Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/27115 https://doi.org/10.1016/j.jct.2013.12.010 |
Resumo: | Ternary mutual diffusion coefficients (D11, D22, D12 and D21) measured by the Taylor dispersion method are reported for aqueous solutions of {levodopa (l-dopa) + HCl} solutions at 25 °C and HCl concentrations up to 0.100 mol · dm−3. The coupled diffusion of l-dopa (1) and HCl (2) is significant, as indicated by large negative cross-diffusion coefficients. D21, for example, reaches values that are larger than D11, the main coefficient of l-dopa. Combined Fick and Nernst–Planck equations are used to analyze the proton coupled diffusion of l-dopa and HCl in terms of the binding of H+ ions to l-dopa and ion migration in the electric field generated by l-dopa and HCl concentration gradients. |
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7160 |
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Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °CLevodopaDiffusion coefficientTransport propertiesAqueous solutionsTernary mutual diffusion coefficients (D11, D22, D12 and D21) measured by the Taylor dispersion method are reported for aqueous solutions of {levodopa (l-dopa) + HCl} solutions at 25 °C and HCl concentrations up to 0.100 mol · dm−3. The coupled diffusion of l-dopa (1) and HCl (2) is significant, as indicated by large negative cross-diffusion coefficients. D21, for example, reaches values that are larger than D11, the main coefficient of l-dopa. Combined Fick and Nernst–Planck equations are used to analyze the proton coupled diffusion of l-dopa and HCl in terms of the binding of H+ ions to l-dopa and ion migration in the electric field generated by l-dopa and HCl concentration gradients.Elsevier2014-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/27115http://hdl.handle.net/10316/27115https://doi.org/10.1016/j.jct.2013.12.010engBARROS, Marisa C. F. [et al.] - Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C. "The Journal of Chemical Thermodynamics". ISSN 0021-9614. Vol. 72 (2014) p. 44-470021-9614http://www.sciencedirect.com/science/article/pii/S0021961413004758Barros, Marisa C. F.Ribeiro, Ana C. F.Esteso, Miguel A.Lobo, Victor M. M.Leaist, Derek G.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2020-05-25T13:18:53Zoai:estudogeral.uc.pt:10316/27115Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:01:49.727376Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
title |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
spellingShingle |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C Barros, Marisa C. F. Levodopa Diffusion coefficient Transport properties Aqueous solutions |
title_short |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
title_full |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
title_fullStr |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
title_full_unstemmed |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
title_sort |
Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C |
author |
Barros, Marisa C. F. |
author_facet |
Barros, Marisa C. F. Ribeiro, Ana C. F. Esteso, Miguel A. Lobo, Victor M. M. Leaist, Derek G. |
author_role |
author |
author2 |
Ribeiro, Ana C. F. Esteso, Miguel A. Lobo, Victor M. M. Leaist, Derek G. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barros, Marisa C. F. Ribeiro, Ana C. F. Esteso, Miguel A. Lobo, Victor M. M. Leaist, Derek G. |
dc.subject.por.fl_str_mv |
Levodopa Diffusion coefficient Transport properties Aqueous solutions |
topic |
Levodopa Diffusion coefficient Transport properties Aqueous solutions |
description |
Ternary mutual diffusion coefficients (D11, D22, D12 and D21) measured by the Taylor dispersion method are reported for aqueous solutions of {levodopa (l-dopa) + HCl} solutions at 25 °C and HCl concentrations up to 0.100 mol · dm−3. The coupled diffusion of l-dopa (1) and HCl (2) is significant, as indicated by large negative cross-diffusion coefficients. D21, for example, reaches values that are larger than D11, the main coefficient of l-dopa. Combined Fick and Nernst–Planck equations are used to analyze the proton coupled diffusion of l-dopa and HCl in terms of the binding of H+ ions to l-dopa and ion migration in the electric field generated by l-dopa and HCl concentration gradients. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-05 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/27115 http://hdl.handle.net/10316/27115 https://doi.org/10.1016/j.jct.2013.12.010 |
url |
http://hdl.handle.net/10316/27115 https://doi.org/10.1016/j.jct.2013.12.010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BARROS, Marisa C. F. [et al.] - Diffusion of levodopa in aqueous solutions of hydrochloric acid at 25 °C. "The Journal of Chemical Thermodynamics". ISSN 0021-9614. Vol. 72 (2014) p. 44-47 0021-9614 http://www.sciencedirect.com/science/article/pii/S0021961413004758 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799133908819771392 |