Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review

Detalhes bibliográficos
Autor(a) principal: Cipriano, Maria Augusta
Data de Publicação: 2019
Outros Autores: Oliveira, Rui Caetano
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
DOI: 10.21614/sgo-24-6-293
Texto Completo: http://hdl.handle.net/10316/101797
https://doi.org/10.21614/sgo-24-6-293
Resumo: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas are pre neoplastic lesions defined by the World Health Organization as a grossly visible intraductal epithelial neoplasm that arises in the pancreatic ductal system, composed of mucin producing cells. The predisposing factor for their development as well as genetics are still largely unknown. Pathologists have a pivotal role in IPMN management since features like IPMN subtype, degree of atypia, margins status and presence or absence of an invasive component imply different patient management. In this article, we perform a review of the pathological features and molecular markers of IPMNs.
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spelling Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Reviewpancreasintraductal papillary mucinous neoplasmpathology, molecular markersIntraductal papillary mucinous neoplasm (IPMN) of the pancreas are pre neoplastic lesions defined by the World Health Organization as a grossly visible intraductal epithelial neoplasm that arises in the pancreatic ductal system, composed of mucin producing cells. The predisposing factor for their development as well as genetics are still largely unknown. Pathologists have a pivotal role in IPMN management since features like IPMN subtype, degree of atypia, margins status and presence or absence of an invasive component imply different patient management. In this article, we perform a review of the pathological features and molecular markers of IPMNs.2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/101797http://hdl.handle.net/10316/101797https://doi.org/10.21614/sgo-24-6-293eng2559-723XCipriano, Maria AugustaOliveira, Rui Caetanoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-14T20:59:02Zoai:estudogeral.uc.pt:10316/101797Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:18:54.944334Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
title Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
spellingShingle Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
Cipriano, Maria Augusta
pancreas
intraductal papillary mucinous neoplasm
pathology, molecular markers
Cipriano, Maria Augusta
pancreas
intraductal papillary mucinous neoplasm
pathology, molecular markers
title_short Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
title_full Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
title_fullStr Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
title_full_unstemmed Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
title_sort Intraductal Papillary Mucinous Neoplasia of the Pancreas - Pathologic Features and Molecular Markers - A Review
author Cipriano, Maria Augusta
author_facet Cipriano, Maria Augusta
Cipriano, Maria Augusta
Oliveira, Rui Caetano
Oliveira, Rui Caetano
author_role author
author2 Oliveira, Rui Caetano
author2_role author
dc.contributor.author.fl_str_mv Cipriano, Maria Augusta
Oliveira, Rui Caetano
dc.subject.por.fl_str_mv pancreas
intraductal papillary mucinous neoplasm
pathology, molecular markers
topic pancreas
intraductal papillary mucinous neoplasm
pathology, molecular markers
description Intraductal papillary mucinous neoplasm (IPMN) of the pancreas are pre neoplastic lesions defined by the World Health Organization as a grossly visible intraductal epithelial neoplasm that arises in the pancreatic ductal system, composed of mucin producing cells. The predisposing factor for their development as well as genetics are still largely unknown. Pathologists have a pivotal role in IPMN management since features like IPMN subtype, degree of atypia, margins status and presence or absence of an invasive component imply different patient management. In this article, we perform a review of the pathological features and molecular markers of IPMNs.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/101797
http://hdl.handle.net/10316/101797
https://doi.org/10.21614/sgo-24-6-293
url http://hdl.handle.net/10316/101797
https://doi.org/10.21614/sgo-24-6-293
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2559-723X
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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dc.identifier.doi.none.fl_str_mv 10.21614/sgo-24-6-293

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