Effect of pupil size on corneal aberrations before and after standard, custom LASIK and corneal refractive therapy

• Autor(a) principal: Queirós, A.
• Data de Publicação: 2010
• Outros Autores: Villa-Collar, César, González-Méijome, José Manuel, Jorge, Jorge, Ramón Gutiérrez, Angel
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/1822/12918
• topic: LASIK; Corneal aberrations; Corneal refractive therapy; Pupil diameter; Science & Technology

PURPOSE: To evaluate the effect of changing the pupil size on the corneal first surface higher order aberrations induced by different refractive treatments (standard LASIK; custom LASIK and corneal refractive therapy). DESIGN: Observational study. METHODS: SETTING: Clínica Oftalmológica NovoVisión, Madrid, Spain. PATIENTS: Eighty-one right eyes with a mean age of 29.94±7.5 years, of which 50 were female (61.7%), were retrospectively analyzed. Corneal videokeratographic data were used to obtain corneal first surface higher order aberrations (HOA) for aperture diameters from 3 to 8 mm using the Vol-CT software. Total Root Mean Square (RMS) and RMS for 3rd to 6th-order Zernike polynomials as well as spherical-like, coma-like, secondary-astigmatism and spherical+coma-like were calculated. RESULTS: We verified an increase of the HOA Total RMS after treatments of 0.014±0.025µm, 0.019±0.027µm 0.018±0.031µm for standard LASIK, custom LASIK and corneal refractive therapy, respectively for 3mm pupil diameter. For the 8mm aperture diameter changes in Total RMS increased by a factor of 50x compared with the variation for the 3mm diameter up to 0.744±0.731µm, 0.493±0.794µm, 0.973±1.055µm for standard LASIK, custom LASIK and corneal refractive therapy, respectively. CONCLUSIONS: The three techniques increase the wavefront aberrations of the cornea and change the relative contribution of coma-like and spherical-like aberrations. For a large aperture (>5mm), corneal refractive therapy induces more spherical-like aberrations than standard LASIK and this more than custom LASIK. However, no differences clinically or statistically significant did exist for narrower apertures. Standard LASIK and custom LASIK did not displayed statistically significant differences regarding to HOA.