Preparing and selecting actions with neural populations: toward cortical circuit mechanisms

Detalhes bibliográficos
Autor(a) principal: Murakami, Masayoshi
Data de Publicação: 2015
Outros Autores: Mainen, Zachary F
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/23194
Resumo: How the brain selects one action among multiple alternatives is a central question of neuroscience. An influential model is that action preparation and selection arise from subthreshold activation of the very neurons encoding the action. Recent work, however, shows a much greater diversity of decision-related and action-related signals coexisting with other signals in populations of motor and parietal cortical neurons. We discuss how such distributed signals might be decoded by biologically plausible mechanisms. We also discuss how neurons within cortical circuits might interact with each other during action selection and preparation and how recurrent network models can help to reveal dynamical principles underlying cortical computation.
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spelling Preparing and selecting actions with neural populations: toward cortical circuit mechanismsCerebral CortexDecision MakingModels, NeurologicalHow the brain selects one action among multiple alternatives is a central question of neuroscience. An influential model is that action preparation and selection arise from subthreshold activation of the very neurons encoding the action. Recent work, however, shows a much greater diversity of decision-related and action-related signals coexisting with other signals in populations of motor and parietal cortical neurons. We discuss how such distributed signals might be decoded by biologically plausible mechanisms. We also discuss how neurons within cortical circuits might interact with each other during action selection and preparation and how recurrent network models can help to reveal dynamical principles underlying cortical computation.ERC 250334, 5-HT OptogeneticRepositório ComumMurakami, MasayoshiMainen, Zachary F2018-06-29T15:25:42Z2015-02-032015-02-03T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/23194eng10.1016/j.conb.2015.01.005info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-04-12T17:15:13Zoai:comum.rcaap.pt:10400.26/23194Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:49:01.387534Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
title Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
spellingShingle Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
Murakami, Masayoshi
Cerebral Cortex
Decision Making
Models, Neurological
title_short Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
title_full Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
title_fullStr Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
title_full_unstemmed Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
title_sort Preparing and selecting actions with neural populations: toward cortical circuit mechanisms
author Murakami, Masayoshi
author_facet Murakami, Masayoshi
Mainen, Zachary F
author_role author
author2 Mainen, Zachary F
author2_role author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Murakami, Masayoshi
Mainen, Zachary F
dc.subject.por.fl_str_mv Cerebral Cortex
Decision Making
Models, Neurological
topic Cerebral Cortex
Decision Making
Models, Neurological
description How the brain selects one action among multiple alternatives is a central question of neuroscience. An influential model is that action preparation and selection arise from subthreshold activation of the very neurons encoding the action. Recent work, however, shows a much greater diversity of decision-related and action-related signals coexisting with other signals in populations of motor and parietal cortical neurons. We discuss how such distributed signals might be decoded by biologically plausible mechanisms. We also discuss how neurons within cortical circuits might interact with each other during action selection and preparation and how recurrent network models can help to reveal dynamical principles underlying cortical computation.
publishDate 2015
dc.date.none.fl_str_mv 2015-02-03
2015-02-03T00:00:00Z
2018-06-29T15:25:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/23194
url http://hdl.handle.net/10400.26/23194
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.conb.2015.01.005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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