Optimal time for constant drug infusion initialization in neuromuscular blockade control

Detalhes bibliográficos
Autor(a) principal: Angela Miranda
Data de Publicação: 2014
Outros Autores: Teresa Mendonca, Rocha, P
Tipo de documento: Livro
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://repositorio-aberto.up.pt/handle/10216/110088
Resumo: This paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.
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spelling Optimal time for constant drug infusion initialization in neuromuscular blockade controlBiotecnologia ambientalEnvironmental biotechnologyThis paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookapplication/pdfhttps://repositorio-aberto.up.pt/handle/10216/110088eng10.1109/memea.2014.6860068Angela MirandaTeresa MendoncaRocha, Pinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T14:07:52Zoai:repositorio-aberto.up.pt:10216/110088Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:55:34.172768Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Optimal time for constant drug infusion initialization in neuromuscular blockade control
title Optimal time for constant drug infusion initialization in neuromuscular blockade control
spellingShingle Optimal time for constant drug infusion initialization in neuromuscular blockade control
Angela Miranda
Biotecnologia ambiental
Environmental biotechnology
title_short Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_full Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_fullStr Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_full_unstemmed Optimal time for constant drug infusion initialization in neuromuscular blockade control
title_sort Optimal time for constant drug infusion initialization in neuromuscular blockade control
author Angela Miranda
author_facet Angela Miranda
Teresa Mendonca
Rocha, P
author_role author
author2 Teresa Mendonca
Rocha, P
author2_role author
author
dc.contributor.author.fl_str_mv Angela Miranda
Teresa Mendonca
Rocha, P
dc.subject.por.fl_str_mv Biotecnologia ambiental
Environmental biotechnology
topic Biotecnologia ambiental
Environmental biotechnology
description This paper presents a control strategy for neuromuscular blockade (NMB) level, in order to determine the optimal time to initialize the administration of the muscle relaxant rocuronium by means of the continuous infusion of a constant dose. The constant value of muscle relaxant for a particular patient undergoing general anesthesia is computed in order to guarantee that the steady-state value of neuromuscular blockade level is the desired reference value. In order to apply this open-loop control strategy, the patient's NMB response to rocuronium is assumed to be modeled by a recently proposed parameter parsimonious model.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/book
format book
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio-aberto.up.pt/handle/10216/110088
url https://repositorio-aberto.up.pt/handle/10216/110088
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1109/memea.2014.6860068
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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