The first assessment of hepatitis E virus seroprevalence in northern Portugal.
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366 |
Resumo: | Hepatitis E is an enterically transmitted acute viral hepatitis, etiologically associated with a recently characterized virus, the hepatitis E virus (HEV). Outbreaks mainly occur in developing countries and as sporadic cases in endemic regions. The authors present the first serological assessment in northern Portugal to assess the presence of anti HEV IgG, using the Elisa test, the EIA and HEV Abbott, in samples from 50 blood donors and 103 chronic liver disease patients. In 2 blood donors (4%) and in 7 (6.8%) liver patients, the HEV antibody was detected with optic densities/cut off always below 2.5. Only one patient had a sojourn in an endemic region; the presence of anti-HEV was not significantly associated with other hepatotropic viruses. With this test the authors conclude that 4% of our blood donors are seropositive for anti-HEV antibody and that this percentage is not significantly higher in chronic liver disease patients (6.8%). They also think that a new generation of immunological assays, designed for serological diagnosis of HEV infection, will provide a further understanding of hepatitis E epidemiology. |
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The first assessment of hepatitis E virus seroprevalence in northern Portugal.Primeira avaliação da seroprevalência do vírus da hepatite E no norte de Portugal.Hepatitis E is an enterically transmitted acute viral hepatitis, etiologically associated with a recently characterized virus, the hepatitis E virus (HEV). Outbreaks mainly occur in developing countries and as sporadic cases in endemic regions. The authors present the first serological assessment in northern Portugal to assess the presence of anti HEV IgG, using the Elisa test, the EIA and HEV Abbott, in samples from 50 blood donors and 103 chronic liver disease patients. In 2 blood donors (4%) and in 7 (6.8%) liver patients, the HEV antibody was detected with optic densities/cut off always below 2.5. Only one patient had a sojourn in an endemic region; the presence of anti-HEV was not significantly associated with other hepatotropic viruses. With this test the authors conclude that 4% of our blood donors are seropositive for anti-HEV antibody and that this percentage is not significantly higher in chronic liver disease patients (6.8%). They also think that a new generation of immunological assays, designed for serological diagnosis of HEV infection, will provide a further understanding of hepatitis E epidemiology.Hepatitis E is an enterically transmitted acute viral hepatitis, etiologically associated with a recently characterized virus, the hepatitis E virus (HEV). Outbreaks mainly occur in developing countries and as sporadic cases in endemic regions. The authors present the first serological assessment in northern Portugal to assess the presence of anti HEV IgG, using the Elisa test, the EIA and HEV Abbott, in samples from 50 blood donors and 103 chronic liver disease patients. In 2 blood donors (4%) and in 7 (6.8%) liver patients, the HEV antibody was detected with optic densities/cut off always below 2.5. Only one patient had a sojourn in an endemic region; the presence of anti-HEV was not significantly associated with other hepatotropic viruses. With this test the authors conclude that 4% of our blood donors are seropositive for anti-HEV antibody and that this percentage is not significantly higher in chronic liver disease patients (6.8%). They also think that a new generation of immunological assays, designed for serological diagnosis of HEV infection, will provide a further understanding of hepatitis E epidemiology.Ordem dos Médicos1998-12-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366oai:ojs.www.actamedicaportuguesa.com:article/2366Acta Médica Portuguesa; Vol. 11 No. 12 (1998): Dezembro; 1065-8Acta Médica Portuguesa; Vol. 11 N.º 12 (1998): Dezembro; 1065-81646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366/1784Macedo, GPinto, TSarmento, J AVale, A MRibeiro, Tinfo:eu-repo/semantics/openAccess2022-12-20T11:00:23Zoai:ojs.www.actamedicaportuguesa.com:article/2366Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:41.992186Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. Primeira avaliação da seroprevalência do vírus da hepatite E no norte de Portugal. |
title |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
spellingShingle |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. Macedo, G |
title_short |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
title_full |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
title_fullStr |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
title_full_unstemmed |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
title_sort |
The first assessment of hepatitis E virus seroprevalence in northern Portugal. |
author |
Macedo, G |
author_facet |
Macedo, G Pinto, T Sarmento, J A Vale, A M Ribeiro, T |
author_role |
author |
author2 |
Pinto, T Sarmento, J A Vale, A M Ribeiro, T |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Macedo, G Pinto, T Sarmento, J A Vale, A M Ribeiro, T |
description |
Hepatitis E is an enterically transmitted acute viral hepatitis, etiologically associated with a recently characterized virus, the hepatitis E virus (HEV). Outbreaks mainly occur in developing countries and as sporadic cases in endemic regions. The authors present the first serological assessment in northern Portugal to assess the presence of anti HEV IgG, using the Elisa test, the EIA and HEV Abbott, in samples from 50 blood donors and 103 chronic liver disease patients. In 2 blood donors (4%) and in 7 (6.8%) liver patients, the HEV antibody was detected with optic densities/cut off always below 2.5. Only one patient had a sojourn in an endemic region; the presence of anti-HEV was not significantly associated with other hepatotropic viruses. With this test the authors conclude that 4% of our blood donors are seropositive for anti-HEV antibody and that this percentage is not significantly higher in chronic liver disease patients (6.8%). They also think that a new generation of immunological assays, designed for serological diagnosis of HEV infection, will provide a further understanding of hepatitis E epidemiology. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-12-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366 oai:ojs.www.actamedicaportuguesa.com:article/2366 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/2366 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2366/1784 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 11 No. 12 (1998): Dezembro; 1065-8 Acta Médica Portuguesa; Vol. 11 N.º 12 (1998): Dezembro; 1065-8 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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