Study of dosimetry techniques applied to electron beams with high dose rate

Detalhes bibliográficos
Autor(a) principal: Sousa, Edgar Alexandre Piazentim Ferreira da Mota e
Data de Publicação: 2023
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/62218
Resumo: Tese de mestrado, Engenharia Física, 2023, Universidade de Lisboa, Faculdade de Ciências
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spelling Study of dosimetry techniques applied to electron beams with high dose rateElectrõesDosimetriaTSEIElektaTOPASTeses de mestrado - 2023Departamento de FísicaTese de mestrado, Engenharia Física, 2023, Universidade de Lisboa, Faculdade de CiênciasElectron beams of 4-20 MeV are used for Total Skin Electron Irradiation (TSEI) of T-cell lymphomas like the mycosis fungoides type. High dose rate electron (HDRE) beams show effectiveness in achieving local control rates close to 100% and low rates of acute and late toxicity. An Elekta Infinity Agility machine was modeled without manufacturer information and the resulting 6 MeV (TSEI compatible energy) beam was compared with reference experimental beam. The dosimetric study was conducted using Advanced Markus® Type 34045 plane-parallel ionization chamber (IC) and GafChromicTM EBT-XD films. Both water (MP3) and solid water (RW3) were used, and beam evaluation involved reference 10x10 cm2 fields and 100 cm SSD as well as open fields and 240 cm SSD TSEI compatible. Functional performance testing was done for evaluation of beam constancy in HDRE operating mode. Results show a 0.983 Gy per 100 MU in reference conditions and a 9.115 times higher dose using HDRE mode. Gamma analysis passing of 100 % (2 mm DTA / 2 % DD) was obtained, for comparison between MP3 and RW3 HDRE beams in an open field configuration and for an SSD of 100 cm. The working range was within the effective range of EBTXD films. On a 240 cm spaced perpendicular plane, relative dose was verified as symmetrical within a 15 % tolerance. In an anthropomorphic phantom, dose was analyzed using the dual-field Stanford technique and dmax shift was seen to occur, discarding interface artifacts, from 1.40 ± 0.05 cm (SSDref) to 0.7 ± 0.2 cm. From TOPAS MC simulation, gamma analysis has shown that the model agrees completely with reference beam. Limited agreement was seen using SSD of 240 cm. MC model mimics the studied linac using reference conditions and SSD of 240 cm is adequate for TSEI implementation. More studies for confirmation of results and others focusing on non-reference conditions are needed.Peralta, Luís Filipe dos Santos Garcia, 1961-Repositório da Universidade de LisboaSousa, Edgar Alexandre Piazentim Ferreira da Mota e2024-01-25T09:29:14Z202320232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10451/62218enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-29T01:21:13Zoai:repositorio.ul.pt:10451/62218Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:58:39.237909Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Study of dosimetry techniques applied to electron beams with high dose rate
title Study of dosimetry techniques applied to electron beams with high dose rate
spellingShingle Study of dosimetry techniques applied to electron beams with high dose rate
Sousa, Edgar Alexandre Piazentim Ferreira da Mota e
Electrões
Dosimetria
TSEI
Elekta
TOPAS
Teses de mestrado - 2023
Departamento de Física
title_short Study of dosimetry techniques applied to electron beams with high dose rate
title_full Study of dosimetry techniques applied to electron beams with high dose rate
title_fullStr Study of dosimetry techniques applied to electron beams with high dose rate
title_full_unstemmed Study of dosimetry techniques applied to electron beams with high dose rate
title_sort Study of dosimetry techniques applied to electron beams with high dose rate
author Sousa, Edgar Alexandre Piazentim Ferreira da Mota e
author_facet Sousa, Edgar Alexandre Piazentim Ferreira da Mota e
author_role author
dc.contributor.none.fl_str_mv Peralta, Luís Filipe dos Santos Garcia, 1961-
Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Sousa, Edgar Alexandre Piazentim Ferreira da Mota e
dc.subject.por.fl_str_mv Electrões
Dosimetria
TSEI
Elekta
TOPAS
Teses de mestrado - 2023
Departamento de Física
topic Electrões
Dosimetria
TSEI
Elekta
TOPAS
Teses de mestrado - 2023
Departamento de Física
description Tese de mestrado, Engenharia Física, 2023, Universidade de Lisboa, Faculdade de Ciências
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023-01-01T00:00:00Z
2024-01-25T09:29:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/62218
url http://hdl.handle.net/10451/62218
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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