Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection

Detalhes bibliográficos
Autor(a) principal: Magalhães, Sara
Data de Publicação: 2016
Outros Autores: Sucena, Élio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/797
Resumo: The deposited article is a post-print version and has peer-review. There are no funders and sponsors indicated explicitly in the document. There is no public supplementary material available. This publication hasn't any creative commons license associated.
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spelling Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infectionadaptationgenomics/proteomicshost-parasite interactionsinsectsquantitative geneticsThe deposited article is a post-print version and has peer-review. There are no funders and sponsors indicated explicitly in the document. There is no public supplementary material available. This publication hasn't any creative commons license associated.One of the major challenges in evolutionary biology is to unravel the genetic basis of adaptation. This issue has been gaining momentum in recent years with the accelerated development of novel genetic and genomic techniques and resources. In this issue of Molecular Ecology, Cogni et al. (2016) address the genetic basis of resistance to two viruses in Drosophila melanogaster using a panel of recombinant inbred lines with unprecedented resolution allowing detection of rare alleles and/or alleles of small effect. The study confirms the role of previously identified genes of major effect and adds novel regions with minor effect to the genetic basis of Drosophila resistance to the Drosophila C virus or the sigma virus. Additional analyses reveal the absence of cross-resistance and of epistasis between the various genomic regions. This detailed information on the genetic architecture of host resistance constitutes an important step towards the understanding of both the physiology of antiviral immunity and the evolution of host-parasite interactions.There are no funders and sponsors indicated explicitly in this uploaded article version.WileyARCAMagalhães, SaraSucena, Élio2017-11-02T17:47:57Z2016-10-072016-10-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/797engMagalhães, S. and Sucena, É. (2016), Genetics of host–parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection. Mol Ecol, 25: 4981–4983. doi:10.1111/mec.1383410.1111/mec.13834info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:35:12Zoai:arca.igc.gulbenkian.pt:10400.7/797Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:12:01.314195Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
title Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
spellingShingle Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
Magalhães, Sara
adaptation
genomics/proteomics
host-parasite interactions
insects
quantitative genetics
title_short Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
title_full Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
title_fullStr Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
title_full_unstemmed Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
title_sort Genetics of host-parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection
author Magalhães, Sara
author_facet Magalhães, Sara
Sucena, Élio
author_role author
author2 Sucena, Élio
author2_role author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Magalhães, Sara
Sucena, Élio
dc.subject.por.fl_str_mv adaptation
genomics/proteomics
host-parasite interactions
insects
quantitative genetics
topic adaptation
genomics/proteomics
host-parasite interactions
insects
quantitative genetics
description The deposited article is a post-print version and has peer-review. There are no funders and sponsors indicated explicitly in the document. There is no public supplementary material available. This publication hasn't any creative commons license associated.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-07
2016-10-07T00:00:00Z
2017-11-02T17:47:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/797
url http://hdl.handle.net/10400.7/797
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Magalhães, S. and Sucena, É. (2016), Genetics of host–parasite interactions: towards a comprehensive dissection of Drosophila resistance to viral infection. Mol Ecol, 25: 4981–4983. doi:10.1111/mec.13834
10.1111/mec.13834
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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