Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.14/42838 |
Resumo: | To assess the clinical efficacy of a novel organic olive oil-based denture adhesive and its effect on Candida Albicans growth in maxillary edentulous individuals wearing complete dentures. Individuals were selected from two Dental Schools in Portugal and Spain. Twenty-eight complete dentures were relined, following a standardized protocol. The novel product (Test) was compared with a commercialized adhesive (Control) and Vaseline (Placebo) randomly assigned in a crossstudy design. The retention resistance was measured with a Gnathometer and a dynamometer, the patient related outcome evaluations with a 5-points questionnaire and the Candida albicans growth in a Sabouraud dextrose agar (SDA) medium in order to evaluate differences between the placebo and experimental product. Twenty-three participants were included. Dynamometer evaluation showed significant differences between not using a denture adhesive and using either (experimental, p = .03; control, p = .04), no significant differences between the two adhesives (p > .05). In the subjective analysis, the experimental adhesive showed a significantly longer effectiveness (p = .001); the control reported better results at taste (p = .03) in chewing (p = .001). The test adhesive showed better (p < .001) Candida albicans growth inhibition. The experimental adhesive showed longer effectiveness than the control and placebo with a better inhibition capacity for the growth of Candida albicans, patients reported better abilities for speech, chewing, taste and retirement in the control adhesive. |
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Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trialProsthodonticsEdentulismElderlyComplete DentureCandida AlbicansAntimicrobial activityTo assess the clinical efficacy of a novel organic olive oil-based denture adhesive and its effect on Candida Albicans growth in maxillary edentulous individuals wearing complete dentures. Individuals were selected from two Dental Schools in Portugal and Spain. Twenty-eight complete dentures were relined, following a standardized protocol. The novel product (Test) was compared with a commercialized adhesive (Control) and Vaseline (Placebo) randomly assigned in a crossstudy design. The retention resistance was measured with a Gnathometer and a dynamometer, the patient related outcome evaluations with a 5-points questionnaire and the Candida albicans growth in a Sabouraud dextrose agar (SDA) medium in order to evaluate differences between the placebo and experimental product. Twenty-three participants were included. Dynamometer evaluation showed significant differences between not using a denture adhesive and using either (experimental, p = .03; control, p = .04), no significant differences between the two adhesives (p > .05). In the subjective analysis, the experimental adhesive showed a significantly longer effectiveness (p = .001); the control reported better results at taste (p = .03) in chewing (p = .001). The test adhesive showed better (p < .001) Candida albicans growth inhibition. The experimental adhesive showed longer effectiveness than the control and placebo with a better inhibition capacity for the growth of Candida albicans, patients reported better abilities for speech, chewing, taste and retirement in the control adhesive.Preprints.orgVeritati - Repositório Institucional da Universidade Católica PortuguesaAzevedo, LuísCorreia, AndréAlmeida, Carlos F.Molinero-Mourelle, PedroCorreia, MariaHisghsmith, Jaime Del Río2023-10-11T13:06:20Z2021-02-082021-02-08T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/42838eng10.20944/preprints202102.0222.v1info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-17T01:36:13Zoai:repositorio.ucp.pt:10400.14/42838Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:35:48.992630Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
title |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
spellingShingle |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial Azevedo, Luís Prosthodontics Edentulism Elderly Complete Denture Candida Albicans Antimicrobial activity |
title_short |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
title_full |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
title_fullStr |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
title_full_unstemmed |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
title_sort |
Biocompatibility and effectiveness of a novel organic olive oil-based denture adhesive: a multicenter randomized and placebo-controlled clinical trial |
author |
Azevedo, Luís |
author_facet |
Azevedo, Luís Correia, André Almeida, Carlos F. Molinero-Mourelle, Pedro Correia, Maria Hisghsmith, Jaime Del Río |
author_role |
author |
author2 |
Correia, André Almeida, Carlos F. Molinero-Mourelle, Pedro Correia, Maria Hisghsmith, Jaime Del Río |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Veritati - Repositório Institucional da Universidade Católica Portuguesa |
dc.contributor.author.fl_str_mv |
Azevedo, Luís Correia, André Almeida, Carlos F. Molinero-Mourelle, Pedro Correia, Maria Hisghsmith, Jaime Del Río |
dc.subject.por.fl_str_mv |
Prosthodontics Edentulism Elderly Complete Denture Candida Albicans Antimicrobial activity |
topic |
Prosthodontics Edentulism Elderly Complete Denture Candida Albicans Antimicrobial activity |
description |
To assess the clinical efficacy of a novel organic olive oil-based denture adhesive and its effect on Candida Albicans growth in maxillary edentulous individuals wearing complete dentures. Individuals were selected from two Dental Schools in Portugal and Spain. Twenty-eight complete dentures were relined, following a standardized protocol. The novel product (Test) was compared with a commercialized adhesive (Control) and Vaseline (Placebo) randomly assigned in a crossstudy design. The retention resistance was measured with a Gnathometer and a dynamometer, the patient related outcome evaluations with a 5-points questionnaire and the Candida albicans growth in a Sabouraud dextrose agar (SDA) medium in order to evaluate differences between the placebo and experimental product. Twenty-three participants were included. Dynamometer evaluation showed significant differences between not using a denture adhesive and using either (experimental, p = .03; control, p = .04), no significant differences between the two adhesives (p > .05). In the subjective analysis, the experimental adhesive showed a significantly longer effectiveness (p = .001); the control reported better results at taste (p = .03) in chewing (p = .001). The test adhesive showed better (p < .001) Candida albicans growth inhibition. The experimental adhesive showed longer effectiveness than the control and placebo with a better inhibition capacity for the growth of Candida albicans, patients reported better abilities for speech, chewing, taste and retirement in the control adhesive. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-08 2021-02-08T00:00:00Z 2023-10-11T13:06:20Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.14/42838 |
url |
http://hdl.handle.net/10400.14/42838 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.20944/preprints202102.0222.v1 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Preprints.org |
publisher.none.fl_str_mv |
Preprints.org |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133621749022720 |