Primary solitary amyloidoma of the lumbar spine

• Autor(a) principal: Murinello, António
• Data de Publicação: 2008
• Outros Autores: Figueiredo Coelho, J., Mendonça, Paula, Milheiro, Adelaide, Lázaro, António, Arias, Jesus, Teiga, Carlos, Simões, José, Carvalho, Fernanda, Peres, Helena
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1450
• topic: amiloidoma primário; coluna lombar; amiloidose; primary amyloidoma; lumbar spine; amyloidosis

Primary solitary amyloidoma of the spine is an extremely rare form of localized deposits of amyloid on bone tissue and has a predilection for the thoracic region. It arises within the bone marrow of the vertebral body, causing pain and neurologic symptoms due to bone destruction with fracture and collapse, visible on imagiologic studies as osteolytic lesions usually associated with adjacent soft tissue masses. The duration of symptomatology can be of several years before diagnosis, although clinical deterioration may be rapid and severe, with acute neurologic compression, radiculopathy, myelopathy and paraplegia, leading to the necessity of emergency surgery. The prognosis after total excision and spinal stabilization is generally excellent, as patients with solitary amyloidoma have no known risk of development of multiple myeloma or systemic amyloidosis. The authors report the case of a patient with solitary amyloidoma of the lumbar spine who unfortunately had a dismal outcome, due to acute nosocomial pneumonia and sepsis by Acinetobacter baumanii and extended-spectrum β-lactamase Escherichia coli occurring after open spinal biopsy.