Mitochondrial DNA in human identification: a review

Detalhes bibliográficos
Autor(a) principal: Amorim, António
Data de Publicação: 2019
Outros Autores: Fernandes, Teresa, Taveira, Nuno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/36762
https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314
https://doi.org/10.7717/peerj.7314
Resumo: Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics.
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spelling Mitochondrial DNA in human identification: a reviewMitochondrial DNAHuman identificationForensic biologyLegal medicineDNA MitocondrialIdentificação HumanaGenética ForenseMitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics.info:eu-repo/semantics/publishedVersionPeerJ Inc.2021-06-14T09:59:55Z2021-06-142019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/36762https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314http://hdl.handle.net/10400.26/36762https://doi.org/10.7717/peerj.7314eng2167-8359https://peerj.com/articles/7314/http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAmorim, AntónioFernandes, TeresaTaveira, Nunoreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:21:42Zoai:comum.rcaap.pt:10400.26/36762Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:40.731689Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Mitochondrial DNA in human identification: a review
title Mitochondrial DNA in human identification: a review
spellingShingle Mitochondrial DNA in human identification: a review
Amorim, António
Mitochondrial DNA
Human identification
Forensic biology
Legal medicine
DNA Mitocondrial
Identificação Humana
Genética Forense
title_short Mitochondrial DNA in human identification: a review
title_full Mitochondrial DNA in human identification: a review
title_fullStr Mitochondrial DNA in human identification: a review
title_full_unstemmed Mitochondrial DNA in human identification: a review
title_sort Mitochondrial DNA in human identification: a review
author Amorim, António
author_facet Amorim, António
Fernandes, Teresa
Taveira, Nuno
author_role author
author2 Fernandes, Teresa
Taveira, Nuno
author2_role author
author
dc.contributor.author.fl_str_mv Amorim, António
Fernandes, Teresa
Taveira, Nuno
dc.subject.por.fl_str_mv Mitochondrial DNA
Human identification
Forensic biology
Legal medicine
DNA Mitocondrial
Identificação Humana
Genética Forense
topic Mitochondrial DNA
Human identification
Forensic biology
Legal medicine
DNA Mitocondrial
Identificação Humana
Genética Forense
description Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01T00:00:00Z
2021-06-14T09:59:55Z
2021-06-14
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/36762
https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314
http://hdl.handle.net/10400.26/36762
https://doi.org/10.7717/peerj.7314
url http://hdl.handle.net/10400.26/36762
https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314
https://doi.org/10.7717/peerj.7314
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2167-8359
https://peerj.com/articles/7314/
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv PeerJ Inc.
publisher.none.fl_str_mv PeerJ Inc.
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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