The Importance of Autopsy in Early Neonatal Death in Portugal
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182 |
Resumo: | Introduction: The early neonatal period is the most critical for the newborn’s life. The autopsy is important to understand the cause of death, and find other diagnoses not clinically identified. However, the rate of neonatal autopsy is declining worldwide. This study aims to characterize early neonatal death and the clinical importance of the autopsy, evaluating the concordance between clinical and pathological diagnosis.Material and Methods: Retrospective study of the clinical records of all neonates admitted to a level III Neonatal Intensive Care unit in Portugal who died during the first week of life in 10 consecutive years (2008 – 2017). In order to classify the concordance found between clinical and pathological diagnoses, the modified Goldman classification was used.Results: During the first week of life, 76 newborns died. The main causes of death were complications related with prematurity and congenital malformations. The autopsy was performed in 50 newborns. Additional findings were found in 62% of the cases, and in 12% findings with important implications for genetic counseling of future pregnancies. There was concordance between the clinical and pathological findings in 38% of cases.Discussion: An autopsy was performed more frequently in newborns with greater gestational age. The number of additional diagnoses found at autopsy, including diagnoses with implications for genetic counseling, confirm the importance of performing them.Conclusion: An autopsy should be proposed to all parents after early neonatal death, given its importance in clarifying the cause of death. |
id |
RCAP_a2e7e5850c895dbdb237cb5eca1eecb0 |
---|---|
oai_identifier_str |
oai:ojs.www.actamedicaportuguesa.com:article/12182 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
The Importance of Autopsy in Early Neonatal Death in PortugalA Importância da Autópsia na Morte Neonatal Precoce em PortugalAutopsyCauses of DeathInfant MortalityInfantNewbornNeonatal Intensive Care UnitAutópsiaCausas de MorteMortalidade InfantilRecém-NascidoUnidade de Cuidados Intensivos NeonataisIntroduction: The early neonatal period is the most critical for the newborn’s life. The autopsy is important to understand the cause of death, and find other diagnoses not clinically identified. However, the rate of neonatal autopsy is declining worldwide. This study aims to characterize early neonatal death and the clinical importance of the autopsy, evaluating the concordance between clinical and pathological diagnosis.Material and Methods: Retrospective study of the clinical records of all neonates admitted to a level III Neonatal Intensive Care unit in Portugal who died during the first week of life in 10 consecutive years (2008 – 2017). In order to classify the concordance found between clinical and pathological diagnoses, the modified Goldman classification was used.Results: During the first week of life, 76 newborns died. The main causes of death were complications related with prematurity and congenital malformations. The autopsy was performed in 50 newborns. Additional findings were found in 62% of the cases, and in 12% findings with important implications for genetic counseling of future pregnancies. There was concordance between the clinical and pathological findings in 38% of cases.Discussion: An autopsy was performed more frequently in newborns with greater gestational age. The number of additional diagnoses found at autopsy, including diagnoses with implications for genetic counseling, confirm the importance of performing them.Conclusion: An autopsy should be proposed to all parents after early neonatal death, given its importance in clarifying the cause of death.Introdução: O período neonatal precoce é o mais crítico para a vida do recém-nascido. A autópsia é importante para compreender acausa de morte e conhecer outros diagnósticos não identificados clinicamente. No entanto, a taxa de autópsia neonatal está a diminuir em todo o mundo. Este estudo pretende caracterizar a morte neonatal precoce e a importância clínica da autópsia, avaliando a concordância entre o diagnóstico clínico e o anatomopatológico.Material e Métodos: Estudo retrospetivo dos processos clínicos de todos recém-nascidos admitidos numa unidade de CuidadosIntensivos Neonatais de nível III em Portugal e que faleceram durante a primeira semana de vida em 10 anos consecutivos (2008 - 2017). Para classificar a concordância encontrada entre os diagnósticos clínicos e anatomopatológicos foi usada a classificação de Goldman modificada.Resultados: Na primeira semana de vida faleceram 76 recém-nascidos. As principais causas de morte foram complicações relacionadas com prematuridade e anomalias congénitas. A autópsia foi realizada em 50 (65,8%) recém-nascidos. Achados adicionais foram encontrados em 62% dos casos, sendo em 12% achados com implicações importantes no aconselhamento genético de futuras gestações. A concordância entre os achados clínicos e anatomopatológicos foi de 38% dos casos.Discussão: A autópsia foi realizada com maior frequência em recém-nascidos com maior idade gestacional. O número de diagnósticos adicionais encontrados na autópsia, incluindo diagnósticos com implicações para aconselhamento genético, confirmam a importância da sua realização.Conclusão: A autópsia deve ser proposta a todos os pais após a morte neonatal precoce, dada a sua importância no esclarecimento da causa de morte.Ordem dos Médicos2020-12-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182oai:ojs.www.actamedicaportuguesa.com:article/12182Acta Médica Portuguesa; Vol. 33 No. 12 (2020): December; 811-818Acta Médica Portuguesa; Vol. 33 N.