Cyclosporin A--a therapeutic alternative in giant-cell arteritis?.
Autor(a) principal: | |
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Data de Publicação: | 1993 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079 |
Resumo: | Cyclosporine A (CyA) is an immune modulator that may treat immune diseases. The authors present two cases of temporal arteritis treated with CyA; the two patients improved very quickly and after the first six or eight weeks of treatment there were no clinical or laboratory signs of inflammation. As to adverse effects there was a moderate increase in serum creatinine and arterial pressure levels which were controlled when the CyA dosage was reduced. In view of the good results achieved in these two patients, the authors concluded that CyA may be an alternative therapy for giant-cell arteritis and that this hypothesis should be further investigated in a larger group of patients. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Cyclosporin A--a therapeutic alternative in giant-cell arteritis?.Ciclosporina A--alternativa terapêutica na arterite de células gigantes?Cyclosporine A (CyA) is an immune modulator that may treat immune diseases. The authors present two cases of temporal arteritis treated with CyA; the two patients improved very quickly and after the first six or eight weeks of treatment there were no clinical or laboratory signs of inflammation. As to adverse effects there was a moderate increase in serum creatinine and arterial pressure levels which were controlled when the CyA dosage was reduced. In view of the good results achieved in these two patients, the authors concluded that CyA may be an alternative therapy for giant-cell arteritis and that this hypothesis should be further investigated in a larger group of patients.Cyclosporine A (CyA) is an immune modulator that may treat immune diseases. The authors present two cases of temporal arteritis treated with CyA; the two patients improved very quickly and after the first six or eight weeks of treatment there were no clinical or laboratory signs of inflammation. As to adverse effects there was a moderate increase in serum creatinine and arterial pressure levels which were controlled when the CyA dosage was reduced. In view of the good results achieved in these two patients, the authors concluded that CyA may be an alternative therapy for giant-cell arteritis and that this hypothesis should be further investigated in a larger group of patients.Ordem dos Médicos1993-05-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079oai:ojs.www.actamedicaportuguesa.com:article/3079Acta Médica Portuguesa; Vol. 6 No. 5 (1993): Maio; 215-8Acta Médica Portuguesa; Vol. 6 N.º 5 (1993): Maio; 215-81646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079/2421Sampaio, JPais, M JLebre, LSousa, AMartins, A PSimões, Jinfo:eu-repo/semantics/openAccess2022-12-20T11:01:36Zoai:ojs.www.actamedicaportuguesa.com:article/3079Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:08.476131Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. Ciclosporina A--alternativa terapêutica na arterite de células gigantes? |
title |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
spellingShingle |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. Sampaio, J |
title_short |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
title_full |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
title_fullStr |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
title_full_unstemmed |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
title_sort |
Cyclosporin A--a therapeutic alternative in giant-cell arteritis?. |
author |
Sampaio, J |
author_facet |
Sampaio, J Pais, M J Lebre, L Sousa, A Martins, A P Simões, J |
author_role |
author |
author2 |
Pais, M J Lebre, L Sousa, A Martins, A P Simões, J |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Sampaio, J Pais, M J Lebre, L Sousa, A Martins, A P Simões, J |
description |
Cyclosporine A (CyA) is an immune modulator that may treat immune diseases. The authors present two cases of temporal arteritis treated with CyA; the two patients improved very quickly and after the first six or eight weeks of treatment there were no clinical or laboratory signs of inflammation. As to adverse effects there was a moderate increase in serum creatinine and arterial pressure levels which were controlled when the CyA dosage was reduced. In view of the good results achieved in these two patients, the authors concluded that CyA may be an alternative therapy for giant-cell arteritis and that this hypothesis should be further investigated in a larger group of patients. |
publishDate |
1993 |
dc.date.none.fl_str_mv |
1993-05-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079 oai:ojs.www.actamedicaportuguesa.com:article/3079 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/3079 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3079/2421 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 6 No. 5 (1993): Maio; 215-8 Acta Médica Portuguesa; Vol. 6 N.º 5 (1993): Maio; 215-8 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799130633551740928 |