Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/17857 |
Resumo: | Rubella infection can affect several organs and cause birth defects that are responsible for congenital rubella syndrome (CRS). Congenital hearing loss is the most common symptom of this syndrome, occurring in approximately 60% of CRS cases. Worldwide, over 100 000 babies are born with CRS every year. There is no specific treatment for rubella, but the disease is preventable by vaccination. Since 1969, the rubella vaccine has been implemented in many countries, but in Africa, only a few countries routinely immunize against rubella. The aim of this study was to estimate the rate of infection from the wild-type rubella virus in São Tomé and Príncipe by determining rubella seroprevalence with a DBS method. The goal of this study was to reinforce the need for implementation of the rubella vaccine in this country. As secondary objectives, the validation of a DBS method was first attempted and an association between seroprevalence and hearing loss was assessed. |
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Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control studySíndrome de Rubéola CongénitaSurdezÁfrica ao Sul do SaaraPerda Auditiva NeurossensorialDeafnessRubella Syndrome, CongenitalHearing Loss, SensorineuralAfrica South of the SaharaRubella infection can affect several organs and cause birth defects that are responsible for congenital rubella syndrome (CRS). Congenital hearing loss is the most common symptom of this syndrome, occurring in approximately 60% of CRS cases. Worldwide, over 100 000 babies are born with CRS every year. There is no specific treatment for rubella, but the disease is preventable by vaccination. Since 1969, the rubella vaccine has been implemented in many countries, but in Africa, only a few countries routinely immunize against rubella. The aim of this study was to estimate the rate of infection from the wild-type rubella virus in São Tomé and Príncipe by determining rubella seroprevalence with a DBS method. The goal of this study was to reinforce the need for implementation of the rubella vaccine in this country. As secondary objectives, the validation of a DBS method was first attempted and an association between seroprevalence and hearing loss was assessed.Repositório ComumCaroça, CVicente, VCampelo, PChasqueira, MCaria, HSilva, SPaixão, PPaço, J2017-02-05T17:17:39Z2017-02-012017-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/17857engBMC Public Health (2017) 17:14610.1186/s12889-017-4077-2info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:25:08Zoai:comum.rcaap.pt:10400.26/17857Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:22:44.215165Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
title |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
spellingShingle |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study Caroça, C Síndrome de Rubéola Congénita Surdez África ao Sul do Saara Perda Auditiva Neurossensorial Deafness Rubella Syndrome, Congenital Hearing Loss, Sensorineural Africa South of the Sahara |
title_short |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
title_full |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
title_fullStr |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
title_full_unstemmed |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
title_sort |
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study |
author |
Caroça, C |
author_facet |
Caroça, C Vicente, V Campelo, P Chasqueira, M Caria, H Silva, S Paixão, P Paço, J |
author_role |
author |
author2 |
Vicente, V Campelo, P Chasqueira, M Caria, H Silva, S Paixão, P Paço, J |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Caroça, C Vicente, V Campelo, P Chasqueira, M Caria, H Silva, S Paixão, P Paço, J |
dc.subject.por.fl_str_mv |
Síndrome de Rubéola Congénita Surdez África ao Sul do Saara Perda Auditiva Neurossensorial Deafness Rubella Syndrome, Congenital Hearing Loss, Sensorineural Africa South of the Sahara |
topic |
Síndrome de Rubéola Congénita Surdez África ao Sul do Saara Perda Auditiva Neurossensorial Deafness Rubella Syndrome, Congenital Hearing Loss, Sensorineural Africa South of the Sahara |
description |
Rubella infection can affect several organs and cause birth defects that are responsible for congenital rubella syndrome (CRS). Congenital hearing loss is the most common symptom of this syndrome, occurring in approximately 60% of CRS cases. Worldwide, over 100 000 babies are born with CRS every year. There is no specific treatment for rubella, but the disease is preventable by vaccination. Since 1969, the rubella vaccine has been implemented in many countries, but in Africa, only a few countries routinely immunize against rubella. The aim of this study was to estimate the rate of infection from the wild-type rubella virus in São Tomé and Príncipe by determining rubella seroprevalence with a DBS method. The goal of this study was to reinforce the need for implementation of the rubella vaccine in this country. As secondary objectives, the validation of a DBS method was first attempted and an association between seroprevalence and hearing loss was assessed. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-02-05T17:17:39Z 2017-02-01 2017-02-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/17857 |
url |
http://hdl.handle.net/10400.26/17857 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMC Public Health (2017) 17:146 10.1186/s12889-017-4077-2 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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