Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review

Detalhes bibliográficos
Autor(a) principal: Silva, S
Data de Publicação: 2019
Outros Autores: Almeida, A, Vale, N
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/136270
Resumo: Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.
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spelling Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A reviewCell-penetrating peptidesDelivery systemsMembrane translocationNanoparticlesTherapeutic moleculeCell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.MDPI20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/136270eng2218-273X10.3390/biom9010022Silva, SAlmeida, AVale, Ninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T12:45:44Zoai:repositorio-aberto.up.pt:10216/136270Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:26:15.241630Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
title Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
spellingShingle Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
Silva, S
Cell-penetrating peptides
Delivery systems
Membrane translocation
Nanoparticles
Therapeutic molecule
title_short Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
title_full Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
title_fullStr Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
title_full_unstemmed Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
title_sort Combination of cell-penetrating peptides with nanoparticles for therapeutic application: A review
author Silva, S
author_facet Silva, S
Almeida, A
Vale, N
author_role author
author2 Almeida, A
Vale, N
author2_role author
author
dc.contributor.author.fl_str_mv Silva, S
Almeida, A
Vale, N
dc.subject.por.fl_str_mv Cell-penetrating peptides
Delivery systems
Membrane translocation
Nanoparticles
Therapeutic molecule
topic Cell-penetrating peptides
Delivery systems
Membrane translocation
Nanoparticles
Therapeutic molecule
description Cell-penetrating peptides (CPPs), also known as protein translocation domains, membrane translocating sequences or Trojan peptides, are small molecules of 6 to 30 amino acid residues capable of penetrating biological barriers and cellular membranes. Furthermore, CPP have become an alternative strategy to overcome some of the current drug limitations and combat resistant strains since CPPs are capable of delivering different therapeutic molecules against a wide range of diseases. In this review, we address the recent conjugation of CPPs with nanoparticles, which constitutes a new class of delivery vectors with high pharmaceutical potential in a variety of diseases.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/136270
url https://hdl.handle.net/10216/136270
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2218-273X
10.3390/biom9010022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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