Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline

Detalhes bibliográficos
Autor(a) principal: Ferreira, Ana Maria
Data de Publicação: 2020
Outros Autores: Santos, Joana Caldeira, Ferreira, Sofia, Leite, Ana Luísa, Campos, Rosa Arménia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934
Resumo: Acute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context.
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spelling Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertralinePancreatite e cetoacidose diabética numa adolescente tratada com sertralinaCase ReportsAcute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context.A pancreatite aguda (PA) é uma entidade rara em idade pediátrica. Estão descritos casos clínicos que evidenciam uma associação entre PA e cetoacidose diabética (CAD), postulando o papel da hiperlipidemia transitória como um fator consequente. A etiologia farmacológica é responsável por 0.3−1.4% dos casos de PA, não existindo até o momento casos descritos na literatura que associem a condição ao uso de sertralina na população pediátrica. Os autores descrevem o caso de uma adolescente de 15 anos de idade com diabetes mellitus tipo 1 mal controlada, medicada com sertralina devido a um transtorno depressivo, que desenvolveu PA associada a CAD. Com este caso, os autores pretendem enfatizar a importância do diagnóstico de PA no contexto de CAD. Adicionalmente, dado que a adolescente apresentava níveis séricos de triglicerídeos normais e nenhum outro fator de risco para o desenvolvimento de PA, especula-se que o uso de sertralina pode ter atuado como um evento desencadeante neste contexto.Centro Hospitalar Universitário do Porto2020-11-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934eng2183-9417Ferreira, Ana MariaSantos, Joana CaldeiraFerreira, SofiaLeite, Ana LuísaCampos, Rosa Arméniainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:34Zoai:ojs.revistas.rcaap.pt:article/17934Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:29.310437Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
Pancreatite e cetoacidose diabética numa adolescente tratada com sertralina
title Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
spellingShingle Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
Ferreira, Ana Maria
Case Reports
title_short Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
title_full Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
title_fullStr Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
title_full_unstemmed Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
title_sort Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
author Ferreira, Ana Maria
author_facet Ferreira, Ana Maria
Santos, Joana Caldeira
Ferreira, Sofia
Leite, Ana Luísa
Campos, Rosa Arménia
author_role author
author2 Santos, Joana Caldeira
Ferreira, Sofia
Leite, Ana Luísa
Campos, Rosa Arménia
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Ferreira, Ana Maria
Santos, Joana Caldeira
Ferreira, Sofia
Leite, Ana Luísa
Campos, Rosa Arménia
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Acute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-26T00:00:00Z
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dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934
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dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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