Gravidez após transplante renal: interação entre a gestação e o enxerto
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003 |
Resumo: | Overview and aims: Kidney transplantation has brought a new hope to women with end stage renal disease (ESRD) who wish to become pregnant, as it can improve the reproductive function and restore fertility. A successful pregnancy after kidney transplant is possible, at expenses of high rates of maternal and fetal morbidity. The objective of the study is to investigate the impact of renal transplantation in obstetric and neonatal outcomes as well as the effect of pregnancy itself in the graft. Study design: Retrospective study and descriptive analysis Methods and population: Retrospective study of nine pregnancies in eight renal transplant recipients between 1995 and 2015 in Centro Hospitalar São João. We evaluated the pre-pregnancy and post-delivery renal function, outcomes of gestation, as well as maternal and fetal complications. Results: The average time between transplant and pregnancy was 51.1 ± 25.3 months. The most common complications were urinary tract infections (7 cases), preterm delivery (6 cases), fetal growth restriction (3 cases), and pre-eclampsia (2 cases). One case of intrauterine fetal death was recorded. The cesarean section rate was 66.7%. There were two cases of graft dysfunction, which resolved in the postpartum period, without rejection or graft loss. In one patient, graft dysfunction recurred five months post-delivery due to native kidney disease relapse. Currently, one year after delivery, her creatinine plasmatic level is 2.2 mg/dL. Conclusions: This study suggests that successful pregnancy is possible in renal transplant recipients. Neverthless, these pregnancies should be considered at high risk and we must be alert to the complications that may occur |
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Gravidez após transplante renal: interação entre a gestação e o enxertoRenal transplantPregnancyOverview and aims: Kidney transplantation has brought a new hope to women with end stage renal disease (ESRD) who wish to become pregnant, as it can improve the reproductive function and restore fertility. A successful pregnancy after kidney transplant is possible, at expenses of high rates of maternal and fetal morbidity. The objective of the study is to investigate the impact of renal transplantation in obstetric and neonatal outcomes as well as the effect of pregnancy itself in the graft. Study design: Retrospective study and descriptive analysis Methods and population: Retrospective study of nine pregnancies in eight renal transplant recipients between 1995 and 2015 in Centro Hospitalar São João. We evaluated the pre-pregnancy and post-delivery renal function, outcomes of gestation, as well as maternal and fetal complications. Results: The average time between transplant and pregnancy was 51.1 ± 25.3 months. The most common complications were urinary tract infections (7 cases), preterm delivery (6 cases), fetal growth restriction (3 cases), and pre-eclampsia (2 cases). One case of intrauterine fetal death was recorded. The cesarean section rate was 66.7%. There were two cases of graft dysfunction, which resolved in the postpartum period, without rejection or graft loss. In one patient, graft dysfunction recurred five months post-delivery due to native kidney disease relapse. Currently, one year after delivery, her creatinine plasmatic level is 2.2 mg/dL. Conclusions: This study suggests that successful pregnancy is possible in renal transplant recipients. Neverthless, these pregnancies should be considered at high risk and we must be alert to the complications that may occurEuromédice, Edições Médicas Lda.2017-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003Acta Obstétrica e Ginecológica Portuguesa v.11 n.3 2017reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003Ferreira,CátiaFerreira,HugoMachado,Ana PaulaSantos,JoanaMontenegro,Nunoinfo:eu-repo/semantics/openAccess2024-02-06T17:21:38Zoai:scielo:S1646-58302017000300003Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:28:36.290704Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
title |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
spellingShingle |
Gravidez após transplante renal: interação entre a gestação e o enxerto Ferreira,Cátia Renal transplant Pregnancy |
title_short |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
title_full |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
title_fullStr |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
title_full_unstemmed |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
title_sort |
Gravidez após transplante renal: interação entre a gestação e o enxerto |
author |
Ferreira,Cátia |
author_facet |
Ferreira,Cátia Ferreira,Hugo Machado,Ana Paula Santos,Joana Montenegro,Nuno |
author_role |
author |
author2 |
Ferreira,Hugo Machado,Ana Paula Santos,Joana Montenegro,Nuno |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferreira,Cátia Ferreira,Hugo Machado,Ana Paula Santos,Joana Montenegro,Nuno |
dc.subject.por.fl_str_mv |
Renal transplant Pregnancy |
topic |
Renal transplant Pregnancy |
description |
Overview and aims: Kidney transplantation has brought a new hope to women with end stage renal disease (ESRD) who wish to become pregnant, as it can improve the reproductive function and restore fertility. A successful pregnancy after kidney transplant is possible, at expenses of high rates of maternal and fetal morbidity. The objective of the study is to investigate the impact of renal transplantation in obstetric and neonatal outcomes as well as the effect of pregnancy itself in the graft. Study design: Retrospective study and descriptive analysis Methods and population: Retrospective study of nine pregnancies in eight renal transplant recipients between 1995 and 2015 in Centro Hospitalar São João. We evaluated the pre-pregnancy and post-delivery renal function, outcomes of gestation, as well as maternal and fetal complications. Results: The average time between transplant and pregnancy was 51.1 ± 25.3 months. The most common complications were urinary tract infections (7 cases), preterm delivery (6 cases), fetal growth restriction (3 cases), and pre-eclampsia (2 cases). One case of intrauterine fetal death was recorded. The cesarean section rate was 66.7%. There were two cases of graft dysfunction, which resolved in the postpartum period, without rejection or graft loss. In one patient, graft dysfunction recurred five months post-delivery due to native kidney disease relapse. Currently, one year after delivery, her creatinine plasmatic level is 2.2 mg/dL. Conclusions: This study suggests that successful pregnancy is possible in renal transplant recipients. Neverthless, these pregnancies should be considered at high risk and we must be alert to the complications that may occur |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000300003 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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text/html |
dc.publisher.none.fl_str_mv |
Euromédice, Edições Médicas Lda. |
publisher.none.fl_str_mv |
Euromédice, Edições Médicas Lda. |
dc.source.none.fl_str_mv |
Acta Obstétrica e Ginecológica Portuguesa v.11 n.3 2017 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1817550068081754112 |