New Insulins: Opportunities in the Treatment of Type 1 Diabetes

Detalhes bibliográficos
Autor(a) principal: Cabral, Ana Cristina Gaspar
Data de Publicação: 2021
Outros Autores: Semedo, Maria, Lavrador, Mariana Aveiro, Lavrador, Marta, Castel-Branco, Margarida, Figueiredo, Isabel Vitória
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25756/rpf.v13i1.265
Resumo: Type 1 diabetes (T1D) is one of the focuses of scientific research worldwide. Particularities such as its incidence in the younger population, its multifactorial character and the possibility of giving these patients a quality of life and an average life expectancy equal to that of a healthy individual have led to a great investment in research in this area. Since the therapeutic approach of this disease is based on the use of insulin, the progress in the development of new molecules is remarkable. Currently available are new insulins of ultra-fast and ultra-prolonged action, which have revolutionized the treatment of T1D, namely by allowing the mimicking of physiological insulin secretion and thus increasing the effectiveness and safety of therapy. These new insulins have administration and action profiles more adapted and flexible to the diabetic’s day-to-day life, which allows for the optimization of the therapeutic outcome.
id RCAP_baa0aceb304bad1c8101416d24fd8aee
oai_identifier_str oai:ojs.farmacoterapia.pt:article/316
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling New Insulins: Opportunities in the Treatment of Type 1 DiabetesAs Novas Insulinas: Oportunidades no Tratamento da Diabetes Tipo 1Type 1 diabetes (T1D) is one of the focuses of scientific research worldwide. Particularities such as its incidence in the younger population, its multifactorial character and the possibility of giving these patients a quality of life and an average life expectancy equal to that of a healthy individual have led to a great investment in research in this area. Since the therapeutic approach of this disease is based on the use of insulin, the progress in the development of new molecules is remarkable. Currently available are new insulins of ultra-fast and ultra-prolonged action, which have revolutionized the treatment of T1D, namely by allowing the mimicking of physiological insulin secretion and thus increasing the effectiveness and safety of therapy. These new insulins have administration and action profiles more adapted and flexible to the diabetic’s day-to-day life, which allows for the optimization of the therapeutic outcome.A diabetes tipo 1 (DT1) é um dos focos da investigação científica mundial. Particularidades como a sua incidência na população mais jovem, o seu carácter multifatorial e a possibilidade de dar a estes doentes uma qualidade de vida e uma esperança média de vida igual a um indivíduo saudável fazem com que exista um grande investimento na investigação nesta área. Sendo a abordagem terapêutica desta doença baseada na utilização de insulina, são notáveis os progressos no desenvolvimento de novas moléculas. Atualmente, encontram-se disponíveis novas insulinas de ação ultrarrápida e ultra prolongada, que vieram revolucionar o tratamento da DT1, nomeadamente por permitirem mimetizar a secreção fisiológica de insulina e, deste modo, aumentar a efetividade e segurança da terapêutica. Estas novas insulinas apresentam perfis de administração e de ação mais adaptados e flexíveis ao dia-a-dia do diabético, o que permite otimizar o resultado da terapêutica.Formifarma2021-07-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.25756/rpf.v13i1.265https://doi.org/10.25756/rpf.v13i1.265Revista Portuguesa de Farmacoterapia / Portuguese Journal of Pharmacotherapy; Vol 13 No 1 (2021): Janeiro/Fevereiro/Março; 8-18Revista Portuguesa de Farmacoterapia; v. 13 n. 1 (2021): Janeiro/Fevereiro/Março; 8-182183-73411647-354Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://revista.farmacoterapia.pt/index.php/rpf/article/view/316http://revista.farmacoterapia.pt/index.php/rpf/article/view/316/288Direitos de Autor (c) 2021 Revista Portuguesa de Farmacoterapiahttp://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessCabral, Ana Cristina GasparSemedo, MariaLavrador, Mariana AveiroLavrador, MartaCastel-Branco, MargaridaFigueiredo, Isabel Vitória2023-09-01T04:35:08Zoai:ojs.farmacoterapia.pt:article/316Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:11:42.373433Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv New Insulins: Opportunities in the Treatment of Type 1 Diabetes
As Novas Insulinas: Oportunidades no Tratamento da Diabetes Tipo 1
title New Insulins: Opportunities in the Treatment of Type 1 Diabetes
spellingShingle New Insulins: Opportunities in the Treatment of Type 1 Diabetes
Cabral, Ana Cristina Gaspar
title_short New Insulins: Opportunities in the Treatment of Type 1 Diabetes
title_full New Insulins: Opportunities in the Treatment of Type 1 Diabetes
title_fullStr New Insulins: Opportunities in the Treatment of Type 1 Diabetes
title_full_unstemmed New Insulins: Opportunities in the Treatment of Type 1 Diabetes
title_sort New Insulins: Opportunities in the Treatment of Type 1 Diabetes
author Cabral, Ana Cristina Gaspar
author_facet Cabral, Ana Cristina Gaspar
Semedo, Maria
Lavrador, Mariana Aveiro
Lavrador, Marta
Castel-Branco, Margarida
Figueiredo, Isabel Vitória
author_role author
author2 Semedo, Maria
Lavrador, Mariana Aveiro
Lavrador, Marta
Castel-Branco, Margarida
Figueiredo, Isabel Vitória
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cabral, Ana Cristina Gaspar
Semedo, Maria
Lavrador, Mariana Aveiro
Lavrador, Marta
Castel-Branco, Margarida
Figueiredo, Isabel Vitória
description Type 1 diabetes (T1D) is one of the focuses of scientific research worldwide. Particularities such as its incidence in the younger population, its multifactorial character and the possibility of giving these patients a quality of life and an average life expectancy equal to that of a healthy individual have led to a great investment in research in this area. Since the therapeutic approach of this disease is based on the use of insulin, the progress in the development of new molecules is remarkable. Currently available are new insulins of ultra-fast and ultra-prolonged action, which have revolutionized the treatment of T1D, namely by allowing the mimicking of physiological insulin secretion and thus increasing the effectiveness and safety of therapy. These new insulins have administration and action profiles more adapted and flexible to the diabetic’s day-to-day life, which allows for the optimization of the therapeutic outcome.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25756/rpf.v13i1.265
https://doi.org/10.25756/rpf.v13i1.265
url https://doi.org/10.25756/rpf.v13i1.265
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://revista.farmacoterapia.pt/index.php/rpf/article/view/316
http://revista.farmacoterapia.pt/index.php/rpf/article/view/316/288
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2021 Revista Portuguesa de Farmacoterapia
http://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2021 Revista Portuguesa de Farmacoterapia
http://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Formifarma
publisher.none.fl_str_mv Formifarma
dc.source.none.fl_str_mv Revista Portuguesa de Farmacoterapia / Portuguese Journal of Pharmacotherapy; Vol 13 No 1 (2021): Janeiro/Fevereiro/Março; 8-18
Revista Portuguesa de Farmacoterapia; v. 13 n. 1 (2021): Janeiro/Fevereiro/Março; 8-18
2183-7341
1647-354X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799129987109879808