º 12 (2020): Dezembro; 811-8181646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/6113https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/6715https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/11642https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/11643https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/12198Direitos de Autor (c) 2020 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessMiranda, MarleneCosta, SandraSoares, HenriqueBarbosa, JoselinaFlor-de-Lima, FilipaRodrigues, ManuelaGuimarães, Hercília2022-12-20T11:06:32Zoai:ojs.www.actamedicaportuguesa.com:article/12182Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:09.280168Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The Importance of Autopsy in Early Neonatal Death in Portugal A Importância da Autópsia na Morte Neonatal Precoce em Portugal |
title |
The Importance of Autopsy in Early Neonatal Death in Portugal |
spellingShingle |
The Importance of Autopsy in Early Neonatal Death in Portugal Miranda, Marlene Autopsy Causes of Death Infant Mortality Infant Newborn Neonatal Intensive Care Unit Autópsia Causas de Morte Mortalidade Infantil Recém-Nascido Unidade de Cuidados Intensivos Neonatais |
title_short |
The Importance of Autopsy in Early Neonatal Death in Portugal |
title_full |
The Importance of Autopsy in Early Neonatal Death in Portugal |
title_fullStr |
The Importance of Autopsy in Early Neonatal Death in Portugal |
title_full_unstemmed |
The Importance of Autopsy in Early Neonatal Death in Portugal |
title_sort |
The Importance of Autopsy in Early Neonatal Death in Portugal |
author |
Miranda, Marlene |
author_facet |
Miranda, Marlene Costa, Sandra Soares, Henrique Barbosa, Joselina Flor-de-Lima, Filipa Rodrigues, Manuela Guimarães, Hercília |
author_role |
author |
author2 |
Costa, Sandra Soares, Henrique Barbosa, Joselina Flor-de-Lima, Filipa Rodrigues, Manuela Guimarães, Hercília |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Miranda, Marlene Costa, Sandra Soares, Henrique Barbosa, Joselina Flor-de-Lima, Filipa Rodrigues, Manuela Guimarães, Hercília |
dc.subject.por.fl_str_mv |
Autopsy Causes of Death Infant Mortality Infant Newborn Neonatal Intensive Care Unit Autópsia Causas de Morte Mortalidade Infantil Recém-Nascido Unidade de Cuidados Intensivos Neonatais |
topic |
Autopsy Causes of Death Infant Mortality Infant Newborn Neonatal Intensive Care Unit Autópsia Causas de Morte Mortalidade Infantil Recém-Nascido Unidade de Cuidados Intensivos Neonatais |
description |
Introduction: The early neonatal period is the most critical for the newborn’s life. The autopsy is important to understand the cause of death, and find other diagnoses not clinically identified. However, the rate of neonatal autopsy is declining worldwide. This study aims to characterize early neonatal death and the clinical importance of the autopsy, evaluating the concordance between clinical and pathological diagnosis.Material and Methods: Retrospective study of the clinical records of all neonates admitted to a level III Neonatal Intensive Care unit in Portugal who died during the first week of life in 10 consecutive years (2008 – 2017). In order to classify the concordance found between clinical and pathological diagnoses, the modified Goldman classification was used.Results: During the first week of life, 76 newborns died. The main causes of death were complications related with prematurity and congenital malformations. The autopsy was performed in 50 newborns. Additional findings were found in 62% of the cases, and in 12% findings with important implications for genetic counseling of future pregnancies. There was concordance between the clinical and pathological findings in 38% of cases.Discussion: An autopsy was performed more frequently in newborns with greater gestational age. The number of additional diagnoses found at autopsy, including diagnoses with implications for genetic counseling, confirm the importance of performing them.Conclusion: An autopsy should be proposed to all parents after early neonatal death, given its importance in clarifying the cause of death. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182 oai:ojs.www.actamedicaportuguesa.com:article/12182 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/12182 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/6113 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/6715 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/11642 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/11643 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12182/12198 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2020 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2020 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 33 No. 12 (2020): December; 811-818 Acta Médica Portuguesa; Vol. 33 N.º 12 (2020): Dezembro; 811-818 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130650296451072 |