A Potentially Fatal Aphrodisiac: Cantharidin Poisoning

Detalhes bibliográficos
Autor(a) principal: Diaz, P
Data de Publicação: 2020
Outros Autores: Carneiro, A, Montes, V, Alves, S
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.10/2446
Resumo: Cantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the case of a 51-year old male patient who developed severe cantharidin poisoning after ingesting a preparation ('tea formulation') containing the substance. The patient reported a burning sensation in his oral cavity, diarrhea and hematuria, having sustained acute kidney injury and atypical neurological symptoms. Due to the lack of an antidote, the available treatment options are reduced to supportive measures. This case strengthens the need for a thorough medical history to ascertain the use of 'natural' products and medicinal herbs (i.e. of unregulated origin), and the importance of educating the community to their potential toxicity.
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spelling A Potentially Fatal Aphrodisiac: Cantharidin PoisoningUm Afrodisíaco Potencialmente Fatal: Intoxicação por CantaridinaIntoxicaçãoAfrodisíacosCantaridinaCantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the case of a 51-year old male patient who developed severe cantharidin poisoning after ingesting a preparation ('tea formulation') containing the substance. The patient reported a burning sensation in his oral cavity, diarrhea and hematuria, having sustained acute kidney injury and atypical neurological symptoms. Due to the lack of an antidote, the available treatment options are reduced to supportive measures. This case strengthens the need for a thorough medical history to ascertain the use of 'natural' products and medicinal herbs (i.e. of unregulated origin), and the importance of educating the community to their potential toxicity.A cantaridina é uma toxina extraída de coleópteros, comummente conhecidos como ‘Spanish fly’. Historicamente utilizada como afrodisíaco, vesicante e abortivo. A intoxicação por este agente encontra-se amplamente descrita, tipicamente com envolvimento das mucosas gastrointestinal, com hemorragia digestiva, e genitourinária, com hematúria e lesão renal aguda. Os autores apresentam o caso de um doente do sexo masculino, com 51 anos que desenvolveu um quadro de intoxicação aguda por cantaridina, após ingestão de uma preparação (‘chá’) desta substância, com ardor na cavidade oral, diarreia, disúria, hematúria, lesão renal aguda e com um quadro neurológico atípico. A toxicidade pela cantaridina é sistémica, contudo, o envolvimento neurológico é raro. Dada ausência de um antídoto, preconiza-se a terapêutica de suporte. Este caso reforça a importância de uma anamnese detalhada, incluindo a utilização de produtos ‘naturais’ ou de ervanária (i.e. de origem não controlada), e da necessidade de alertar os doentes para a sua potencial toxicidade.Ordem dos MédicosRepositório do Hospital Prof. Doutor Fernando FonsecaDiaz, PCarneiro, AMontes, VAlves, S2020-07-03T10:57:40Z2020-01-01T00:00:00Z2020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.10/2446porActa Med Port. 2020 Apr 1;33(4):284-2871646-075810.20344/amp.11567info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-20T15:53:07Zoai:repositorio.hff.min-saude.pt:10400.10/2446Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:53:21.783783Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
Um Afrodisíaco Potencialmente Fatal: Intoxicação por Cantaridina
title A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
spellingShingle A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
Diaz, P
Intoxicação
Afrodisíacos
Cantaridina
title_short A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
title_full A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
title_fullStr A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
title_full_unstemmed A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
title_sort A Potentially Fatal Aphrodisiac: Cantharidin Poisoning
author Diaz, P
author_facet Diaz, P
Carneiro, A
Montes, V
Alves, S
author_role author
author2 Carneiro, A
Montes, V
Alves, S
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório do Hospital Prof. Doutor Fernando Fonseca
dc.contributor.author.fl_str_mv Diaz, P
Carneiro, A
Montes, V
Alves, S
dc.subject.por.fl_str_mv Intoxicação
Afrodisíacos
Cantaridina
topic Intoxicação
Afrodisíacos
Cantaridina
description Cantharidin is a toxin extracted from coleoptera beetles, commonly known as 'Spanish fly'. Traditionally it was used as an aphrodisiac, a vesicant or as an abortifacient. Intoxication by this substance has been widely reported, generally associated with gastrointestinal complications, such as digestive hemorrhage, and genitourinary disorders, such as hematuria and acute kidney injury. The authors describe the case of a 51-year old male patient who developed severe cantharidin poisoning after ingesting a preparation ('tea formulation') containing the substance. The patient reported a burning sensation in his oral cavity, diarrhea and hematuria, having sustained acute kidney injury and atypical neurological symptoms. Due to the lack of an antidote, the available treatment options are reduced to supportive measures. This case strengthens the need for a thorough medical history to ascertain the use of 'natural' products and medicinal herbs (i.e. of unregulated origin), and the importance of educating the community to their potential toxicity.
publishDate 2020
dc.date.none.fl_str_mv 2020-07-03T10:57:40Z
2020-01-01T00:00:00Z
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.10/2446
url http://hdl.handle.net/10400.10/2446
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv Acta Med Port. 2020 Apr 1;33(4):284-287
1646-0758
10.20344/amp.11567
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
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instacron_str RCAAP
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