Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins

Detalhes bibliográficos
Autor(a) principal: Pena, Angelina
Data de Publicação: 2021
Outros Autores: Duarte, Sofia, Pereira, André M. P. T., Silva, Liliana J. G., Laranjeiro, Célia S. M., Oliveira, Marta, Lino, Celeste, Morais, Simone
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/21999
Resumo: Human biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by means of determining the parent compounds, their metabolites, or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are dispersed and limited. Thus, to overcome this knowledge gap, this work reviews the published Portuguese HBM information concerning mycotoxins detected in the urine, serum, milk, hair, and nails of different groups of the Portuguese population. This integrative approach to the available HBM data allows us to analyze the main determinants and patterns of exposure of the Portuguese population to the selected hazardous compounds, as well as to assess the potential health risks. We also aimed to identify the main difficulties and challenges of HBM through the analysis of the enrolled studies. Ultimately, this study aims to support national and European policies in promoting human health by summarizing the most important outcomes and lessons learned through the HBM studies carried out in Portugal
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spelling Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on MycotoxinsBiomarkers of exposureMycotoxinsHealth risksHuman biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by means of determining the parent compounds, their metabolites, or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are dispersed and limited. Thus, to overcome this knowledge gap, this work reviews the published Portuguese HBM information concerning mycotoxins detected in the urine, serum, milk, hair, and nails of different groups of the Portuguese population. This integrative approach to the available HBM data allows us to analyze the main determinants and patterns of exposure of the Portuguese population to the selected hazardous compounds, as well as to assess the potential health risks. We also aimed to identify the main difficulties and challenges of HBM through the analysis of the enrolled studies. Ultimately, this study aims to support national and European policies in promoting human health by summarizing the most important outcomes and lessons learned through the HBM studies carried out in PortugalThis work received financial support from European (FEDER funds through COMPETE) and National (Fundação para a Ciência e Tecnologia project UIDB/QUI/50006/2020) funds. The authors are also grateful to the Fundação para a Ciência e Tecnologia (FCT) for the financial support through the projects “PCIF/SSO/0017/2018-A panel of (bio)markers for the surveillance of firefighter’s health and safety” and “PCIF/SSO/0090/2019-Firefighting occupational exposure and early effects on the health of operational forces”, which are funded by Portuguese National Funds. M. Oliveira thanks FCT/MCTES for the CEEC-Individual 2017 Program Contract: CEECIND/03666/2017. L. Silva thanks FCT/MCTES for funding through program DL 57/2016—Norma transitória (REF. DL-57-2016/ICETA/02)MDPIRepositório Científico do Instituto Politécnico do PortoPena, AngelinaDuarte, SofiaPereira, André M. P. T.Silva, Liliana J. G.Laranjeiro, Célia S. M.Oliveira, MartaLino, CelesteMorais, Simone2023-01-30T11:45:05Z2021-12-212021-12-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/21999eng10.3390/molecules27010130info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:18:21Zoai:recipp.ipp.pt:10400.22/21999Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:42:04.087905Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
title Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
spellingShingle Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
Pena, Angelina
Biomarkers of exposure
Mycotoxins
Health risks
title_short Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
title_full Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
title_fullStr Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
title_full_unstemmed Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
title_sort Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II—Lessons Learned on Mycotoxins
author Pena, Angelina
author_facet Pena, Angelina
Duarte, Sofia
Pereira, André M. P. T.
Silva, Liliana J. G.
Laranjeiro, Célia S. M.
Oliveira, Marta
Lino, Celeste
Morais, Simone
author_role author
author2 Duarte, Sofia
Pereira, André M. P. T.
Silva, Liliana J. G.
Laranjeiro, Célia S. M.
Oliveira, Marta
Lino, Celeste
Morais, Simone
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Pena, Angelina
Duarte, Sofia
Pereira, André M. P. T.
Silva, Liliana J. G.
Laranjeiro, Célia S. M.
Oliveira, Marta
Lino, Celeste
Morais, Simone
dc.subject.por.fl_str_mv Biomarkers of exposure
Mycotoxins
Health risks
topic Biomarkers of exposure
Mycotoxins
Health risks
description Human biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by means of determining the parent compounds, their metabolites, or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are dispersed and limited. Thus, to overcome this knowledge gap, this work reviews the published Portuguese HBM information concerning mycotoxins detected in the urine, serum, milk, hair, and nails of different groups of the Portuguese population. This integrative approach to the available HBM data allows us to analyze the main determinants and patterns of exposure of the Portuguese population to the selected hazardous compounds, as well as to assess the potential health risks. We also aimed to identify the main difficulties and challenges of HBM through the analysis of the enrolled studies. Ultimately, this study aims to support national and European policies in promoting human health by summarizing the most important outcomes and lessons learned through the HBM studies carried out in Portugal
publishDate 2021
dc.date.none.fl_str_mv 2021-12-21
2021-12-21T00:00:00Z
2023-01-30T11:45:05Z
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/molecules27010130
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