Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/3019 |
Resumo: | BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional CardiologyHSM CARCoronary Thrombosis/diagnosisCoronary Thrombosis/mortalityPortugalCoronary Thrombosis/surgeryHospital MortalityPercutaneous Coronary Intervention/adverse effectsPercutaneous Coronary Intervention/mortalityProtective FactorsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsST Elevation Myocardial Infarction/diagnosisST Elevation Myocardial Infarction/mortalityST Elevation Myocardial Infarction/surgeryThrombectomy/adverse effectsThrombectomy/mortalityTime FactorsTreatment OutcomeBACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.BioMed CentralRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEPereira, HCaldeira, DCampante Teles, RCosta, MCanas da Silva, Pda Gama Ribeiro, VBrandão, VMartins, DMatias, FPereira-Machado, FBaptista, JFarto e Abreu, PSantos, RDrummond, ACyrne de Carvalho, HCalisto, JSilva, JCPipa, JLMarques, JSousa, PFernandes, RCruz Ferreira, RRamos, SInfante Oliveira, Ede Sousa Almeida, M2018-08-07T10:19:33Z2018-04-242018-04-24T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3019engBMC Cardiovasc Disord. 2018 Apr 24;18(1):69.10.1186/s12872-018-0794-4info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:40:51ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
title |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
spellingShingle |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology Pereira, H HSM CAR Coronary Thrombosis/diagnosis Coronary Thrombosis/mortality Portugal Coronary Thrombosis/surgery Hospital Mortality Percutaneous Coronary Intervention/adverse effects Percutaneous Coronary Intervention/mortality Protective Factors Registries Retrospective Studies Risk Assessment Risk Factors ST Elevation Myocardial Infarction/diagnosis ST Elevation Myocardial Infarction/mortality ST Elevation Myocardial Infarction/surgery Thrombectomy/adverse effects Thrombectomy/mortality Time Factors Treatment Outcome |
title_short |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
title_full |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
title_fullStr |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
title_full_unstemmed |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
title_sort |
Thrombus Aspiration in Patients with ST-Elevation Myocardial Infarction: Results of a National Registry of Interventional Cardiology |
author |
Pereira, H |
author_facet |
Pereira, H Caldeira, D Campante Teles, R Costa, M Canas da Silva, P da Gama Ribeiro, V Brandão, V Martins, D Matias, F Pereira-Machado, F Baptista, J Farto e Abreu, P Santos, R Drummond, A Cyrne de Carvalho, H Calisto, J Silva, JC Pipa, JL Marques, J Sousa, P Fernandes, R Cruz Ferreira, R Ramos, S Infante Oliveira, E de Sousa Almeida, M |
author_role |
author |
author2 |
Caldeira, D Campante Teles, R Costa, M Canas da Silva, P da Gama Ribeiro, V Brandão, V Martins, D Matias, F Pereira-Machado, F Baptista, J Farto e Abreu, P Santos, R Drummond, A Cyrne de Carvalho, H Calisto, J Silva, JC Pipa, JL Marques, J Sousa, P Fernandes, R Cruz Ferreira, R Ramos, S Infante Oliveira, E de Sousa Almeida, M |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Pereira, H Caldeira, D Campante Teles, R Costa, M Canas da Silva, P da Gama Ribeiro, V Brandão, V Martins, D Matias, F Pereira-Machado, F Baptista, J Farto e Abreu, P Santos, R Drummond, A Cyrne de Carvalho, H Calisto, J Silva, JC Pipa, JL Marques, J Sousa, P Fernandes, R Cruz Ferreira, R Ramos, S Infante Oliveira, E de Sousa Almeida, M |
dc.subject.por.fl_str_mv |
HSM CAR Coronary Thrombosis/diagnosis Coronary Thrombosis/mortality Portugal Coronary Thrombosis/surgery Hospital Mortality Percutaneous Coronary Intervention/adverse effects Percutaneous Coronary Intervention/mortality Protective Factors Registries Retrospective Studies Risk Assessment Risk Factors ST Elevation Myocardial Infarction/diagnosis ST Elevation Myocardial Infarction/mortality ST Elevation Myocardial Infarction/surgery Thrombectomy/adverse effects Thrombectomy/mortality Time Factors Treatment Outcome |
topic |
HSM CAR Coronary Thrombosis/diagnosis Coronary Thrombosis/mortality Portugal Coronary Thrombosis/surgery Hospital Mortality Percutaneous Coronary Intervention/adverse effects Percutaneous Coronary Intervention/mortality Protective Factors Registries Retrospective Studies Risk Assessment Risk Factors ST Elevation Myocardial Infarction/diagnosis ST Elevation Myocardial Infarction/mortality ST Elevation Myocardial Infarction/surgery Thrombectomy/adverse effects Thrombectomy/mortality Time Factors Treatment Outcome |
description |
BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-08-07T10:19:33Z 2018-04-24 2018-04-24T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/3019 |
url |
http://hdl.handle.net/10400.17/3019 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMC Cardiovasc Disord. 2018 Apr 24;18(1):69. 10.1186/s12872-018-0794-4 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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