Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review

Detalhes bibliográficos
Autor(a) principal: Alpuim Costa, D
Data de Publicação: 2021
Outros Autores: Amaro, CE, Nunes, A, Cardoso, JS, Daniel, PM, Rosa, I, Branco, JV
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/37337
Resumo: Radiotherapy (RT) is the backbone of multimodality treatment of more than half of cancer cases. Despite new modern RT techniques, late complications may occur such as radiation proctitis (RP). The natural history of RP is unpredictable. Minor symptoms may resolve spontaneously or require conservative treatment. On the other hand, for similar and uncomplicated clinical contexts, symptoms may persist and can even be refractory to the progressive increase in treatment measures. Over the last decades, an enormous therapeutic armamentarium has been considered in RP, including hyperbaric oxygen therapy (HBOT). Currently, the evidence regarding the impact of HBOT on RP and its benefits is conflicting. Additional prospective and randomised studies are necessary to validate HBOT's effectiveness in the 'real world' clinical practice. This article reviewed the relevant literature on pathophysiology, clinical presentation, different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT.
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spelling Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature reviewOxigenoterapia HiperbáricaProctiteLesões por RadiaçãoHyperbaric OxygenationProctitisRadiation InjuriesRadiotherapy (RT) is the backbone of multimodality treatment of more than half of cancer cases. Despite new modern RT techniques, late complications may occur such as radiation proctitis (RP). The natural history of RP is unpredictable. Minor symptoms may resolve spontaneously or require conservative treatment. On the other hand, for similar and uncomplicated clinical contexts, symptoms may persist and can even be refractory to the progressive increase in treatment measures. Over the last decades, an enormous therapeutic armamentarium has been considered in RP, including hyperbaric oxygen therapy (HBOT). Currently, the evidence regarding the impact of HBOT on RP and its benefits is conflicting. Additional prospective and randomised studies are necessary to validate HBOT's effectiveness in the 'real world' clinical practice. This article reviewed the relevant literature on pathophysiology, clinical presentation, different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT.Repositório ComumAlpuim Costa, DAmaro, CENunes, ACardoso, JSDaniel, PMRosa, IBranco, JV2021-08-17T21:05:20Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/37337engWorld J Gastroenterol . 2021 Jul 21;27(27):4413-4428.10.3748/wjg.v27.i27.4413info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:25:26Zoai:comum.rcaap.pt:10400.26/37337Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:22:56.857487Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
title Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
spellingShingle Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
Alpuim Costa, D
Oxigenoterapia Hiperbárica
Proctite
Lesões por Radiação
Hyperbaric Oxygenation
Proctitis
Radiation Injuries
title_short Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
title_full Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
title_fullStr Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
title_full_unstemmed Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
title_sort Hyperbaric oxygen therapy as a complementary treatment for radiation proctitis: Useless or useful? – A literature review
author Alpuim Costa, D
author_facet Alpuim Costa, D
Amaro, CE
Nunes, A
Cardoso, JS
Daniel, PM
Rosa, I
Branco, JV
author_role author
author2 Amaro, CE
Nunes, A
Cardoso, JS
Daniel, PM
Rosa, I
Branco, JV
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Alpuim Costa, D
Amaro, CE
Nunes, A
Cardoso, JS
Daniel, PM
Rosa, I
Branco, JV
dc.subject.por.fl_str_mv Oxigenoterapia Hiperbárica
Proctite
Lesões por Radiação
Hyperbaric Oxygenation
Proctitis
Radiation Injuries
topic Oxigenoterapia Hiperbárica
Proctite
Lesões por Radiação
Hyperbaric Oxygenation
Proctitis
Radiation Injuries
description Radiotherapy (RT) is the backbone of multimodality treatment of more than half of cancer cases. Despite new modern RT techniques, late complications may occur such as radiation proctitis (RP). The natural history of RP is unpredictable. Minor symptoms may resolve spontaneously or require conservative treatment. On the other hand, for similar and uncomplicated clinical contexts, symptoms may persist and can even be refractory to the progressive increase in treatment measures. Over the last decades, an enormous therapeutic armamentarium has been considered in RP, including hyperbaric oxygen therapy (HBOT). Currently, the evidence regarding the impact of HBOT on RP and its benefits is conflicting. Additional prospective and randomised studies are necessary to validate HBOT's effectiveness in the 'real world' clinical practice. This article reviewed the relevant literature on pathophysiology, clinical presentation, different classifications and discuss RP management including a proposal for a therapeutic algorithm with a focus on HBOT.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-17T21:05:20Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/37337
url http://hdl.handle.net/10400.26/37337
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv World J Gastroenterol . 2021 Jul 21;27(27):4413-4428.
10.3748/wjg.v27.i27.4413
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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