DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft

Detalhes bibliográficos
Autor(a) principal: Moura-Coelho, Nuno
Data de Publicação: 2022
Outros Autores: Arrondo, Elena, Papa-Vettorazzi, Mario Renato, Cunha, João Paulo, Güell, José Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/142690
Resumo: Funding Information: No funding or grant support. Publisher Copyright: © 2022
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spelling DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graftA case report and review of the literatureDescemet membrane endothelial keratoplastyDMEKEndothelial keratoplastyInterface fluid syndromeLaser in situ keratomileusisLASIKOphthalmologyFunding Information: No funding or grant support. Publisher Copyright: © 2022Purpose: To report a case of Descemet membrane endothelial keratoplasty (DMEK) for the management of post-laser in situ keratomileusis (LASIK) interface fluid syndrome (IFS) secondary to failed Descemet stripping automated endothelial keratoplasty (DSAEK) graft, and to provide a literature review on endothelial keratoplasty (EK) for this indication. Observations: A 52-year-old patient presented with LASIK interface fluid accumulation and a non-functioning primary DSAEK graft. Past ophthalmic history was relevant for: (1) phakic intraocular lens (PIOL) implantation with later refinement by LASIK; (2) combined PIOL explantation and refractive lens exchange due to accelerated endothelial cell loss (ECL); (3) primary DSAEK due to corneal decompensation. A secondary EK graft (DMEK) was performed, and the patient was prospectively followed for 6 months (M6). DMEK surgery was uneventful, without postoperative graft detachment. Corneal clearing and resolution of interface fluid accumulation occurred during the first postoperative month. Best-corrected visual acuity (BCVA) improved from 20/800 Snellen to 20/25 Snellen at 3-month follow-up, remaining stable at M6. Due to a persistent rise in intraocular pressure (IOP), the patient underwent uneventful non-penetrating deep sclerectomy 2 months after DMEK, with controlled IOP and without accelerated ECL. Conclusions and Importance: DMEK is feasible, effective, and safe in the management of IFS in cases where corneal endothelial failure plays a major role, even in complex eyes with previous EK grafts. Aggressive postoperative IOP control is warranted to decrease the risk of interface fluid recurrence and damage to the optic nerve. Studies with larger patient numbers are encouraged to ascertain the role of EK for this indication.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNMoura-Coelho, NunoArrondo, ElenaPapa-Vettorazzi, Mario RenatoCunha, João PauloGüell, José Luis2022-07-29T22:24:40Z2022-092022-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/142690eng2451-9936PURE: 45661512https://doi.org/10.1016/j.ajoc.2022.101656info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:20:33Zoai:run.unl.pt:10362/142690Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:50:28.549361Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
A case report and review of the literature
title DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
spellingShingle DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
Moura-Coelho, Nuno
Descemet membrane endothelial keratoplasty
DMEK
Endothelial keratoplasty
Interface fluid syndrome
Laser in situ keratomileusis
LASIK
Ophthalmology
title_short DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
title_full DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
title_fullStr DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
title_full_unstemmed DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
title_sort DMEK for the treatment of interface fluid syndrome secondary to failed DSAEK graft
author Moura-Coelho, Nuno
author_facet Moura-Coelho, Nuno
Arrondo, Elena
Papa-Vettorazzi, Mario Renato
Cunha, João Paulo
Güell, José Luis
author_role author
author2 Arrondo, Elena
Papa-Vettorazzi, Mario Renato
Cunha, João Paulo
Güell, José Luis
author2_role author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Moura-Coelho, Nuno
Arrondo, Elena
Papa-Vettorazzi, Mario Renato
Cunha, João Paulo
Güell, José Luis
dc.subject.por.fl_str_mv Descemet membrane endothelial keratoplasty
DMEK
Endothelial keratoplasty
Interface fluid syndrome
Laser in situ keratomileusis
LASIK
Ophthalmology
topic Descemet membrane endothelial keratoplasty
DMEK
Endothelial keratoplasty
Interface fluid syndrome
Laser in situ keratomileusis
LASIK
Ophthalmology
description Funding Information: No funding or grant support. Publisher Copyright: © 2022
publishDate 2022
dc.date.none.fl_str_mv 2022-07-29T22:24:40Z
2022-09
2022-09-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/142690
url http://hdl.handle.net/10362/142690
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2451-9936
PURE: 45661512
https://doi.org/10.1016/j.ajoc.2022.101656
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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