Molecular evolution of the period gene and phylogeny of neotropical sandflies
Autor(a) principal: | |
---|---|
Data de Publicação: | 2002 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/33483 |
Resumo: | The molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regions analyzed. The differences in rate were higher in the sequences flanking the Thr-Gly repetitive domain, a region that has expanded in Drosophila but remained stable and short in sandflies, a result consistent with the coevolutionary scenario proposed for this region of the gene. An initial phylogenetic analysis including eight neotropical sandfly species and one from the Old World was also carried out. The results showed that only the subgenus Nyssomyia is well supported by distance (neighbor-joining) and maximum parsimony analysis. The grouping of the other species from the subgenus Lutzomyia and Migonei group shows very low bootstrap values and is not entirely consistent with classical morphological systematics of the genus Lutzomyia. |
id |
RCAP_b6695202c1a5c924fec993c0db0dc6ae |
---|---|
oai_identifier_str |
oai:comum.rcaap.pt:10400.26/33483 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Molecular evolution of the period gene and phylogeny of neotropical sandfliesRelógios biológicosProteínas de DrosophilaDados de sequência molecularProteínas nuclearesProteínas circadianas periodFilogeniaPsychodidaeHomologia de sequência de aminoácidosHomologia de sequência do ácido nucleicoEvolução molecularGenes de insetosBiological clocksPeriod geneLeishmanioseLeishmaniasisDrosophila proteinsMolecular sequence dataNuclear proteinsPeriod circadian proteinsPhylogenyAmino acid sequence homologyNucleic acid sequence homologyMolecular evolutionInsect genesThe molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regions analyzed. The differences in rate were higher in the sequences flanking the Thr-Gly repetitive domain, a region that has expanded in Drosophila but remained stable and short in sandflies, a result consistent with the coevolutionary scenario proposed for this region of the gene. An initial phylogenetic analysis including eight neotropical sandfly species and one from the Old World was also carried out. The results showed that only the subgenus Nyssomyia is well supported by distance (neighbor-joining) and maximum parsimony analysis. The grouping of the other species from the subgenus Lutzomyia and Migonei group shows very low bootstrap values and is not entirely consistent with classical morphological systematics of the genus Lutzomyia.Springer VerlagRepositório ComumMazzoni, C.J.Alcobia Gomes, Célia MargaridaSouza, N.A.Queiroz, R.G.Justiniano, S.C.B.Ward, R.D.Kyriacou, C.P.Peixoto, Alexandre Afrânio2020-10-02T15:51:35Z2002-11-01T00:00:00Z2002-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/33483eng0022-284410.1007/s00239-002-2351-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T15:41:12Zoai:comum.rcaap.pt:10400.26/33483Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:16:58.806411Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
title |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
spellingShingle |
Molecular evolution of the period gene and phylogeny of neotropical sandflies Mazzoni, C.J. Relógios biológicos Proteínas de Drosophila Dados de sequência molecular Proteínas nucleares Proteínas circadianas period Filogenia Psychodidae Homologia de sequência de aminoácidos Homologia de sequência do ácido nucleico Evolução molecular Genes de insetos Biological clocks Period gene Leishmaniose Leishmaniasis Drosophila proteins Molecular sequence data Nuclear proteins Period circadian proteins Phylogeny Amino acid sequence homology Nucleic acid sequence homology Molecular evolution Insect genes |
title_short |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
title_full |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
title_fullStr |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
title_full_unstemmed |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
title_sort |
Molecular evolution of the period gene and phylogeny of neotropical sandflies |
author |
Mazzoni, C.J. |
author_facet |
Mazzoni, C.J. Alcobia Gomes, Célia Margarida Souza, N.A. Queiroz, R.G. Justiniano, S.C.B. Ward, R.D. Kyriacou, C.P. Peixoto, Alexandre Afrânio |
author_role |
author |
author2 |
Alcobia Gomes, Célia Margarida Souza, N.A. Queiroz, R.G. Justiniano, S.C.B. Ward, R.D. Kyriacou, C.P. Peixoto, Alexandre Afrânio |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Mazzoni, C.J. Alcobia Gomes, Célia Margarida Souza, N.A. Queiroz, R.G. Justiniano, S.C.B. Ward, R.D. Kyriacou, C.P. Peixoto, Alexandre Afrânio |
dc.subject.por.fl_str_mv |
Relógios biológicos Proteínas de Drosophila Dados de sequência molecular Proteínas nucleares Proteínas circadianas period Filogenia Psychodidae Homologia de sequência de aminoácidos Homologia de sequência do ácido nucleico Evolução molecular Genes de insetos Biological clocks Period gene Leishmaniose Leishmaniasis Drosophila proteins Molecular sequence data Nuclear proteins Period circadian proteins Phylogeny Amino acid sequence homology Nucleic acid sequence homology Molecular evolution Insect genes |
topic |
Relógios biológicos Proteínas de Drosophila Dados de sequência molecular Proteínas nucleares Proteínas circadianas period Filogenia Psychodidae Homologia de sequência de aminoácidos Homologia de sequência do ácido nucleico Evolução molecular Genes de insetos Biological clocks Period gene Leishmaniose Leishmaniasis Drosophila proteins Molecular sequence data Nuclear proteins Period circadian proteins Phylogeny Amino acid sequence homology Nucleic acid sequence homology Molecular evolution Insect genes |
description |
The molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regions analyzed. The differences in rate were higher in the sequences flanking the Thr-Gly repetitive domain, a region that has expanded in Drosophila but remained stable and short in sandflies, a result consistent with the coevolutionary scenario proposed for this region of the gene. An initial phylogenetic analysis including eight neotropical sandfly species and one from the Old World was also carried out. The results showed that only the subgenus Nyssomyia is well supported by distance (neighbor-joining) and maximum parsimony analysis. The grouping of the other species from the subgenus Lutzomyia and Migonei group shows very low bootstrap values and is not entirely consistent with classical morphological systematics of the genus Lutzomyia. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-11-01T00:00:00Z 2002-11-01T00:00:00Z 2020-10-02T15:51:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/33483 |
url |
http://hdl.handle.net/10400.26/33483 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0022-2844 10.1007/s00239-002-2351-z |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Springer Verlag |
publisher.none.fl_str_mv |
Springer Verlag |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130032851910656 |