Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

Detalhes bibliográficos
Autor(a) principal: Vaz, C V
Data de Publicação: 2014
Outros Autores: Baptista, Cláudio, Marques, Ricardo, Gomes, Inês, Correia, Sara, Alves, Marco G, Cavaco, JE, Oliveira, Pedro F., Socorro, Sílvia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/7649
Resumo: Regucalcin (RGN) is a calcium (Ca(2+) )-binding protein underexpressed in prostate adenocarcinoma comparatively to non-neoplastic prostate or benign prostate hyperplasia cases. Moreover, RGN expression is negatively associated with the cellular differentiation of prostate adenocarcinoma, suggesting that loss of RGN may be associated with tumor onset and progression. However, the RGN actions over the control of prostate cell growth have not been investigated.
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spelling Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathwaysAndrogenApoptosisProliferationProstateRegucalcinRegucalcin (RGN) is a calcium (Ca(2+) )-binding protein underexpressed in prostate adenocarcinoma comparatively to non-neoplastic prostate or benign prostate hyperplasia cases. Moreover, RGN expression is negatively associated with the cellular differentiation of prostate adenocarcinoma, suggesting that loss of RGN may be associated with tumor onset and progression. However, the RGN actions over the control of prostate cell growth have not been investigated.uBibliorumVaz, C VBaptista, CláudioMarques, RicardoGomes, InêsCorreia, SaraAlves, Marco GCavaco, JEOliveira, Pedro F.Socorro, Sílvia2019-12-02T16:59:09Z2014-092014-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/7649eng10.1002/pros.22835metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:47:10Zoai:ubibliorum.ubi.pt:10400.6/7649Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:48:07.338011Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
title Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
spellingShingle Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
Vaz, C V
Androgen
Apoptosis
Proliferation
Prostate
Regucalcin
title_short Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
title_full Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
title_fullStr Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
title_full_unstemmed Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
title_sort Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways
author Vaz, C V
author_facet Vaz, C V
Baptista, Cláudio
Marques, Ricardo
Gomes, Inês
Correia, Sara
Alves, Marco G
Cavaco, JE
Oliveira, Pedro F.
Socorro, Sílvia
author_role author
author2 Baptista, Cláudio
Marques, Ricardo
Gomes, Inês
Correia, Sara
Alves, Marco G
Cavaco, JE
Oliveira, Pedro F.
Socorro, Sílvia
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Vaz, C V
Baptista, Cláudio
Marques, Ricardo
Gomes, Inês
Correia, Sara
Alves, Marco G
Cavaco, JE
Oliveira, Pedro F.
Socorro, Sílvia
dc.subject.por.fl_str_mv Androgen
Apoptosis
Proliferation
Prostate
Regucalcin
topic Androgen
Apoptosis
Proliferation
Prostate
Regucalcin
description Regucalcin (RGN) is a calcium (Ca(2+) )-binding protein underexpressed in prostate adenocarcinoma comparatively to non-neoplastic prostate or benign prostate hyperplasia cases. Moreover, RGN expression is negatively associated with the cellular differentiation of prostate adenocarcinoma, suggesting that loss of RGN may be associated with tumor onset and progression. However, the RGN actions over the control of prostate cell growth have not been investigated.
publishDate 2014
dc.date.none.fl_str_mv 2014-09
2014-09-01T00:00:00Z
2019-12-02T16:59:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/7649
url http://hdl.handle.net/10400.6/7649
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1002/pros.22835
dc.rights.driver.fl_str_mv metadata only access
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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