin lesions and enables the early diagnosis of cutaneous melanoma. The purpose of the present study is to evaluate the diagnostic accuracy of dermoscopy and to extend the dermoscopy-histopatholoy correlations.Methods: Retrospective study using the database of the Dermoscopy and Pigmented Lesions Clinic and the database of the Histology of the Dermatology Department of CHUC. Each melanocytic lesion was evaluated according to multiple dermoscopic and histopathological parameters. The agreement between diagnoses and between the evaluated parameters was determined.Results: The malignant/benign ratio was 1:9.2. The agreement between the dermoscopic and histologic diagnoses was fair. The agreement for melanoma was excellent and dermoscopy showed 92.9% sensitivity and 96.9% specificity for this diagnosis. There was agreement between a reticular pattern and the presence of bridging of rete ridges and cytological atypia; globular pattern and the presence of nests; atypical network and presence of fibrosis and cytological atypia; blotches and pigmented parakeratosis; blue-whitish veil and fibrosis.Conclusion: In spite of some limitations and unexpected findings, many of the results of the present study are concordant with the literature, showing a high sensitivity and specificity of dermoscopy in the diagnosis of melanoma, which results in improvement in early diagnosis without increasing the total number of excisions of pigmented lesions.
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spelling Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological CorrelationAcuidade Diagnóstica da Dermatoscopia em Lesões Melanocíticas: Estudo Retrospetivo com Correlação Histológica.DermoscopyDiagnosisDifferentialHistologyMelanocytesMelanomaNevusSkin NeoplasmsDermatoscopiaDiagnóstico DiferencialHistologiaMelanócitosMelanomaNeoplasias da PeleNevoIntroduction: Dermoscopy is an in vivo, non-invasive technique that is widely used as a complementary method for the study of pigmented skin lesions and enables the early diagnosis of cutaneous melanoma. The purpose of the present study is to evaluate the diagnostic accuracy of dermoscopy and to extend the dermoscopy-histopatholoy correlations.Methods: Retrospective study using the database of the Dermoscopy and Pigmented Lesions Clinic and the database of the Histology of the Dermatology Department of CHUC. Each melanocytic lesion was evaluated according to multiple dermoscopic and histopathological parameters. The agreement between diagnoses and between the evaluated parameters was determined.Results: The malignant/benign ratio was 1:9.2. The agreement between the dermoscopic and histologic diagnoses was fair. The agreement for melanoma was excellent and dermoscopy showed 92.9% sensitivity and 96.9% specificity for this diagnosis. There was agreement between a reticular pattern and the presence of bridging of rete ridges and cytological atypia; globular pattern and the presence of nests; atypical network and presence of fibrosis and cytological atypia; blotches and pigmented parakeratosis; blue-whitish veil and fibrosis.Conclusion: In spite of some limitations and unexpected findings, many of the results of the present study are concordant with the literature, showing a high sensitivity and specificity of dermoscopy in the diagnosis of melanoma, which results in improvement in early diagnosis without increasing the total number of excisions of pigmented lesions.Introdução: A dermatoscopia é uma técnica in vivo não-invasiva, amplamente usada como ferramenta complementar no estudo de lesões pigmentadas da pele, permitindo um diagnóstico mais precoce do melanoma cutâneo. O objetivo deste estudo é avaliar a acuidade diagnóstica da dermatoscopia em lesões melanocíticas e alargar as correlações dermatoscopia-histopatologia já estabelecidas.Material e Métodos: Estudo retrospetivo utilizando a base de dados da Consulta de Dermatoscopia e Lesões Pigmentadas e a base de dados da Histologia de um Serviço de Dermatologia. Cada lesão melanocítica foi avaliada segundo parâmetros dermatoscópicos e histológicos. Determinou-se a concordância entre os diagnósticos e entre os parâmetros avaliados.Resultados: Verificou-se um ratio maligno/benigno de 1:9,2. Obteve-se uma concordância razoável entre os diagnósticos dermatoscópicos e histológicos. Para os melanomas obteve-se uma concordância excelente, tendo a dermatoscopia revelado uma sensibilidade de 92,9% e especificidade de 96,9%. Observou-se concordância entre padrão reticular e a presença de fusão de cristas e atipia citológica; padrão globular e presença de tecas; rede atípica e a presença de fibrose e atipia citológica; blotches e paraqueratose pigmentada; véu azul esbranquiçado e a presença de fibrose.Conclusão: Apesar de algumas limitações e achados não esperados, muitos dos resultados do presente estudo vêm na continuidade do que tem vindo a ser descrito na literatura, mostrando uma elevada sensibilidade e especificidade da dermatoscopia no diagnóstico de melanoma, o que se reflete numa otimização do diagnóstico precoce sem necessidade de aumento do número total de excisões de lesões pigmentadas.Sociedade Portuguesa de Dermatologia e Venereologia2018-04-05T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.76.1.857oai:ojs.revista.spdv.com.pt:article/857Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 1 (2018): Janeiro - Março; 37-46Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 1 (2018): Janeiro - Março; 37-462182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/857https://doi.org/10.29021/spdv.76.1.857https://revista.spdv.com.pt/index.php/spdv/article/view/857/546Rebelo Gomes, InêsCardoso, José CarlosTellechea, Óscarinfo:eu-repo/semantics/openAccess2022-10-06T12:35:06Zoai:ojs.revista.spdv.com.pt:article/857Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:05.058475Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
Acuidade Diagnóstica da Dermatoscopia em Lesões Melanocíticas: Estudo Retrospetivo com Correlação Histológica.
title Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
spellingShingle Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
Rebelo Gomes, Inês
Dermoscopy
Diagnosis
Differential
Histology
Melanocytes
Melanoma
Nevus
Skin Neoplasms
Dermatoscopia
Diagnóstico Diferencial
Histologia
Melanócitos
Melanoma
Neoplasias da Pele
Nevo
title_short Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
title_full Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
title_fullStr Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
title_full_unstemmed Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
title_sort Diagnostic Accuracy of Dermoscopy in Melanocytic Lesions: Retrospective Study with Histological Correlation
author Rebelo Gomes, Inês
author_facet Rebelo Gomes, Inês
Cardoso, José Carlos
Tellechea, Óscar
author_role author
author2 Cardoso, José Carlos
Tellechea, Óscar
author2_role author
author
dc.contributor.author.fl_str_mv Rebelo Gomes, Inês
Cardoso, José Carlos
Tellechea, Óscar
dc.subject.por.fl_str_mv Dermoscopy
Diagnosis
Differential
Histology
Melanocytes
Melanoma
Nevus
Skin Neoplasms
Dermatoscopia
Diagnóstico Diferencial
Histologia
Melanócitos
Melanoma
Neoplasias da Pele
Nevo
topic Dermoscopy
Diagnosis
Differential
Histology
Melanocytes
Melanoma
Nevus
Skin Neoplasms
Dermatoscopia
Diagnóstico Diferencial
Histologia
Melanócitos
Melanoma
Neoplasias da Pele
Nevo
description Introduction: Dermoscopy is an in vivo, non-invasive technique that is widely used as a complementary method for the study of pigmented skin lesions and enables the early diagnosis of cutaneous melanoma. The purpose of the present study is to evaluate the diagnostic accuracy of dermoscopy and to extend the dermoscopy-histopatholoy correlations.Methods: Retrospective study using the database of the Dermoscopy and Pigmented Lesions Clinic and the database of the Histology of the Dermatology Department of CHUC. Each melanocytic lesion was evaluated according to multiple dermoscopic and histopathological parameters. The agreement between diagnoses and between the evaluated parameters was determined.Results: The malignant/benign ratio was 1:9.2. The agreement between the dermoscopic and histologic diagnoses was fair. The agreement for melanoma was excellent and dermoscopy showed 92.9% sensitivity and 96.9% specificity for this diagnosis. There was agreement between a reticular pattern and the presence of bridging of rete ridges and cytological atypia; globular pattern and the presence of nests; atypical network and presence of fibrosis and cytological atypia; blotches and pigmented parakeratosis; blue-whitish veil and fibrosis.Conclusion: In spite of some limitations and unexpected findings, many of the results of the present study are concordant with the literature, showing a high sensitivity and specificity of dermoscopy in the diagnosis of melanoma, which results in improvement in early diagnosis without increasing the total number of excisions of pigmented lesions.
publishDate 2018
dc.date.none.fl_str_mv 2018-04-05T00:00:00Z
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.76.1.857
oai:ojs.revista.spdv.com.pt:article/857
url https://doi.org/10.29021/spdv.76.1.857
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/857
https://doi.org/10.29021/spdv.76.1.857
https://revista.spdv.com.pt/index.php/spdv/article/view/857/546
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 1 (2018): Janeiro - Março; 37-46
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 1 (2018): Janeiro - Março; 37-46
2182-2409
2182-2395
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