Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water

Detalhes bibliográficos
Autor(a) principal: Magro, Cátia
Data de Publicação: 2022
Outros Autores: Moura, Tiago, Dionísio, Joana, Ribeiro, Paulo A., Raposo, Maria, Sério, Susana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/143324
Resumo: Funding Information: This research was supported in part by Fundação para a Ciência e a Tecnologia (FCT), Por-tugal, through the research center Grants No. UIDB/FIS/04559/2020 and No. UIDP/FIS/04559/2020 (LIBPhys), from FCT/MCTES, Portugal. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Waterantibioticselectronic tongueenvironmental monitoringimpedance spectroscopymetal oxidesnanostructured sensorsChemical Engineering(all)Materials Science(all)SDG 3 - Good Health and Well-beingFunding Information: This research was supported in part by Fundação para a Ciência e a Tecnologia (FCT), Por-tugal, through the research center Grants No. UIDB/FIS/04559/2020 and No. UIDP/FIS/04559/2020 (LIBPhys), from FCT/MCTES, Portugal. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Antibiotics represent a class of pharmaceuticals used to treat bacterial infections. However, the ever-growing use of antibiotics in agriculture and human and veterinary medicine has led to great concern regarding the outbreak of microbe strains resistant to antimicrobial drugs. Azithromycin, clarithromycin, and erythromycin are macrolides, a group of molecules with a broad spectrum of antibiotic properties, included in the second EU watchlist of emerging pollutants which emphasizes the importance of understanding their occurrence, fate, and monitoring in aquatic environments. Thus, the aim of this study was to develop sensors based on nanostructured thin films deposited on ceramic substrates with gold interdigitated electrodes, to detect azithromycin, clarithromycin, and erythromycin in water matrices (mineral and river water). Impedance spectroscopy was employed as the transducing method for the devices’ electrical signal, producing multivariate datasets which were subsequently analyzed by principal component analysis (PCA). The PCA plots for mineral water demonstrated that ZnO-and TiO2-based sensors produced by DC magnetron sputtering either with 50% or 100% O2 in the sputtering chamber, were able to detect the three macrolides in concentrations between 10−15 M and 10−5 M. In river water, the PCA discrimination presented patterns and trends, between non-doped and doped, and sorting the different concentrations of azithromycin, clarithromycin, and erythromycin. Considering both matrices, by applying the e-tongue concept, sensitivity values of 4.8 ± 0.3, 4.6 ± 0.3, and 4.5 ± 0.3 per decade to azithromycin, clarithromycin, and erythromycin concentration, respectively, were achieved. In all cases, a resolution of 1 × 10−16 M was found near the 10−15 M concentration, the lowest antibiotic concentration measured.DF – Departamento de FísicaLIBPhys-UNLRUNMagro, CátiaMoura, TiagoDionísio, JoanaRibeiro, Paulo A.Raposo, MariaSério, Susana2022-08-26T22:17:38Z2022-05-292022-05-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article15application/pdfhttp://hdl.handle.net/10362/143324eng2079-4991PURE: 45375091https://doi.org/10.3390/nano12111858info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:21:39Zoai:run.unl.pt:10362/143324Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:50:53.574756Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
title Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
spellingShingle Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
Magro, Cátia
antibiotics
electronic tongue
environmental monitoring
impedance spectroscopy
metal oxides
nanostructured sensors
Chemical Engineering(all)
Materials Science(all)
SDG 3 - Good Health and Well-being
title_short Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
title_full Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
title_fullStr Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
title_full_unstemmed Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
title_sort Nanostructured Metal Oxide Sensors for Antibiotic Monitoring in Mineral and River Water
author Magro, Cátia
author_facet Magro, Cátia
Moura, Tiago
Dionísio, Joana
Ribeiro, Paulo A.
Raposo, Maria
Sério, Susana
author_role author
author2 Moura, Tiago
Dionísio, Joana
Ribeiro, Paulo A.
Raposo, Maria
Sério, Susana
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv DF – Departamento de Física
LIBPhys-UNL
RUN
dc.contributor.author.fl_str_mv Magro, Cátia
Moura, Tiago
Dionísio, Joana
Ribeiro, Paulo A.
Raposo, Maria
Sério, Susana
dc.subject.por.fl_str_mv antibiotics
electronic tongue
environmental monitoring
impedance spectroscopy
metal oxides
nanostructured sensors
Chemical Engineering(all)
Materials Science(all)
SDG 3 - Good Health and Well-being
topic antibiotics
electronic tongue
environmental monitoring
impedance spectroscopy
metal oxides
nanostructured sensors
Chemical Engineering(all)
Materials Science(all)
SDG 3 - Good Health and Well-being
description Funding Information: This research was supported in part by Fundação para a Ciência e a Tecnologia (FCT), Por-tugal, through the research center Grants No. UIDB/FIS/04559/2020 and No. UIDP/FIS/04559/2020 (LIBPhys), from FCT/MCTES, Portugal. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-26T22:17:38Z
2022-05-29
2022-05-29T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/143324
url http://hdl.handle.net/10362/143324
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-4991
PURE: 45375091
https://doi.org/10.3390/nano12111858
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 15
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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