Detrimental role of prolonged sleep deprivation on adult neurogenesis

Detalhes bibliográficos
Autor(a) principal: Fernandes, Carina
Data de Publicação: 2015
Outros Autores: Rocha, Nuno, Rocha, Susana, Herrera-Solís, Andrea, Salas-Pacheco, José, García-García, Fabio, Murillo-Rodríguez, Eric, Yuan, Ti-Fei, Machado, Sergio, Arias-Carrión, Oscar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/7336
Resumo: Adult mammalian brains continuously generate new neurons, a phenomenon called adult neurogenesis. Both environmental stimuli and endogenous factors are important regulators of adult neurogenesis. Sleep has an important role in normal brain physiology and its disturbance causes very stressful conditions, which disrupt normal brain physiology. Recently, an influence of sleep in adult neurogenesis has been established, mainly based on sleep deprivation studies. This review provides an overview on how rhythms and sleep cycles regulate hippocampal and subventricular zone neurogenesis, discussing some potential underlying mechanisms. In addition, our review highlights some interacting points between sleep and adult neurogenesis in brain function, such as learning, memory, and mood states, and provides some insights on the effects of antidepressants and hypnotic drugs on adult neurogenesis.
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spelling Detrimental role of prolonged sleep deprivation on adult neurogenesissleepadult neurogenesishypnotic drugsantidepressantscircadian rhythmshippocampusAdult mammalian brains continuously generate new neurons, a phenomenon called adult neurogenesis. Both environmental stimuli and endogenous factors are important regulators of adult neurogenesis. Sleep has an important role in normal brain physiology and its disturbance causes very stressful conditions, which disrupt normal brain physiology. Recently, an influence of sleep in adult neurogenesis has been established, mainly based on sleep deprivation studies. This review provides an overview on how rhythms and sleep cycles regulate hippocampal and subventricular zone neurogenesis, discussing some potential underlying mechanisms. In addition, our review highlights some interacting points between sleep and adult neurogenesis in brain function, such as learning, memory, and mood states, and provides some insights on the effects of antidepressants and hypnotic drugs on adult neurogenesis.Repositório Científico do Instituto Politécnico do PortoFernandes, CarinaRocha, NunoRocha, SusanaHerrera-Solís, AndreaSalas-Pacheco, JoséGarcía-García, FabioMurillo-Rodríguez, EricYuan, Ti-FeiMachado, SergioArias-Carrión, Oscar2016-01-08T11:33:20Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/7336eng10.3389/fncel.2015.00140info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:47:47Zoai:recipp.ipp.pt:10400.22/7336Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:27:49.729091Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Detrimental role of prolonged sleep deprivation on adult neurogenesis
title Detrimental role of prolonged sleep deprivation on adult neurogenesis
spellingShingle Detrimental role of prolonged sleep deprivation on adult neurogenesis
Fernandes, Carina
sleep
adult neurogenesis
hypnotic drugs
antidepressants
circadian rhythms
hippocampus
title_short Detrimental role of prolonged sleep deprivation on adult neurogenesis
title_full Detrimental role of prolonged sleep deprivation on adult neurogenesis
title_fullStr Detrimental role of prolonged sleep deprivation on adult neurogenesis
title_full_unstemmed Detrimental role of prolonged sleep deprivation on adult neurogenesis
title_sort Detrimental role of prolonged sleep deprivation on adult neurogenesis
author Fernandes, Carina
author_facet Fernandes, Carina
Rocha, Nuno
Rocha, Susana
Herrera-Solís, Andrea
Salas-Pacheco, José
García-García, Fabio
Murillo-Rodríguez, Eric
Yuan, Ti-Fei
Machado, Sergio
Arias-Carrión, Oscar
author_role author
author2 Rocha, Nuno
Rocha, Susana
Herrera-Solís, Andrea
Salas-Pacheco, José
García-García, Fabio
Murillo-Rodríguez, Eric
Yuan, Ti-Fei
Machado, Sergio
Arias-Carrión, Oscar
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Fernandes, Carina
Rocha, Nuno
Rocha, Susana
Herrera-Solís, Andrea
Salas-Pacheco, José
García-García, Fabio
Murillo-Rodríguez, Eric
Yuan, Ti-Fei
Machado, Sergio
Arias-Carrión, Oscar
dc.subject.por.fl_str_mv sleep
adult neurogenesis
hypnotic drugs
antidepressants
circadian rhythms
hippocampus
topic sleep
adult neurogenesis
hypnotic drugs
antidepressants
circadian rhythms
hippocampus
description Adult mammalian brains continuously generate new neurons, a phenomenon called adult neurogenesis. Both environmental stimuli and endogenous factors are important regulators of adult neurogenesis. Sleep has an important role in normal brain physiology and its disturbance causes very stressful conditions, which disrupt normal brain physiology. Recently, an influence of sleep in adult neurogenesis has been established, mainly based on sleep deprivation studies. This review provides an overview on how rhythms and sleep cycles regulate hippocampal and subventricular zone neurogenesis, discussing some potential underlying mechanisms. In addition, our review highlights some interacting points between sleep and adult neurogenesis in brain function, such as learning, memory, and mood states, and provides some insights on the effects of antidepressants and hypnotic drugs on adult neurogenesis.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2016-01-08T11:33:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/7336
url http://hdl.handle.net/10400.22/7336
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3389/fncel.2015.00140
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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