Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10314/7423 https://doi.org/10.18549/pharmpract.2020.3.2000 |
Resumo: | Background: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy, which involves a close collaboration between the patient and a multidisciplinary team of which pharmacists should be integral elements. Objective: This work aims to identify and summarize the main effects of interventions carried out by clinical pharmacists in the management of patients with type 2 diabetes, considering clinical, humanistic and economic outcomes. Methods: PubMed and Cochrane Central Register of Controlled Trials were searched for randomized controlled trials assessing the effectiveness of such interventions compared with usual care that took place in hospitals or outpatient facilities. Results: This review included 39 studies, involving a total of 5,474 participants. Beneficial effects were observed on various clinical outcomes such as glycemia, blood pressure, lipid profile, body mass index and coronary heart disease risk. For the following parameters, the range for the difference in change from baseline to final follow-up between the intervention and control groups was: HbA1c, -0.05% to -2.1%; systolic blood pressure, +3.45 mmHg to -10.6 mmHg; total cholesterol, +10.06 mg/dL to -32.48 mg/dL; body mass index, +0.6 kg/m2 to -1.94 kg/m2; and coronary heart disease risk, -3.0% and -12.0% (among the studies that used Framinghan prediction method). The effect on medication adherence and health-related quality of life was also positive. In the studies that performed an economic evaluation, the interventions proved to be economically viable. Conclusions: These findings support and encourage the integration of clinical pharmacists into multidisciplinary teams, underlining their role in improving the management of type 2 diabetes |
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Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic reviewCost-Benefit AnalysisCost-Benefit AnalysisDiabetes MellitusGlycated Hemoglobin AMedication AdherencePharmaceutical ServicesPharmaciesPharmacistsQuality of LifeSystematic Reviews as TopicBackground: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy, which involves a close collaboration between the patient and a multidisciplinary team of which pharmacists should be integral elements. Objective: This work aims to identify and summarize the main effects of interventions carried out by clinical pharmacists in the management of patients with type 2 diabetes, considering clinical, humanistic and economic outcomes. Methods: PubMed and Cochrane Central Register of Controlled Trials were searched for randomized controlled trials assessing the effectiveness of such interventions compared with usual care that took place in hospitals or outpatient facilities. Results: This review included 39 studies, involving a total of 5,474 participants. Beneficial effects were observed on various clinical outcomes such as glycemia, blood pressure, lipid profile, body mass index and coronary heart disease risk. For the following parameters, the range for the difference in change from baseline to final follow-up between the intervention and control groups was: HbA1c, -0.05% to -2.1%; systolic blood pressure, +3.45 mmHg to -10.6 mmHg; total cholesterol, +10.06 mg/dL to -32.48 mg/dL; body mass index, +0.6 kg/m2 to -1.94 kg/m2; and coronary heart disease risk, -3.0% and -12.0% (among the studies that used Framinghan prediction method). The effect on medication adherence and health-related quality of life was also positive. In the studies that performed an economic evaluation, the interventions proved to be economically viable. Conclusions: These findings support and encourage the integration of clinical pharmacists into multidisciplinary teams, underlining their role in improving the management of type 2 diabetes2023-01-20T17:10:25Z2023-01-202020-08-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10314/7423http://hdl.handle.net/10314/7423https://doi.org/10.18549/pharmpract.2020.3.2000eng32922572Pousinho, SarahMorgado, ManuelPlácido, AnaRoque, FátimaFalcão, AmílcarAlves, Gilbertoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-14T02:59:58Zoai:bdigital.ipg.pt:10314/7423Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:44:14.008732Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
title |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
spellingShingle |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review Pousinho, Sarah Cost-Benefit Analysis Cost-Benefit Analysis Diabetes Mellitus Glycated Hemoglobin A Medication Adherence Pharmaceutical Services Pharmacies Pharmacists Quality of Life Systematic Reviews as Topic |
title_short |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
title_full |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
title_fullStr |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
title_full_unstemmed |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
title_sort |
Clinical pharmacists interventions in the management of type 2 diabetes mellitus: a systematic review |
author |
Pousinho, Sarah |
author_facet |
Pousinho, Sarah Morgado, Manuel Plácido, Ana Roque, Fátima Falcão, Amílcar Alves, Gilberto |
author_role |
author |
author2 |
Morgado, Manuel Plácido, Ana Roque, Fátima Falcão, Amílcar Alves, Gilberto |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pousinho, Sarah Morgado, Manuel Plácido, Ana Roque, Fátima Falcão, Amílcar Alves, Gilberto |
dc.subject.por.fl_str_mv |
Cost-Benefit Analysis Cost-Benefit Analysis Diabetes Mellitus Glycated Hemoglobin A Medication Adherence Pharmaceutical Services Pharmacies Pharmacists Quality of Life Systematic Reviews as Topic |
topic |
Cost-Benefit Analysis Cost-Benefit Analysis Diabetes Mellitus Glycated Hemoglobin A Medication Adherence Pharmaceutical Services Pharmacies Pharmacists Quality of Life Systematic Reviews as Topic |
description |
Background: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy, which involves a close collaboration between the patient and a multidisciplinary team of which pharmacists should be integral elements. Objective: This work aims to identify and summarize the main effects of interventions carried out by clinical pharmacists in the management of patients with type 2 diabetes, considering clinical, humanistic and economic outcomes. Methods: PubMed and Cochrane Central Register of Controlled Trials were searched for randomized controlled trials assessing the effectiveness of such interventions compared with usual care that took place in hospitals or outpatient facilities. Results: This review included 39 studies, involving a total of 5,474 participants. Beneficial effects were observed on various clinical outcomes such as glycemia, blood pressure, lipid profile, body mass index and coronary heart disease risk. For the following parameters, the range for the difference in change from baseline to final follow-up between the intervention and control groups was: HbA1c, -0.05% to -2.1%; systolic blood pressure, +3.45 mmHg to -10.6 mmHg; total cholesterol, +10.06 mg/dL to -32.48 mg/dL; body mass index, +0.6 kg/m2 to -1.94 kg/m2; and coronary heart disease risk, -3.0% and -12.0% (among the studies that used Framinghan prediction method). The effect on medication adherence and health-related quality of life was also positive. In the studies that performed an economic evaluation, the interventions proved to be economically viable. Conclusions: These findings support and encourage the integration of clinical pharmacists into multidisciplinary teams, underlining their role in improving the management of type 2 diabetes |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-28T00:00:00Z 2023-01-20T17:10:25Z 2023-01-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10314/7423 http://hdl.handle.net/10314/7423 https://doi.org/10.18549/pharmpract.2020.3.2000 |
url |
http://hdl.handle.net/10314/7423 https://doi.org/10.18549/pharmpract.2020.3.2000 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
32922572 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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