Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review

Detalhes bibliográficos
Autor(a) principal: Cabo, João
Data de Publicação: 2020
Outros Autores: Martins, Luís, Tavares e Castro, Ana, Maltez, Fernando
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706
Resumo: Due to unfavorable conditions for survival and multiplication of Mycobacterium tuberculosis, muscle and soft tissue involvement is probably the rarest form of presentation of musculoskeletal tuberculosis, particularly without a clinically or radiologically apparent primary focus. As in other extrapulmonary forms of tuberculosis, its relative incidence is higher among immunocompromised patients. A progressive swelling is the most common complaint at presentation, which is otherwise mild and nonspecific. We present a case of multifocal (seven) subcutaneous and muscular tuberculous abscesses in a 29-year-old Indian patient who had no apparent underlying risk factors, nor any other organ involvement. Provisional diagnosis was initially made upon Mycobacterium tuberculosis complex nucleic acid detection in an aspirate of one of the collections and later confirmed by a positive culture on Lowenstein-Jensen medium. Two abscesses required aspiration and two others drained spontaneously. The patient responded well to nine months of anti-tuberculous therapy. An extensive review of the literature was made.
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spelling Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature ReviewTuberculose Muscular e Subcutânea Multifocal num Jovem Imunocompetente: Descrição de um Caso-Clínico e Revisão da LiteraturaImmunocompetenceMuscular DiseasesMycobacterium tuberculosisPyomyositisTuberculosisDoenças MuscularesImunocompetênciaMycobacterium tuberculosisPiomiositeTuberculoseDue to unfavorable conditions for survival and multiplication of Mycobacterium tuberculosis, muscle and soft tissue involvement is probably the rarest form of presentation of musculoskeletal tuberculosis, particularly without a clinically or radiologically apparent primary focus. As in other extrapulmonary forms of tuberculosis, its relative incidence is higher among immunocompromised patients. A progressive swelling is the most common complaint at presentation, which is otherwise mild and nonspecific. We present a case of multifocal (seven) subcutaneous and muscular tuberculous abscesses in a 29-year-old Indian patient who had no apparent underlying risk factors, nor any other organ involvement. Provisional diagnosis was initially made upon Mycobacterium tuberculosis complex nucleic acid detection in an aspirate of one of the collections and later confirmed by a positive culture on Lowenstein-Jensen medium. Two abscesses required aspiration and two others drained spontaneously. The patient responded well to nine months of anti-tuberculous therapy. An extensive review of the literature was made.Devido à presença de condições adversas para a sobrevivência e multiplicação do Mycobacterium tuberculosis, o envolvimento dos músculos e tecidos moles representa a forma de apresentação mais rara da tuberculose músculo-esquelética, sobretudo na ausência de um foco primário clínica ou radiologicamente evidente. Tal como nas outras formas de tuberculose extra-pulmonar, a sua incidência relativa é mais elevada em indivíduos imunodeprimidos. A apresentação clínica, habitualmente uma tumefação de crescimento progressivo, é insidiosa e inespecífica. Os autores descrevem um caso de múltiplos (sete) abcessos tuberculosos subcutâneos e musculares num jovem indiano de 29 anos sem qualquer fator de risco subjacente nem envolvimento de outros órgãos. A deteção de ácidos núcleicos de Mycobacterium tuberculosis complex no conteúdo de uma das coleções colhido por aspiração permitiu um diagnóstico provisório, confirmado posteriormente por isolamento em cultura em meio de Lowenstein-Jensen. Dois dos abcessos necessitaram de drenagem por aspiração, enquanto outros dois drenaram de forma espontânea. O doente apresentou uma resposta favorável com nove meses de terapêutica anti-bacilar. Os autores completam o trabalho com uma extensa revisão sobre o tema.Ordem dos Médicos2020-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706oai:ojs.www.actamedicaportuguesa.com:article/10706Acta Médica Portuguesa; Vol. 33 No. 7-8 (2020): July-August; 516-520Acta Médica Portuguesa; Vol. 33 N.º 7-8 (2020): Julho-Agosto; 516-5201646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/5786https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10279https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10300https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10301https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10302https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10303https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10304https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10305https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10306https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10556Direitos de Autor (c) 2019 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessCabo, JoãoMartins, LuísTavares e Castro, AnaMaltez, Fernando2022-12-20T11:06:04Zoai:ojs.www.actamedicaportuguesa.com:article/10706Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:55.937080Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
Tuberculose Muscular e Subcutânea Multifocal num Jovem Imunocompetente: Descrição de um Caso-Clínico e Revisão da Literatura
title Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
spellingShingle Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
Cabo, João
Immunocompetence
Muscular Diseases
Mycobacterium tuberculosis
Pyomyositis
Tuberculosis
Doenças Musculares
Imunocompetência
Mycobacterium tuberculosis
Piomiosite
Tuberculose
title_short Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
title_full Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
title_fullStr Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
title_full_unstemmed Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
title_sort Multifocal Subcutaneous and Muscular Tuberculosis in a Young Immunocompetent Man: A Case Report and Literature Review
author Cabo, João
author_facet Cabo, João
Martins, Luís
Tavares e Castro, Ana
Maltez, Fernando
author_role author
author2 Martins, Luís
Tavares e Castro, Ana
Maltez, Fernando
author2_role author
author
author
dc.contributor.author.fl_str_mv Cabo, João
Martins, Luís
Tavares e Castro, Ana
Maltez, Fernando
dc.subject.por.fl_str_mv Immunocompetence
Muscular Diseases
Mycobacterium tuberculosis
Pyomyositis
Tuberculosis
Doenças Musculares
Imunocompetência
Mycobacterium tuberculosis
Piomiosite
Tuberculose
topic Immunocompetence
Muscular Diseases
Mycobacterium tuberculosis
Pyomyositis
Tuberculosis
Doenças Musculares
Imunocompetência
Mycobacterium tuberculosis
Piomiosite
Tuberculose
description Due to unfavorable conditions for survival and multiplication of Mycobacterium tuberculosis, muscle and soft tissue involvement is probably the rarest form of presentation of musculoskeletal tuberculosis, particularly without a clinically or radiologically apparent primary focus. As in other extrapulmonary forms of tuberculosis, its relative incidence is higher among immunocompromised patients. A progressive swelling is the most common complaint at presentation, which is otherwise mild and nonspecific. We present a case of multifocal (seven) subcutaneous and muscular tuberculous abscesses in a 29-year-old Indian patient who had no apparent underlying risk factors, nor any other organ involvement. Provisional diagnosis was initially made upon Mycobacterium tuberculosis complex nucleic acid detection in an aspirate of one of the collections and later confirmed by a positive culture on Lowenstein-Jensen medium. Two abscesses required aspiration and two others drained spontaneously. The patient responded well to nine months of anti-tuberculous therapy. An extensive review of the literature was made.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-01
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dc.language.iso.fl_str_mv eng
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10279
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10300
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10301
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10302
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10303
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10305
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10706/10306
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dc.rights.driver.fl_str_mv Direitos de Autor (c) 2019 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2019 Acta Médica Portuguesa
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application/pdf
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image/jpeg
image/jpeg
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 33 No. 7-8 (2020): July-August; 516-520
Acta Médica Portuguesa; Vol. 33 N.º 7-8 (2020): Julho-Agosto; 516-520
1646-0758
0870-399X
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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