Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.48750/acv.552 |
Resumo: | INTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is scarce and conflicting results exist regarding cardiovascular, cerebrovascular and limb outcomes. METHODS: We performed a thorough electronic search of the literature using PubMed and Embase databases to understand the relationship between statin effect and cardiovascular, limb outcomes and cerebrovascular outcomes. A narrative review was constructed, based on the obtained literature. RESULTS: Although the use of statins in hemodialysis patients may provide cardiovascular benefits, the optimal dosage and safety profile of these medications in this population remain uncertain. A carefully evaluation of the risks and benefits of statins should be made based on each patient's specific requirements and circumstances. CONCLUSION: The role of statins for patients with peripheral arterial disease who are on hemodialysis remains unclear. Further analyses should focus on this subgroup of dialysis patients, who are becoming more prevalent on the vascular surgery departments, allowing for an optimized treatment with better patient outcomes. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative reviewStatinHemodialysisperipheral arterial diseasepatient outcomesINTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is scarce and conflicting results exist regarding cardiovascular, cerebrovascular and limb outcomes. METHODS: We performed a thorough electronic search of the literature using PubMed and Embase databases to understand the relationship between statin effect and cardiovascular, limb outcomes and cerebrovascular outcomes. A narrative review was constructed, based on the obtained literature. RESULTS: Although the use of statins in hemodialysis patients may provide cardiovascular benefits, the optimal dosage and safety profile of these medications in this population remain uncertain. A carefully evaluation of the risks and benefits of statins should be made based on each patient's specific requirements and circumstances. CONCLUSION: The role of statins for patients with peripheral arterial disease who are on hemodialysis remains unclear. Further analyses should focus on this subgroup of dialysis patients, who are becoming more prevalent on the vascular surgery departments, allowing for an optimized treatment with better patient outcomes.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2024-03-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.552https://doi.org/10.48750/acv.552Angiologia e Cirurgia Vascular; Vol. 19 No. 4 (2023): December; 218-220Angiologia e Cirurgia Vascular; Vol. 19 N.º 4 (2023): Dezembro; 218-2202183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://acvjournal.com/index.php/acv/article/view/552http://acvjournal.com/index.php/acv/article/view/552/360Copyright (c) 2024 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessNunes, CelsoSousa, JulianaOliveira, VâniaSilva, EduardoBaldaia, LeonorSilva, MiguelOrelhas, LuisFonseca, Manuel2024-03-08T10:30:14Zoai:ojs.acvjournal.com:article/552Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:13:56.911456Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
title |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
spellingShingle |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review Nunes, Celso Statin Hemodialysis peripheral arterial disease patient outcomes |
title_short |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
title_full |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
title_fullStr |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
title_full_unstemmed |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
title_sort |
Effectiveness of statins on haemodialysis patients with concomitant peripheral arterial disease – a narrative review |
author |
Nunes, Celso |
author_facet |
Nunes, Celso Sousa, Juliana Oliveira, Vânia Silva, Eduardo Baldaia, Leonor Silva, Miguel Orelhas, Luis Fonseca, Manuel |
author_role |
author |
author2 |
Sousa, Juliana Oliveira, Vânia Silva, Eduardo Baldaia, Leonor Silva, Miguel Orelhas, Luis Fonseca, Manuel |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Nunes, Celso Sousa, Juliana Oliveira, Vânia Silva, Eduardo Baldaia, Leonor Silva, Miguel Orelhas, Luis Fonseca, Manuel |
dc.subject.por.fl_str_mv |
Statin Hemodialysis peripheral arterial disease patient outcomes |
topic |
Statin Hemodialysis peripheral arterial disease patient outcomes |
description |
INTRODUCTION: The use of statins in hemodialysis patients is a topic of ongoing research and debate. Patients with chronic kidney disease on hemodialysis constitute a large proportion of patients treated in the vascular surgery field. Clinical data of the protective statin effect on this group is scarce and conflicting results exist regarding cardiovascular, cerebrovascular and limb outcomes. METHODS: We performed a thorough electronic search of the literature using PubMed and Embase databases to understand the relationship between statin effect and cardiovascular, limb outcomes and cerebrovascular outcomes. A narrative review was constructed, based on the obtained literature. RESULTS: Although the use of statins in hemodialysis patients may provide cardiovascular benefits, the optimal dosage and safety profile of these medications in this population remain uncertain. A carefully evaluation of the risks and benefits of statins should be made based on each patient's specific requirements and circumstances. CONCLUSION: The role of statins for patients with peripheral arterial disease who are on hemodialysis remains unclear. Further analyses should focus on this subgroup of dialysis patients, who are becoming more prevalent on the vascular surgery departments, allowing for an optimized treatment with better patient outcomes. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-03-03 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.48750/acv.552 https://doi.org/10.48750/acv.552 |
url |
https://doi.org/10.48750/acv.552 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://acvjournal.com/index.php/acv/article/view/552 http://acvjournal.com/index.php/acv/article/view/552/360 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2024 Angiologia e Cirurgia Vascular info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2024 Angiologia e Cirurgia Vascular |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Angiologia e Cirurgia Vascular |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Angiologia e Cirurgia Vascular |
dc.source.none.fl_str_mv |
Angiologia e Cirurgia Vascular; Vol. 19 No. 4 (2023): December; 218-220 Angiologia e Cirurgia Vascular; Vol. 19 N.º 4 (2023): Dezembro; 218-220 2183-0096 1646-706X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799137792767295488 |