Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors

Detalhes bibliográficos
Autor(a) principal: Carvalho, Ana P. G.
Data de Publicação: 2022
Outros Autores: Alegria, Elisabete C. B. A., Fantoni, Alessandro, Ferraria, Ana M., Do Rego, Ana M. Botelho, Ribeiro, Ana P. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/144485
Resumo: This research was funded by EU funds through the FEDER European Regional Development Fund (project LISBOA-02-0145-FEDER-031311) project LA/P/0056/2020 of Institute of Molecular Sciences, and LA/P/0140/2020 of i4HB, project UID/EEA/00066/2020 from the Center of Technology and Systems, and from the Instituto Politécnico de Lisboa with IPL/2018/STREAM_ISEL and IPL/2020/AGE-SPReS_ISEL projects. APCR and AMF thank the Instituto Superior Técnico for the scientific employment contracts IST-ID/119/2018 and IST-ID/131/2018, respectively. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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spelling Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical BiosensorsA Comparative StudyAuNPsBiosensorsMetal–graphene hybridMie theorySimulationsAnalytical ChemistryBiotechnologyBiomedical EngineeringInstrumentationEngineering (miscellaneous)Clinical BiochemistryThis research was funded by EU funds through the FEDER European Regional Development Fund (project LISBOA-02-0145-FEDER-031311) project LA/P/0056/2020 of Institute of Molecular Sciences, and LA/P/0140/2020 of i4HB, project UID/EEA/00066/2020 from the Center of Technology and Systems, and from the Instituto Politécnico de Lisboa with IPL/2018/STREAM_ISEL and IPL/2020/AGE-SPReS_ISEL projects. APCR and AMF thank the Instituto Superior Técnico for the scientific employment contracts IST-ID/119/2018 and IST-ID/131/2018, respectively. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Aiming to develop a nanoparticle-based optical biosensor using gold nanoparticles (AuNPs) synthesized using green methods and supported by carbon-based nanomaterials, we studied the role of carbon derivatives in promoting AuNPs localized surface plasmon resonance (LSPR), as well as their morphology, dispersion, and stability. Carbon derivatives are expected to work as immobi-lization platforms for AuNPs, improving their analytical performance. Gold nanoparticles (AuNPs) were prepared using an eco-friendly approach in a single step by reduction of HAuCl4·3H2O using phytochemicals (from tea) which act as both reducing and capping agents. UV–Vis spectroscopy, transmission electron microscopy (TEM), zeta potential (ζ-potential), and X-ray photoelectron spectroscopy (XPS) were used to characterize the AuNPs and nanocomposites. The addition of reduced graphene oxide (rGO) resulted in greater dispersion of AuNPs on the rGO surface compared with carbon-based nanomaterials used as a support. Differences in morphology due to the nature of the carbon support were observed and are discussed here. AuNPs/rGO seem to be the most promising candidates for the development of LSPR biosensors among the three composites we studied (AuNPs/G, AuNPs/GO, and AuNPs/rGO). Simulations based on the Mie scattering theory have been used to outline the effect of the phytochemicals on LSPR, showing that when the presence of the residuals is limited to the formation of a thin capping layer, the quality of the plasmonic resonance is not affected. A further discussion of the application framework is presented.CTS - Centro de Tecnologia e SistemasUNINOVA-Instituto de Desenvolvimento de Novas TecnologiasRUNCarvalho, Ana P. G.Alegria, Elisabete C. B. A.Fantoni, AlessandroFerraria, Ana M.Do Rego, Ana M. BotelhoRibeiro, Ana P. C.2022-10-05T22:15:50Z2022-03-042022-03-04T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article20application/pdfhttp://hdl.handle.net/10362/144485eng2079-6374PURE: 46292687https://doi.org/10.3390/bios12030163info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:24:08Zoai:run.unl.pt:10362/144485Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:51:35.501596Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
A Comparative Study
title Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
spellingShingle Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
Carvalho, Ana P. G.
AuNPs
Biosensors
Metal–graphene hybrid
Mie theory
Simulations
Analytical Chemistry
Biotechnology
Biomedical Engineering
Instrumentation
Engineering (miscellaneous)
Clinical Biochemistry
title_short Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
title_full Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
title_fullStr Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
title_full_unstemmed Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
title_sort Effect of Graphene vs. Reduced Graphene Oxide in Gold Nanoparticles for Optical Biosensors
author Carvalho, Ana P. G.
author_facet Carvalho, Ana P. G.
Alegria, Elisabete C. B. A.
Fantoni, Alessandro
Ferraria, Ana M.
Do Rego, Ana M. Botelho
Ribeiro, Ana P. C.
author_role author
author2 Alegria, Elisabete C. B. A.
Fantoni, Alessandro
Ferraria, Ana M.
Do Rego, Ana M. Botelho
Ribeiro, Ana P. C.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv CTS - Centro de Tecnologia e Sistemas
UNINOVA-Instituto de Desenvolvimento de Novas Tecnologias
RUN
dc.contributor.author.fl_str_mv Carvalho, Ana P. G.
Alegria, Elisabete C. B. A.
Fantoni, Alessandro
Ferraria, Ana M.
Do Rego, Ana M. Botelho
Ribeiro, Ana P. C.
dc.subject.por.fl_str_mv AuNPs
Biosensors
Metal–graphene hybrid
Mie theory
Simulations
Analytical Chemistry
Biotechnology
Biomedical Engineering
Instrumentation
Engineering (miscellaneous)
Clinical Biochemistry
topic AuNPs
Biosensors
Metal–graphene hybrid
Mie theory
Simulations
Analytical Chemistry
Biotechnology
Biomedical Engineering
Instrumentation
Engineering (miscellaneous)
Clinical Biochemistry
description This research was funded by EU funds through the FEDER European Regional Development Fund (project LISBOA-02-0145-FEDER-031311) project LA/P/0056/2020 of Institute of Molecular Sciences, and LA/P/0140/2020 of i4HB, project UID/EEA/00066/2020 from the Center of Technology and Systems, and from the Instituto Politécnico de Lisboa with IPL/2018/STREAM_ISEL and IPL/2020/AGE-SPReS_ISEL projects. APCR and AMF thank the Instituto Superior Técnico for the scientific employment contracts IST-ID/119/2018 and IST-ID/131/2018, respectively. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-05T22:15:50Z
2022-03-04
2022-03-04T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/144485
url http://hdl.handle.net/10362/144485
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2079-6374
PURE: 46292687
https://doi.org/10.3390/bios12030163
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 20
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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