Mitochondrial DNA in human identification: a review
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/36762 https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314 https://doi.org/10.7717/peerj.7314 |
Resumo: | Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics. |
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Mitochondrial DNA in human identification: a reviewMitochondrial DNAHuman identificationForensic biologyLegal medicineDNA MitocondrialIdentificação HumanaGenética ForenseMitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics.info:eu-repo/semantics/publishedVersionPeerJ Inc.2021-06-14T09:59:55Z2021-06-142019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/36762https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314http://hdl.handle.net/10400.26/36762https://doi.org/10.7717/peerj.7314eng2167-8359https://peerj.com/articles/7314/http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAmorim, AntónioFernandes, TeresaTaveira, Nunoreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:21:42Zoai:comum.rcaap.pt:10400.26/36762Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:40.731689Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mitochondrial DNA in human identification: a review |
title |
Mitochondrial DNA in human identification: a review |
spellingShingle |
Mitochondrial DNA in human identification: a review Amorim, António Mitochondrial DNA Human identification Forensic biology Legal medicine DNA Mitocondrial Identificação Humana Genética Forense |
title_short |
Mitochondrial DNA in human identification: a review |
title_full |
Mitochondrial DNA in human identification: a review |
title_fullStr |
Mitochondrial DNA in human identification: a review |
title_full_unstemmed |
Mitochondrial DNA in human identification: a review |
title_sort |
Mitochondrial DNA in human identification: a review |
author |
Amorim, António |
author_facet |
Amorim, António Fernandes, Teresa Taveira, Nuno |
author_role |
author |
author2 |
Fernandes, Teresa Taveira, Nuno |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Amorim, António Fernandes, Teresa Taveira, Nuno |
dc.subject.por.fl_str_mv |
Mitochondrial DNA Human identification Forensic biology Legal medicine DNA Mitocondrial Identificação Humana Genética Forense |
topic |
Mitochondrial DNA Human identification Forensic biology Legal medicine DNA Mitocondrial Identificação Humana Genética Forense |
description |
Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01T00:00:00Z 2021-06-14T09:59:55Z 2021-06-14 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/36762 https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314 http://hdl.handle.net/10400.26/36762 https://doi.org/10.7717/peerj.7314 |
url |
http://hdl.handle.net/10400.26/36762 https://doi.org/Amorim, A., Fernandes, T., & Taveira, N. (2019). Mitochondrial DNA in human identification: a review. PeerJ, 7, e7314. https://doi.org/10.7717/peerj.7314 https://doi.org/10.7717/peerj.7314 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2167-8359 https://peerj.com/articles/7314/ |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
PeerJ Inc. |
publisher.none.fl_str_mv |
PeerJ Inc. |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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