Potential of Graphene–Polymer composites for ligament and tendon repair: a review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/70373 |
Resumo: | Tendon/ligament injuries are debilitating conditions that affect the life quality of a great percentage of the adult population. Several challenges still have to be addressed regarding the repair of these tissues, as current treatments show limited success. The use of biocompatible and biodegradable polymeric scaffolds potentially helps accomplish a complete and long-term functional repair but, unfortunately, these materials lack adequate mechanical properties to be used in such demanding applications. Graphene is a subject of interest for tissue-repair applications due to its electrical conductivity and mechanical properties. If incorporated adequately, it may significantly improve the physical properties of the composite, even at small loadings. Furthermore, graphene presents a biocompatible surface that may enhance cell adhesion, proliferation and differentiation and demonstrates promising outcomes in several in vitro and in vivo biological applications. Therefore, herein, the potential of graphene materials for the reinforcement of biodegradable polymers of interest for tendon/ligament repair is explored. The effect of graphene on relevant features such as mechanical properties, biodegradability, and biocompatibility is revised, to understand the feasibility of these composites to fulfill the requirements associated with these tissues and conclude how their applicability is extended to this field. |
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Potential of Graphene–Polymer composites for ligament and tendon repair: a reviewbiocompatibility and biodegradabilitycomposite scaffoldsgraphenemechanical propertiestendon and ligament repairCiências Médicas::Biotecnologia MédicaEngenharia e Tecnologia::Engenharia MédicaScience & TechnologyTendon/ligament injuries are debilitating conditions that affect the life quality of a great percentage of the adult population. Several challenges still have to be addressed regarding the repair of these tissues, as current treatments show limited success. The use of biocompatible and biodegradable polymeric scaffolds potentially helps accomplish a complete and long-term functional repair but, unfortunately, these materials lack adequate mechanical properties to be used in such demanding applications. Graphene is a subject of interest for tissue-repair applications due to its electrical conductivity and mechanical properties. If incorporated adequately, it may significantly improve the physical properties of the composite, even at small loadings. Furthermore, graphene presents a biocompatible surface that may enhance cell adhesion, proliferation and differentiation and demonstrates promising outcomes in several in vitro and in vivo biological applications. Therefore, herein, the potential of graphene materials for the reinforcement of biodegradable polymers of interest for tendon/ligament repair is explored. The effect of graphene on relevant features such as mechanical properties, biodegradability, and biocompatibility is revised, to understand the feasibility of these composites to fulfill the requirements associated with these tissues and conclude how their applicability is extended to this field.Portuguese Foundation for Science and Technology (FCT) through the National Funds References UIDB/05256/2020 e UIDP/05256/2020. REQUIMTE-LAQV acknowledges the support of the Portuguese Foundation for Science and Technology (FCT) through the National Funds Reference UIDB/50006/2020. Tânia Peixoto also acknowledges the financial support from FCT, through the PhD Grant PD/BD/143035/2018WileyUniversidade do MinhoPeixoto, TâniaPaiva, M. C.Marques, António T.Lopes, Maria A.2020-122020-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70373engPeixoto, T., Paiva, M. C., Marques, A. T., & Lopes, M. A. (2020). Potential of Graphene–Polymer Composites for Ligament and Tendon Repair: A Review. Advanced Engineering Materials, 22(12), 20004921438-16561527-264810.1002/adem.202000492https://onlinelibrary.wiley.com/doi/abs/10.1002/adem.202000492info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:55:26Zoai:repositorium.sdum.uminho.pt:1822/70373Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:44:59.230887Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
title |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
spellingShingle |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review Peixoto, Tânia biocompatibility and biodegradability composite scaffolds graphene mechanical properties tendon and ligament repair Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Engenharia Médica Science & Technology |
title_short |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
title_full |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
title_fullStr |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
title_full_unstemmed |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
title_sort |
Potential of Graphene–Polymer composites for ligament and tendon repair: a review |
author |
Peixoto, Tânia |
author_facet |
Peixoto, Tânia Paiva, M. C. Marques, António T. Lopes, Maria A. |
author_role |
author |
author2 |
Paiva, M. C. Marques, António T. Lopes, Maria A. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Peixoto, Tânia Paiva, M. C. Marques, António T. Lopes, Maria A. |
dc.subject.por.fl_str_mv |
biocompatibility and biodegradability composite scaffolds graphene mechanical properties tendon and ligament repair Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Engenharia Médica Science & Technology |
topic |
biocompatibility and biodegradability composite scaffolds graphene mechanical properties tendon and ligament repair Ciências Médicas::Biotecnologia Médica Engenharia e Tecnologia::Engenharia Médica Science & Technology |
description |
Tendon/ligament injuries are debilitating conditions that affect the life quality of a great percentage of the adult population. Several challenges still have to be addressed regarding the repair of these tissues, as current treatments show limited success. The use of biocompatible and biodegradable polymeric scaffolds potentially helps accomplish a complete and long-term functional repair but, unfortunately, these materials lack adequate mechanical properties to be used in such demanding applications. Graphene is a subject of interest for tissue-repair applications due to its electrical conductivity and mechanical properties. If incorporated adequately, it may significantly improve the physical properties of the composite, even at small loadings. Furthermore, graphene presents a biocompatible surface that may enhance cell adhesion, proliferation and differentiation and demonstrates promising outcomes in several in vitro and in vivo biological applications. Therefore, herein, the potential of graphene materials for the reinforcement of biodegradable polymers of interest for tendon/ligament repair is explored. The effect of graphene on relevant features such as mechanical properties, biodegradability, and biocompatibility is revised, to understand the feasibility of these composites to fulfill the requirements associated with these tissues and conclude how their applicability is extended to this field. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12 2020-12-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/70373 |
url |
http://hdl.handle.net/1822/70373 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Peixoto, T., Paiva, M. C., Marques, A. T., & Lopes, M. A. (2020). Potential of Graphene–Polymer Composites for Ligament and Tendon Repair: A Review. Advanced Engineering Materials, 22(12), 2000492 1438-1656 1527-2648 10.1002/adem.202000492 https://onlinelibrary.wiley.com/doi/abs/10.1002/adem.202000492 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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