Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation

Detalhes bibliográficos
Autor(a) principal: Nunes-Ferreira, Afonso
Data de Publicação: 2018
Outros Autores: R. Agostinho, João, Cortez-Dias, Nuno, Silva, G. Lima da, Francisco, Ana Rita, Guimarães, T., Gonçalves, I. Santos, Aguiar-Ricardo, Inês, Rigueira, Joana, Bernardes, A., Carpinteiro, L., Pinto, Fausto J, Sousa, Joana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/40045
Resumo: © The European Society of Cardiology 2018. All rights reserved.
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spelling Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation© The European Society of Cardiology 2018. All rights reserved.Introduction: Adenosine test has been increasingly used to confirm pulmonary vein isolation (PVI) in patients undergoing ablation of atrial fibrillation (AF). However, its impact on the success of ablation remains unknown. Purposes: To evaluate the results of the adenosine triphosphate (ATP) test in patients undergoing PVI and assess the success of ablation related to the use of this test (adenosine-guided PVI versus conventional PVI). Methods: Single-center prospective study of consecutive patients undergoing first AF ablation procedure, started at January 2013. After ablation, the persistence of PVI was tested with adenosine triphosphate administration (15–30mg by intravenous route). When adenosine triphosphate-induced pulmonary vein conduction (termed as reconduction) was observed, additional energy applications of radiofrequency were applied to obtain persistent isolation on retesting. Cardiac event recorder was performed at 7 days, 3, 6 and 12 months after ablation and annually from the 2nd year. The adenosine triphosphate-induced reconduction rate was evaluated depending on the pulmonary vein involved. The impact of adenosine test implementation in the success of the ablation at 365 days (recurrence of AF or supraventricular tachycardia) was determined by analysis of overall survival using Kaplan-Meier method. Results: Adenosine test was performed on 151 patients, with reconduction detected on at least one of the pulmonary veins in 11 patients (33.8%) and in 17.6% of the 641 pulmonary veins evaluated, with no statistically significant difference between the different veins. The overall success rate of AF ablation at 365 days was 72% and did not differ significantly between adenosine-guided PVI versus conventional PVI (74.3% versus 70.8%, P = NS), although the duration of follow-up had been shorter in the first group (median of 13.0 vs. 38.3 months; p<0.001). Conclusion: The adenosine-induced reconduction occurs in about one third of the patients. However, the additional adenosine-guided energy applications do not seem to increase the overall success of ablation. We found no significant reduction in the 1 year incidence of recurrent atrial tachyarrhythmias by ATP-guided PVI compared with conventional PVI.Oxford University PressRepositório da Universidade de LisboaNunes-Ferreira, AfonsoR. Agostinho, JoãoCortez-Dias, NunoSilva, G. Lima daFrancisco, Ana RitaGuimarães, T.Gonçalves, I. SantosAguiar-Ricardo, InêsRigueira, JoanaBernardes, A.Carpinteiro, L.Pinto, Fausto JSousa, Joana2019-11-04T16:22:23Z20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/40045engEuropean Heart Journal, Volume 39, Issue suppl_1, August 2018, ehy563.P482910.1093/eurheartj/ehy563.P4829info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:39:06Zoai:repositorio.ul.pt:10451/40045Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:53:46.350353Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
title Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
spellingShingle Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
Nunes-Ferreira, Afonso
title_short Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
title_full Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
title_fullStr Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
title_full_unstemmed Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
title_sort Atrial fibrillation ablation : the added value of adenosine test in confirming pulmonary vein isolation
author Nunes-Ferreira, Afonso
author_facet Nunes-Ferreira, Afonso
R. Agostinho, João
Cortez-Dias, Nuno
Silva, G. Lima da
Francisco, Ana Rita
Guimarães, T.
Gonçalves, I. Santos
Aguiar-Ricardo, Inês
Rigueira, Joana
Bernardes, A.
Carpinteiro, L.
Pinto, Fausto J
Sousa, Joana
author_role author
author2 R. Agostinho, João
Cortez-Dias, Nuno
Silva, G. Lima da
Francisco, Ana Rita
Guimarães, T.
Gonçalves, I. Santos
Aguiar-Ricardo, Inês
Rigueira, Joana
Bernardes, A.
Carpinteiro, L.
Pinto, Fausto J
Sousa, Joana
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Nunes-Ferreira, Afonso
R. Agostinho, João
Cortez-Dias, Nuno
Silva, G. Lima da
Francisco, Ana Rita
Guimarães, T.
Gonçalves, I. Santos
Aguiar-Ricardo, Inês
Rigueira, Joana
Bernardes, A.
Carpinteiro, L.
Pinto, Fausto J
Sousa, Joana
description © The European Society of Cardiology 2018. All rights reserved.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01T00:00:00Z
2019-11-04T16:22:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/40045
url http://hdl.handle.net/10451/40045
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv European Heart Journal, Volume 39, Issue suppl_1, August 2018, ehy563.P4829
10.1093/eurheartj/ehy563.P4829
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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