Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/1822/79389 |
Resumo: | This study describes the translational potential of the pneumococcal endolysin MSlys as a novel approach to uniquely target and kill Streptococcus pneumoniae causing ocular infections. |
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Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlysThis study describes the translational potential of the pneumococcal endolysin MSlys as a novel approach to uniquely target and kill Streptococcus pneumoniae causing ocular infections.This study was partially supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2020 unit. MDS was supported from a FCT doctoral fellowship, reference SFRH/BD/128825/2017. CA was supported by a scholarship from Fondation pour la Recherche Médicale (FDM202006011203). This work was also supported in part by the New England Corneal Transplant Research Fund (PJMB). Funding agencies had no role in study design, data analysis, decision to publish or preparation of the manuscript.info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoSilva, Maria DanielaAndré, CamilleBispo, Paulo J. M.2022-122022-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/79389engSilva, Maria Daniela; André, Camille; Bispo, Paulo J. M., Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys. Ophthalmology Science, 2(4), 100193, 20222666-914510.1016/j.xops.2022.100193100193https://www.sciencedirect.com/journal/ophthalmology-scienceinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:13:30Zoai:repositorium.sdum.uminho.pt:1822/79389Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:05:35.628178Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
title |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
spellingShingle |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys Silva, Maria Daniela |
title_short |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
title_full |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
title_fullStr |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
title_full_unstemmed |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
title_sort |
Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys |
author |
Silva, Maria Daniela |
author_facet |
Silva, Maria Daniela André, Camille Bispo, Paulo J. M. |
author_role |
author |
author2 |
André, Camille Bispo, Paulo J. M. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Silva, Maria Daniela André, Camille Bispo, Paulo J. M. |
description |
This study describes the translational potential of the pneumococcal endolysin MSlys as a novel approach to uniquely target and kill Streptococcus pneumoniae causing ocular infections. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12 2022-12-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/79389 |
url |
https://hdl.handle.net/1822/79389 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Silva, Maria Daniela; André, Camille; Bispo, Paulo J. M., Targeted killing of ocular Streptococcus pneumoniae by the phage endolysin MSlys. Ophthalmology Science, 2(4), 100193, 2022 2666-9145 10.1016/j.xops.2022.100193 100193 https://www.sciencedirect.com/journal/ophthalmology-science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132468659355648 |