Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4

Detalhes bibliográficos
Autor(a) principal: Mereiter, S
Data de Publicação: 2016
Outros Autores: Magalhães, A, Adamczyk, B, Jin, C, Almeida, A, Drici, L, Ibáñez-Vea, M, Larsen, M, Kolarich, D, Karlsson, N, Reis, CA
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/119044
Resumo: Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two parallel structural analyzes, based on PGC-ESI-MS/MS. Data on glycan structure identification and relative abundance in ST3GAL4 overexpressing cells and respective mock control are presented. The sialoproteomic analysis based on titanium-dioxide enrichment of sialopeptides with subsequent LC-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer" [1].
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spelling Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4Gastric cancerN-glycomeO-glycomeSialoproteomeSialyltransferaseGastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two parallel structural analyzes, based on PGC-ESI-MS/MS. Data on glycan structure identification and relative abundance in ST3GAL4 overexpressing cells and respective mock control are presented. The sialoproteomic analysis based on titanium-dioxide enrichment of sialopeptides with subsequent LC-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer" [1].Elsevier20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/119044eng2352-340910.1016/j.dib.2016.03.022Mereiter, SMagalhães, AAdamczyk, BJin, CAlmeida, ADrici, LIbáñez-Vea, MLarsen, MKolarich, DKarlsson, NReis, CAinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-09-27T08:33:51Zoai:repositorio-aberto.up.pt:10216/119044Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-09-27T08:33:51Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
title Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
spellingShingle Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
Mereiter, S
Gastric cancer
N-glycome
O-glycome
Sialoproteome
Sialyltransferase
title_short Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
title_full Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
title_fullStr Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
title_full_unstemmed Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
title_sort Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4
author Mereiter, S
author_facet Mereiter, S
Magalhães, A
Adamczyk, B
Jin, C
Almeida, A
Drici, L
Ibáñez-Vea, M
Larsen, M
Kolarich, D
Karlsson, N
Reis, CA
author_role author
author2 Magalhães, A
Adamczyk, B
Jin, C
Almeida, A
Drici, L
Ibáñez-Vea, M
Larsen, M
Kolarich, D
Karlsson, N
Reis, CA
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Mereiter, S
Magalhães, A
Adamczyk, B
Jin, C
Almeida, A
Drici, L
Ibáñez-Vea, M
Larsen, M
Kolarich, D
Karlsson, N
Reis, CA
dc.subject.por.fl_str_mv Gastric cancer
N-glycome
O-glycome
Sialoproteome
Sialyltransferase
topic Gastric cancer
N-glycome
O-glycome
Sialoproteome
Sialyltransferase
description Gastric carcinoma MKN45 cells stably transfected with the full-length ST3GAL4 gene were characterised by glycomic and sialoproteomic analysis. Complementary strategies were applied to assess the glycomic alterations induced by ST3GAL4 overexpression. The N- and O-glycome data were generated in two parallel structural analyzes, based on PGC-ESI-MS/MS. Data on glycan structure identification and relative abundance in ST3GAL4 overexpressing cells and respective mock control are presented. The sialoproteomic analysis based on titanium-dioxide enrichment of sialopeptides with subsequent LC-MS/MS identification was performed. This analysis identified 47 proteins with significantly increased sialylation. The data in this article is associated with the research article published in Biochim Biophys Acta "Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer" [1].
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/119044
url https://hdl.handle.net/10216/119044
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2352-3409
10.1016/j.dib.2016.03.022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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