Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/8536 |
Resumo: | Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34981750/ |
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Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomesIodineNeonatal OutcomesNewbornObstetric OutcomesPregnancyDoenças GenéticasFree PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34981750/Objectives: Over 1.9 billion people worldwide are living in areas estimated to be iodine insufficient. Strategies for iodine supplementation include campaigns targeting vulnerable groups, such as women in pre-conception, pregnancy and lactation. Portuguese women of childbearing age and pregnant women were shown to be mildly-to-moderately iodine deficient. As a response, in 2013, the National Health Authority (NHA) issued a recommendation that all women considering pregnancy, pregnant or breastfeeding, take a daily supplement of 150-200 μg iodine. This study explored how the iodine supplementation recommendation has been fulfilled among pregnant and lactating women in Portugal, and whether the reported iodine supplements intake impacted on adverse obstetric and neonatal outcomes. Design and methods: Observational retrospective study on pregnant women who delivered or had a fetal loss in the Braga Hospital and had their pregnancies followed in Family Health Units. Results: The use of iodine supplements increased from 25% before the recommendation to 81% after the recommendation. This was mostly due to an increase in the use of supplements containing iodine only. Iodine supplementation was protective for the number of adverse obstetric outcomes (odds ratio (OR) = 0.791, P = 0.018) and for neonatal morbidities (OR = 0.528, P = 0.024) after controlling for relevant confounding variables. Conclusion: The recommendation seems to have succeeded in implementing iodine supplementation during pregnancy. National prospective studies are now needed to evaluate the impact of iodine supplementation on maternal thyroid homeostasis and offspring psychomotor development and on whether the time of the beginning of iodine supplementation (how early during preconception or pregnancy) is relevant to consider.This work has been funded by National funds, through the Foundation for Science and Technology (FCT) – project UIDB/50026/2020 and UIDP/50026/2020 and by the project NORTE-01-0145-FEDER-000039, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). Funding agencies did not participate in any part of the research or in data or manuscript preparationBioScientificaRepositório Científico do Instituto Nacional de SaúdeLopes-Pereira, MariaQuialheiro, AnnaCosta, PatrícioRoque, SusanaCorreia Santos, NadineCorreia-Neves, MargaridaGoios, AnaCarvalho, IvoneKorevaar, Tim I.M.Vilarinho, LauraPalha, Joana Almeida2023-02-28T12:45:33Z2022-01-012022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8536engEur Thyroid J. 2022 Jan 1;11(1):e210035. doi: 10.1530/ETJ-21-00352235-080210.1530/ETJ-21-0035info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:37Zoai:repositorio.insa.pt:10400.18/8536Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:10.695822Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| title |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| spellingShingle |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes Lopes-Pereira, Maria Iodine Neonatal Outcomes Newborn Obstetric Outcomes Pregnancy Doenças Genéticas |
| title_short |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| title_full |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| title_fullStr |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| title_full_unstemmed |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| title_sort |
Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes |
| author |
Lopes-Pereira, Maria |
| author_facet |
Lopes-Pereira, Maria Quialheiro, Anna Costa, Patrício Roque, Susana Correia Santos, Nadine Correia-Neves, Margarida Goios, Ana Carvalho, Ivone Korevaar, Tim I.M. Vilarinho, Laura Palha, Joana Almeida |
| author_role |
author |
| author2 |
Quialheiro, Anna Costa, Patrício Roque, Susana Correia Santos, Nadine Correia-Neves, Margarida Goios, Ana Carvalho, Ivone Korevaar, Tim I.M. Vilarinho, Laura Palha, Joana Almeida |
| author2_role |
author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Lopes-Pereira, Maria Quialheiro, Anna Costa, Patrício Roque, Susana Correia Santos, Nadine Correia-Neves, Margarida Goios, Ana Carvalho, Ivone Korevaar, Tim I.M. Vilarinho, Laura Palha, Joana Almeida |
| dc.subject.por.fl_str_mv |
Iodine Neonatal Outcomes Newborn Obstetric Outcomes Pregnancy Doenças Genéticas |
| topic |
Iodine Neonatal Outcomes Newborn Obstetric Outcomes Pregnancy Doenças Genéticas |
| description |
Free PMC article: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34981750/ |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-01-01 2022-01-01T00:00:00Z 2023-02-28T12:45:33Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/8536 |
| url |
http://hdl.handle.net/10400.18/8536 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Eur Thyroid J. 2022 Jan 1;11(1):e210035. doi: 10.1530/ETJ-21-0035 2235-0802 10.1530/ETJ-21-0035 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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BioScientifica |
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BioScientifica |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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