Treatment of acute migraine and status migrainosus in pediatrics
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15431 |
Resumo: | Migraine is the most common acute and recurrent headache syndrome in children and adolescents but is often underdiagnosed. Migraine diagnosis in childhood rests on criteria similar to those used in adults but with some particularities, as duration of the attack, which is often much shorter than in adults, and location of the attack, which in many children may be bilateral. Despite its high prevalence, pediatric migraine remains undertreated, sometimes due to fear of caregivers and physicians and lack of studies about its treatment. Although treatment options for pediatric migraine are increasing, they remain limited. In this article, the authors review approved and “off-label” drugs currently used in migraine and status migrainosus acute treatment in pediatric patients. In migraine treatment, nonsteroidal anti-inflammatory drugs (NSAIDs) should be used. In moderate-to-severe migraine unresponsive to analgesics or NSAIDs, triptans may be used, alone or in combination with the former. Rescue medication, including dihydroergotamine and sodium valproate, can be used in hospital setting for intractable migraine. Antiemetics with anti-dopaminergic properties may be helpful in patients with symptoms of nausea and vomiting in addition to headache, particularly when used in combination therapy. |
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Treatment of acute migraine and status migrainosus in pediatricsTratamento agudo da enxaqueca e do estado de mal de enxaqueca em pediatriaReview ArticlesMigraine is the most common acute and recurrent headache syndrome in children and adolescents but is often underdiagnosed. Migraine diagnosis in childhood rests on criteria similar to those used in adults but with some particularities, as duration of the attack, which is often much shorter than in adults, and location of the attack, which in many children may be bilateral. Despite its high prevalence, pediatric migraine remains undertreated, sometimes due to fear of caregivers and physicians and lack of studies about its treatment. Although treatment options for pediatric migraine are increasing, they remain limited. In this article, the authors review approved and “off-label” drugs currently used in migraine and status migrainosus acute treatment in pediatric patients. In migraine treatment, nonsteroidal anti-inflammatory drugs (NSAIDs) should be used. In moderate-to-severe migraine unresponsive to analgesics or NSAIDs, triptans may be used, alone or in combination with the former. Rescue medication, including dihydroergotamine and sodium valproate, can be used in hospital setting for intractable migraine. Antiemetics with anti-dopaminergic properties may be helpful in patients with symptoms of nausea and vomiting in addition to headache, particularly when used in combination therapy.A enxaqueca é a cefaleia aguda e recorrente mais comum em crianças e adolescentes, mantendo-se, no entanto, subdiagnosticada. O diagnóstico de enxaqueca na infância baseia-se em critérios semelhantes aos utilizados em adultos, mas com algumas particularidades, tais como a duração da cefaleia, que geralmente é muito menor do que no adulto, e a sua localização, que pode muitas vezes ser bilateral. Apesar da elevada prevalência, a enxaqueca pediátrica continua a ser subtratada, por vezes devido a receio dos cuidadores e médicos e à falta de estudos sobre o seu tratamento. Embora as opções de tratamento para a enxaqueca pediátrica tenham vindo a aumentar, permanecem limitadas. Neste artigo, os autores apresentam uma revisão dos fármacos atualmente aprovados e utilizados “off-label” para o tratamento agudo da enxaqueca e do estado de mal de enxaqueca em pediatria. No tratamento da enxaqueca devem ser usados anti-inflamatórios não-esteroides (AINEs). Na enxaqueca moderada a grave que não responde a analgésicos ou AINEs, podem ser utilizados triptanos, isoladamente ou em combinação com aqueles. Medicamentos de resgate, incluindo dihidroergotamina e valproato de sódio, podem ser usados em contexto hospitalar no estado de mal de enxaqueca. Antieméticos com propriedades anti-dopaminérgicas podem ser úteis em doentes com náuseas e vómitos, além de cefaleia, especialmente quando usados em combinação com outros fármacos.Centro Hospitalar Universitário do Porto2019-10-14T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v28.i3.15431eng2183-9417Azevedo Alves, RaquelLopes, MartaRocha, RubenCarrilho, Inêsinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:32Zoai:ojs.revistas.rcaap.pt:article/15431Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:28.125788Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Treatment of acute migraine and status migrainosus in pediatrics Tratamento agudo da enxaqueca e do estado de mal de enxaqueca em pediatria |
title |
Treatment of acute migraine and status migrainosus in pediatrics |
spellingShingle |
Treatment of acute migraine and status migrainosus in pediatrics Azevedo Alves, Raquel Review Articles |
title_short |
Treatment of acute migraine and status migrainosus in pediatrics |
title_full |
Treatment of acute migraine and status migrainosus in pediatrics |
title_fullStr |
Treatment of acute migraine and status migrainosus in pediatrics |
title_full_unstemmed |
Treatment of acute migraine and status migrainosus in pediatrics |
title_sort |
Treatment of acute migraine and status migrainosus in pediatrics |
author |
Azevedo Alves, Raquel |
author_facet |
Azevedo Alves, Raquel Lopes, Marta Rocha, Ruben Carrilho, Inês |
author_role |
author |
author2 |
Lopes, Marta Rocha, Ruben Carrilho, Inês |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Azevedo Alves, Raquel Lopes, Marta Rocha, Ruben Carrilho, Inês |
dc.subject.por.fl_str_mv |
Review Articles |
topic |
Review Articles |
description |
Migraine is the most common acute and recurrent headache syndrome in children and adolescents but is often underdiagnosed. Migraine diagnosis in childhood rests on criteria similar to those used in adults but with some particularities, as duration of the attack, which is often much shorter than in adults, and location of the attack, which in many children may be bilateral. Despite its high prevalence, pediatric migraine remains undertreated, sometimes due to fear of caregivers and physicians and lack of studies about its treatment. Although treatment options for pediatric migraine are increasing, they remain limited. In this article, the authors review approved and “off-label” drugs currently used in migraine and status migrainosus acute treatment in pediatric patients. In migraine treatment, nonsteroidal anti-inflammatory drugs (NSAIDs) should be used. In moderate-to-severe migraine unresponsive to analgesics or NSAIDs, triptans may be used, alone or in combination with the former. Rescue medication, including dihydroergotamine and sodium valproate, can be used in hospital setting for intractable migraine. Antiemetics with anti-dopaminergic properties may be helpful in patients with symptoms of nausea and vomiting in addition to headache, particularly when used in combination therapy. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-14T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15431 |
url |
https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15431 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2183-9417 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
publisher.none.fl_str_mv |
Centro Hospitalar Universitário do Porto |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130433248559104 |