Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934 |
Resumo: | Acute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context. |
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Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertralinePancreatite e cetoacidose diabética numa adolescente tratada com sertralinaCase ReportsAcute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context.A pancreatite aguda (PA) é uma entidade rara em idade pediátrica. Estão descritos casos clínicos que evidenciam uma associação entre PA e cetoacidose diabética (CAD), postulando o papel da hiperlipidemia transitória como um fator consequente. A etiologia farmacológica é responsável por 0.3−1.4% dos casos de PA, não existindo até o momento casos descritos na literatura que associem a condição ao uso de sertralina na população pediátrica. Os autores descrevem o caso de uma adolescente de 15 anos de idade com diabetes mellitus tipo 1 mal controlada, medicada com sertralina devido a um transtorno depressivo, que desenvolveu PA associada a CAD. Com este caso, os autores pretendem enfatizar a importância do diagnóstico de PA no contexto de CAD. Adicionalmente, dado que a adolescente apresentava níveis séricos de triglicerídeos normais e nenhum outro fator de risco para o desenvolvimento de PA, especula-se que o uso de sertralina pode ter atuado como um evento desencadeante neste contexto.Centro Hospitalar Universitário do Porto2020-11-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934eng2183-9417Ferreira, Ana MariaSantos, Joana CaldeiraFerreira, SofiaLeite, Ana LuísaCampos, Rosa Arméniainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:34Zoai:ojs.revistas.rcaap.pt:article/17934Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:29.310437Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline Pancreatite e cetoacidose diabética numa adolescente tratada com sertralina |
title |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
spellingShingle |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline Ferreira, Ana Maria Case Reports |
title_short |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
title_full |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
title_fullStr |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
title_full_unstemmed |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
title_sort |
Pancreatitis and diabetic ketoacidosis in an adolescent treated with sertraline |
author |
Ferreira, Ana Maria |
author_facet |
Ferreira, Ana Maria Santos, Joana Caldeira Ferreira, Sofia Leite, Ana Luísa Campos, Rosa Arménia |
author_role |
author |
author2 |
Santos, Joana Caldeira Ferreira, Sofia Leite, Ana Luísa Campos, Rosa Arménia |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ferreira, Ana Maria Santos, Joana Caldeira Ferreira, Sofia Leite, Ana Luísa Campos, Rosa Arménia |
dc.subject.por.fl_str_mv |
Case Reports |
topic |
Case Reports |
description |
Acute pancreatitis (AP) is a rare entity in pediatric age. Reports of AP in the context of diabetic ketoacidosis (DKA) have established the role of transient hyperlipemia as a consequent factor. Pharmacological etiology is responsible for 0.3−1.4% of AP cases, with no case reports of an association with the use of sertraline in the pediatric population to date. Herein is described the case of a 15-year-old girl with poorly controlled type 1 diabetes, taking sertraline for a depressive disorder, who developed AP associated with DKA. With this report, the authors intend to emphasize the importance of diagnosing AP in DKA setting. In addition, since the patient had normal serum triglyceride levels and no other risk factors for AP, it is hypothesized that sertraline may have been a triggering event in this context. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-11-26T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934 |
url |
https://doi.org/10.25753/BirthGrowthMJ.v29.i4.17934 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2183-9417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1799130433290502144 |