Functionalized nanoparticles for intracellular drug delivery and cell-tracking

Detalhes bibliográficos
Autor(a) principal: Oliveira, Joaquim M.
Data de Publicação: 2014
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/30684
Resumo: Cell- and tissue-engineering have greatly benefited from huge developments on the nanotechnology field. Important achievements include not only the increasing number of nanoparticles (NP’s) that have synthesized but also from the innumerous possibilities for tuning its biological and physicochemical properties by means of surface engineering. Our group has been proposing the functionalization and coating of different nanosystems (e.g. dendrimer-based NP’s and gold nanorods) as a strategy to improve biocompatibility, enhance NP’s uptake by cells and intracellular drug release, and allow investigating cell fate. The developed surface engineering strategies represent the future of therapeutic approaches envisioning the control of stem cells functions in vitro and in vivo, which can open new possibilities for treating different neurodegenerative and musculoskeletal diseases/disabilities.
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spelling Functionalized nanoparticles for intracellular drug delivery and cell-trackingBiomedical applicationsNanosystemsTop down fabricationCell- and tissue-engineering have greatly benefited from huge developments on the nanotechnology field. Important achievements include not only the increasing number of nanoparticles (NP’s) that have synthesized but also from the innumerous possibilities for tuning its biological and physicochemical properties by means of surface engineering. Our group has been proposing the functionalization and coating of different nanosystems (e.g. dendrimer-based NP’s and gold nanorods) as a strategy to improve biocompatibility, enhance NP’s uptake by cells and intracellular drug release, and allow investigating cell fate. The developed surface engineering strategies represent the future of therapeutic approaches envisioning the control of stem cells functions in vitro and in vivo, which can open new possibilities for treating different neurodegenerative and musculoskeletal diseases/disabilities.Universidade do MinhoOliveira, Joaquim M.2014-102014-10-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/30684engOliveira J. M. Functionalized nanoparticles for intracellular drug delivery and cell-tracking, Polaris 2nd Workshop, 2014http://www.termstem.org/sites/default/files/POLARIS%202nd%20Workshop%20Scientific%20Program_0.pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-11T06:14:48Zoai:repositorium.sdum.uminho.pt:1822/30684Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-11T06:14:48Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Functionalized nanoparticles for intracellular drug delivery and cell-tracking
title Functionalized nanoparticles for intracellular drug delivery and cell-tracking
spellingShingle Functionalized nanoparticles for intracellular drug delivery and cell-tracking
Oliveira, Joaquim M.
Biomedical applications
Nanosystems
Top down fabrication
title_short Functionalized nanoparticles for intracellular drug delivery and cell-tracking
title_full Functionalized nanoparticles for intracellular drug delivery and cell-tracking
title_fullStr Functionalized nanoparticles for intracellular drug delivery and cell-tracking
title_full_unstemmed Functionalized nanoparticles for intracellular drug delivery and cell-tracking
title_sort Functionalized nanoparticles for intracellular drug delivery and cell-tracking
author Oliveira, Joaquim M.
author_facet Oliveira, Joaquim M.
author_role author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Oliveira, Joaquim M.
dc.subject.por.fl_str_mv Biomedical applications
Nanosystems
Top down fabrication
topic Biomedical applications
Nanosystems
Top down fabrication
description Cell- and tissue-engineering have greatly benefited from huge developments on the nanotechnology field. Important achievements include not only the increasing number of nanoparticles (NP’s) that have synthesized but also from the innumerous possibilities for tuning its biological and physicochemical properties by means of surface engineering. Our group has been proposing the functionalization and coating of different nanosystems (e.g. dendrimer-based NP’s and gold nanorods) as a strategy to improve biocompatibility, enhance NP’s uptake by cells and intracellular drug release, and allow investigating cell fate. The developed surface engineering strategies represent the future of therapeutic approaches envisioning the control of stem cells functions in vitro and in vivo, which can open new possibilities for treating different neurodegenerative and musculoskeletal diseases/disabilities.
publishDate 2014
dc.date.none.fl_str_mv 2014-10
2014-10-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/30684
url http://hdl.handle.net/1822/30684
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Oliveira J. M. Functionalized nanoparticles for intracellular drug delivery and cell-tracking, Polaris 2nd Workshop, 2014
http://www.termstem.org/sites/default/files/POLARIS%202nd%20Workshop%20Scientific%20Program_0.pdf
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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